Effects of lysolecithin and xylanase supplementation on the growth performance, nutrient digestibility and lipogenic gene expression in broilers fed low-energy wheat-based diets

2018 ◽  
Vol 102 (6) ◽  
pp. 1564-1573 ◽  
Author(s):  
Seyyed M. Hosseini ◽  
Rouhollah Nourmohammadi ◽  
Hasan Nazarizadeh ◽  
J. David Latshaw
Keyword(s):  
Gene Expression ◽  
Growth Performance ◽  
Nutrient Digestibility ◽  
Low Energy ◽  
Lipogenic Gene ◽  
Lipogenic Gene Expression

Dietary supplementation with L-arginine and combinations of different oil sources beneficially regulates body fat deposition, lipogenic gene expression, growth performance and carcass yield in broiler chickens

2020 ◽  
Vol 60 (11) ◽  
pp. 1409 ◽  
Author(s):  
J. Khatun ◽  
T. C. Loh ◽  
H. Akit ◽  
H. L. Foo ◽  
R. Mohamad ◽  
...  
Keyword(s):  
Gene Expression ◽  
Fatty Acids ◽  
Fatty Acid ◽  
Growth Performance ◽  
Broiler Chickens ◽  
Abdominal Fat ◽  
Fat Deposition ◽  
Carcass Yield ◽  
Lipogenic Gene ◽  
Lipogenic Gene Expression

Context Broiler meat with excessive of fat and saturated fatty acids content has serious health implication for consumers. The accumulation of abdominal fats in broiler chickens constitutes a loss of dietary energy and also reduces carcass yield. Oil rich in unsaturated fatty acids and l-arginine are effective for reducing fat deposition and improve meat quality. Aims The aim of this study was to examine the effects of supplementation of l-arginine (l-Arg) with four combinations of palm oil (PO) and sunflower oil (SO) on growth performance, carcass yield, fat deposition, lipogenic gene expression and blood lipid profile in broiler chickens. Methods A total of 180 1-day-old chicks (Cobb 500) were randomly assigned to five dietary treatments as: T1, 6% PO (control); T2, 6% PO + 0.25% l-Arg; T3, 4% PO + 2% SO + 0.25% l-Arg; T4, 2% PO + 4% SO + 0.25% l-Arg; and T5, 6% SO + 0.25% l-Arg. Key results Birds fed l-Arg and combinations of PO and SO had higher weight gain at starter and finisher period compared with the control. The carcass yield increased, and relative abdominal fat reduced in broiler fed with combinations of l-Arg and increased level of SO in the diet. The concentration of oleic, palmitoleic and total monounsaturated fatty acids in liver tissue decreased by addition of l-Arg in broiler diet. The palmitic and total saturated fatty acid decreased, and total unsaturated fatty acid and polyunsaturated fatty acids increased in liver tissue when PO replaced progressively by SO supplemented with l-Arg in the diet. The acetyl-CoA carboxylase , stearoyl-CoA desaturase and fatty acid synthetase gene expression tended to decrease by supplementation of l-Arg with an increased level of SO compared with control. Conclusion Supplementation with l-Arg and combination of PO and SO at the ratio of 4:2 could inhibit lipogenesis and subsequent lower abdominal fat deposition and enhance growth performance and carcass yield in broiler chickens. Implications Ratio of PO and SO, 4:2 with l-Arg supplementation in the dietary of broiler chickens can contribute to a better growth performance, lesser fat deposition and greater carcass yield.

The effect of feeding excess arginine on lipogenic gene expression and growth performance in broilers

2014 ◽  
Vol 55 (1) ◽  
pp. 81-88 ◽  
Author(s):  
M. Ebrahimi ◽  
A. Zare Shahneh ◽  
M. Shivazad ◽  
Z. Ansari Pirsaraei ◽  
M. Tebianian ◽  
...  
Keyword(s):  
Gene Expression ◽  
Growth Performance ◽  
Lipogenic Gene ◽  
Lipogenic Gene Expression ◽  
Effect Of Feeding

scholarly journals Effects of Fattening Period on Growth Performance, Carcass Characteristics and Lipogenic Gene Expression in Hanwoo Steers

2009 ◽  
Vol 22 (12) ◽  
pp. 1654-1660 ◽  
Author(s):  
Eung Gi Kwon ◽  
Byung Ki Park ◽  
Hyeong Cheol Kim ◽  
Young Moo Cho ◽  
Tae Il Kim ◽  
...  
Keyword(s):  
Gene Expression ◽  
Growth Performance ◽  
Carcass Characteristics ◽  
Lipogenic Gene ◽  
Lipogenic Gene Expression ◽  
Fattening Period

scholarly journals Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1

2010 ◽  
Vol 432 (2) ◽  
pp. 249-254 ◽  
Author(s):  
Aldo Grefhorst ◽  
Marijke Schreurs ◽  
Maaike H. Oosterveer ◽  
Victor A. Cortés ◽  
Rick Havinga ◽  
...  
Keyword(s):  
Gene Expression ◽  
Binding Protein ◽  
Glycogen Storage Disease Type ◽  
Glycogen Storage ◽  
Hepatic Glycogen ◽  
Lipogenic Gene ◽  
Lipogenic Gene Expression ◽  
Liver X Receptor Α ◽  
Element Binding Protein

GSD-1 (glycogen storage disease type 1) is caused by an inherited defect in glucose-6-phosphatase activity, resulting in a massive accumulation of hepatic glycogen content and an induction of de novo lipogenesis. The chlorogenic acid derivative S4048 is a pharmacological inhibitor of the glucose 6-phosphate transporter, which is part of glucose-6-phosphatase, and allows for mechanistic studies concerning metabolic defects in GSD-1. Treatment of mice with S4048 resulted in an ~60% reduction in blood glucose, increased hepatic glycogen and triacylglycerol (triglyceride) content, and a markedly enhanced hepatic lipogenic gene expression. In mammals, hepatic expression of lipogenic genes is regulated by the co-ordinated action of the transcription factors SREBP (sterol-regulatory-element-binding protein)-1c, LXRα (liver X receptor α) and ChREBP (carbohydrate-response-element-binding protein). Treatment of Lxra−/− mice and Chrebp−/− mice with S4048 demonstrated that ChREBP, but not LXRα, mediates the induction of hepatic lipogenic gene expression in this murine model of GSD-1. Thus ChREBP is an attractive target to alleviate derangements in lipid metabolism observed in patients with GSD-1.

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