Effects of dietary methionine supplementation on growth performance, intestinal morphology, antioxidant capacity and immune function in intra‐uterine growth‐retarded suckling piglets

2019 ◽  
Vol 103 (3) ◽  
pp. 868-881 ◽  
Author(s):  
Hao Zhang ◽  
Yue Li ◽  
Yueping Chen ◽  
Zhixiong Ying ◽  
Weipeng Su ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Immune Function ◽  
Growth Performance ◽  
Intestinal Morphology ◽  
Uterine Growth ◽  
Suckling Piglets ◽  
Methionine Supplementation

scholarly journals Effects of high nutrient intake on the growth performance, intestinal morphology and immune function of neonatal intra-uterine growth-retarded pigs

2013 ◽  
Vol 110 (10) ◽  
pp. 1819-1827 ◽  
Author(s):  
Fei Han ◽  
Liang Hu ◽  
Yue Xuan ◽  
Xuemei Ding ◽  
Yuheng Luo ◽  
...  
Keyword(s):  
Immune Function ◽  
Growth Performance ◽  
Nutrient Intake ◽  
Intestinal Morphology ◽  
Nutrient Level ◽  
Suckling Period ◽  
Gene Expressions ◽  
Serum Cytokines ◽  
Tnf Α ◽  
Uterine Growth

Intra-uterine growth-retarded (IUGR) neonates have shown an impairment of postnatal intestinal development and function. We hypothesised that the immune function of IUGR neonates might be affected by increased nutrient intake (NI) during the suckling period. Therefore, we investigated the effects of high NI (HNI) on the growth performance, intestinal morphology and immunological response of IUGR and normal-birth weight (NBW) piglets. A total of twelve pairs of IUGR and NBW piglets (7 d old) were randomly assigned to two different nutrient-level formula milk groups. After 21 d of rearing, growth performance, the composition of peripheral leucocytes, serum cytokines and intestinal innate immune-related genes involved in the Toll-like receptor (TLR)-4–myeloid differentiation factor 88–NF-κB pathway were determined. The results indicated that IUGR decreased the average daily DM intake (ADMI) and the average daily growth (ADG). However, the ADMI and ADG were increased by HNI, irrespective of body weight. Likewise, serum cytokines (TNF-α and IL-1β) and ileal gene expressions (TLR-4, TLR-9, TRAF-6 and IL-1β) were lower in IUGR piglets, whereas HNI significantly increased blood lymphocyte percentage and serum IL-10 concentrations, but decreased neutrophil percentage, serum IL-1β concentrations and ileal gene expressions (NF-κB and IL-1β). Furthermore, IUGR piglets with HNI exhibited lower serum concentrations of TNF-α and IL-1β than NBW piglets, and these alterations in the immune traits of IUGR piglets receiving HNI were accompanied by decreasing ileal gene expressions of TLR-4, TLR-9, NF-κB and IL-1β that are related to innate immunity. In conclusion, the present findings suggest that increased NI during the suckling period impaired the immune function of neonatal piglets with IUGR.

scholarly journals Effects of a yeast-derived product on growth performance, antioxidant capacity and immune function of broilers

2021 ◽  
pp. 101343
Author(s):  
Ting Wang ◽  
Kang Cheng ◽  
CaiYun Yu ◽  
QiMing Li ◽  
YiChun Tong ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Immune Function ◽  
Growth Performance

Effects of Clostridium butyricum and Enterococcus faecalis on growth performance, immune function, intestinal morphology, volatile fatty acids, and intestinal flora in a piglet model

2019 ◽  
Vol 10 (12) ◽  
pp. 7844-7854 ◽  
Author(s):  
Kangli Wang ◽  
Guangtian Cao ◽  
Haoran Zhang ◽  
Qing Li ◽  
Caimei Yang
Keyword(s):  
Fatty Acids ◽  
Immune Function ◽  
Growth Performance ◽  
Enterococcus Faecalis ◽  
Volatile Fatty Acids ◽  
Intestinal Flora ◽  
Clostridium Butyricum ◽  
Intestinal Morphology

We investigated the effects of Clostridium butyricum and Enterococcus faecalis (probiotics) in a piglet model.

scholarly journals PSVI-40 Effects of dietary glucan on intestinal morphology, immunity response, barrier function and antioxidant capacity in weaning pigs

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 212-213
Author(s):  
xia xiong ◽  
Lvliang Wu ◽  
Yirui Shao ◽  
Jian zou ◽  
Yulong Yin
Keyword(s):  
Antioxidant Capacity ◽  
Growth Performance ◽  
Mrna Expression ◽  
Dietary Supplementation ◽  
Basal Diet ◽  
Intestinal Morphology ◽  
Control Group ◽  
Gut Health ◽  
Weaned Piglets ◽  
Weaning Piglets

Abstract Glucan has been studied as a potential alternative to antibiotics for animals in recent years. The aim of this study was to evaluate the effect of dietary glucan on growth performance and gut health of weaning piglets, which is a water-soluble extracellular ꞵ-glucan produced by Agrobacterium sp. ZX09. A total of 108 weaned piglets (21 d of age; 6.05 ± 0.36 kg) were randomly assigned (6 pens/diet; 18 piglets/pen) to 3 dietary treatments consisting of a basal diet (control group) or the basal diet supplemented with 20 ppm olaquindox or 200 ppm glucan for 14 days, respectively. The results showed that piglets fed with glucan had greater (P < 0.05) body weight and average daily gain than piglets in control group. Piglets fed with glucan or antibiotic had greater villus height to crypt depth ratio on duodenum compared with control group (P < 0.05). The mRNA expression of Claudin-1 on duodenum or ileum was higher (P < 0.05) in glucan group than that on the other groups. The mRNA expression of TLR4, MYD88 and NFκB on jejunum were lower (P < 0.05) in glucan or antibiotic group than those in control group. Dietary supplementation with glucan tended to increase the IL-10 and SIgA concentration on ileum (0.05 < P < 0.1). Dietary supplementation with glucan tended to increase the total antioxidant capacity on jejunum (P = 0.093). In conclusion, 200 ppm glucan or 20 ppm olaquindox can improve the growth performance of weaning piglets. The glucan may can accelerate the growth of weaned piglets by improving gut health. This research will provide guidance for the olaquindox alternative on growing piglets.

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