The protective effect of γ-aminobutyric acid on the development of immune function in chickens under heat stress

2015 ◽  
Vol 100 (4) ◽  
pp. 768-777 ◽  
Author(s):  
J. Tang ◽  
Z. Chen
2003 ◽  
Vol 69 (7) ◽  
pp. 4123-4128 ◽  
Author(s):  
R. T. Bacon ◽  
J. R. Ransom ◽  
J. N. Sofos ◽  
P. A. Kendall ◽  
K. E. Belk ◽  
...  

ABSTRACT The heat resistance of susceptible and multiantimicrobial-resistant Salmonella strains grown to stationary phase in glucose-free tryptic soy broth supplemented with 0.6% yeast extract (TSBYE−G; nonadapted), in regular (0.25% glucose) TSBYE, or in TSBYE−G with 1.00% added glucose (TSBYE+G; acid adapted) was determined at 55, 57, 59, and 61°C. Cultures were heated in sterile 0.1% buffered peptone water (50 μl) in heat-sealed capillary tubes immersed in a thermostatically controlled circulating-water bath. Decimal reduction times (D values) were calculated from survival curves having r 2 values of >0.90 as a means of comparing thermal tolerance among variables. D 59°C values increased (P < 0.05) from 0.50 to 0.58 to 0.66 min for TSBYE−G, TSBYE, and TSBYE+G cultures, respectively. D 61°C values of antimicrobial-susceptible Salmonella strains increased (P < 0.05) from 0.14 to 0.19 as the glucose concentration increased from 0.00 to 1.00%, respectively, while D 61°C values of multiantimicrobial-resistant Salmonella strains did not differ (P > 0.05) between TSBYE−G and TSBYE+G cultures. When averaged across glucose levels and temperatures, there were no differences (P > 0.05) between the D values of susceptible and multiantimicrobial-resistant inocula. Collectively, D values ranged from 4.23 to 5.39, 1.47 to 1.81, 0.50 to 0.66, and 0.16 to 0.20 min for Salmonella strains inactivated at 55, 57, 59, and 61°C, respectively. zD values were 1.20, 1.48, and 1.49°C for Salmonella strains grown in TSBYE+G, TSBYE, and TSBYE−G, respectively, while the corresponding activation energies of inactivation were 497, 493, and 494 kJ/mol. Study results suggested a cross-protective effect of acid adaptation on thermal inactivation but no association between antimicrobial susceptibility and the ability of salmonellae to survive heat stress.


Aquaculture ◽  
2014 ◽  
Vol 432 ◽  
pp. 26-37 ◽  
Author(s):  
Celia Hooper ◽  
Rob Day ◽  
Ron Slocombe ◽  
Kirsten Benkendorff ◽  
Judith Handlinger ◽  
...  

Author(s):  
Anjali Aggarwal ◽  
Ramesh Upadhyay
Keyword(s):  

2020 ◽  
Vol 65 (No. 3) ◽  
pp. 104-113 ◽  
Author(s):  
Shaojun He ◽  
Qirun Yin ◽  
Yongjie Xiong ◽  
Deyi Liu ◽  
Hong Hu

This study aimed to investigate the effects of dietary fumaric acid (FA) on growth performance, immune responses, immune organ index and antioxidant status in broilers under chronic heat stress (HS). A total of 200 21-day-old Ross 308 chicks were randomly assigned in a 2 × 2 factorial arrangement with two diets (basal diet or 10 g/kg FA diet) and two temperatures (thermoneutral or HS) for 21 days. On day 42, growth performance, immune organ index, immune function and antioxidative ability were determined. HS resulted in a significant reduction in final body weight (FBW), average daily feed intake (ADFI), average daily gain (ADG), antibody titres against sheep red blood cells (SRBC) and Newcastle disease virus, IgM, IgG, relative weights of spleen, thymus and bursa of Fabricius, but a significant increase in the feed conversion ratio (FCR), activities of total superoxide dismutase (T-SOD) and glutathione peroxidase (GPx) in the bursa, contents of malondialdehyde and total carbonyl (TC) in thymus and bursa (P &lt; 0.05). Dietary supplementation of FA increased FBW, ADFI, ADG, antibody titres against SRBC, IgG, relative weights of spleen and bursa, activity of GPx in thymus and bursa, whereas it decreased the FCR and TC of thymus and bursa. These results suggest that dietary 10 g/kg FA had positive effects on growth performance and immune function through improving the antioxidative capacity of immune organs.


2020 ◽  
Vol 269 ◽  
pp. 114635
Author(s):  
Q. Shan ◽  
F.T. Ma ◽  
Y.H. Jin ◽  
D. Gao ◽  
H.Y. Li ◽  
...  

2004 ◽  
Vol 42 (12) ◽  
pp. 2009-2014 ◽  
Author(s):  
Hyun Young Kim ◽  
Takako Yokozawa ◽  
Takako Nakagawa ◽  
Sumiyo Sasaki

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