Recovery of intact IgG in the gastrointestinal tract of the growing rat following ingestion of an ovine serum immunoglobulin

2013 ◽  
Vol 98 (2) ◽  
pp. 209-214 ◽  
Author(s):  
P. Balan ◽  
K.S. Han ◽  
V.S.R. Dukkipati ◽  
P.J. Moughan
Keyword(s):  
Gastrointestinal Tract ◽  
Serum Immunoglobulin ◽  
Growing Rat

Spray-dried porcine plasma and yeast derived protein meal influence the adaption to weaning of primiparous and multiparous sow progeny in different ways

2013 ◽  
Vol 53 (1) ◽  
pp. 75 ◽  
Author(s):  
M. V. Edwards ◽  
R. G. Campbell ◽  
T. Chapman ◽  
H. Brouwers ◽  
S. G. Pierzynowski ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Growth Performance ◽  
Immunoglobulin G ◽  
Average Daily Gain ◽  
Serum Immunoglobulin ◽  
Yeast Protein ◽  
Protein Meal ◽  
Immune Parameters ◽  
Daily Gain ◽  
Spray Dried

Pigs from 154 litters (n = 1132, 19 ± 3 days of age, 4.9 ± 1.1 kg of bodyweight) were used in a 3 × 2 factorial design to evaluate two raw materials with nutraceutical properties being used in feeds, spray-dried porcine plasma (SDPP) and a yeast protein meal, and their effects on growth performance, immune parameters and gastrointestinal adaption of piglets to weaning. Factors included dietary treatments being (1) 5% SDPP (PLA), (2) 3.5% yeast protein meal (NUP) and (3) medicated control (TMC) and parity (primiparous versus multiparous). The treatment groups were imposed from Day 19 through to weaning at Day 27. Selected pigs (n = 720, 28 ± 3 days of age, 7.4 ± 1.0 kg of bodyweight) were weaned and remained on their respective diets from Day 28 to Day 34. From Day 35 to Day 48 all group-housed pigs were offered a commercial weaner 1 diet, and from Day 49 to Day 68 pigs were offered a commercial weaner 2 diet. Growth performance, survival, and serum immunoglobulin G were monitored throughout the nursery phase (Day 28 to Day 68). Adaptation of the gastrointestinal tract in the acute post-weaning phase (Day 28 to Day 34) was assessed in 36 individually housed male weaners, with the effects of feed on structural, digestive, microbial and immune parameters along the gastrointestinal tract determined at Day 34. Pre-weaning feed disappearance was greater (P < 0.01) in multiparous litters independent of diet. In the commercial nursery, total removals (mortality and morbidity) were highest (P < 0.01) in primiparous sow progeny, with pigs offered NUP having greater (P ≤ 0.05) total removals. Pigs offered PLA had superior average daily gain, average daily feed intake and feed conversion ratio from Day 28 to Day 34 (P < 0.05). Pigs offered NUP tended to (P = 0.07) have superior average daily gain from Day 35 to Day 49. Pigs offered NUP had higher (P < 0.05) serum immunoglobulin G concentrations at Day 68 compared with pigs offered TMC, with the effect most pronounced in primiparous sow progeny. Individually housed weaners offered PLA consumed more (P < 0.05) feed on Day 30 to Day 31, had shorter relative intestine length (P < 0.05), greater villous height in the medial jejunum (P < 0.10) and lower immuno-pathology scores along the intestine. Pigs offered PLA also tended (P < 0.10) to have increased pancreatic-specific lipase and amylase activity compared with pigs offered NUP. Pigs offered NUP had a higher ratio of E. coli : coliforms in the colon (P < 0.01) and more counts of β-haemolytic bacteria in the medial jejunum (P < 0.05) and colon (P < 0.10). Diets containing either SDPP or NUP offered pigs benefits beyond nutrition relative to the medicated control diet. The benefits of SDPP were highly effective but transient, while the yeast derived protein had a successive or accumulative effect which was more pronounced in primiparous sow progeny.

scholarly journals Immunomodulatory effects of ovine serum immunoglobulin in the growing rat

animal ◽  
2010 ◽  
Vol 4 (10) ◽  
pp. 1702-1708 ◽  
Author(s):  
P. Balan ◽  
K.S. Han ◽  
K. Rutherfurd-Markwick ◽  
H. Singh ◽  
P.J. Moughan
Keyword(s):  
Serum Immunoglobulin ◽  
Immunomodulatory Effects ◽  
Growing Rat

Habitat Association of Klebsiella Species

1985 ◽  
Vol 6 (2) ◽  
pp. 52-58 ◽  
Author(s):  
Susan T. Bagley
Keyword(s):  
Drinking Water ◽  
Gastrointestinal Tract ◽  
Surface Waters ◽  
Industrial Effluents ◽  
Opportunistic Pathogen ◽  
Habitat Associations ◽  
Habitat Association ◽  
Klebsiella Species ◽  
Almost All ◽  
Polluted Waters

AbstractThe genus Klebsiella is seemingly ubiquitous in terms of its habitat associations. Klebsiella is a common opportunistic pathogen for humans and other animals, as well as being resident or transient flora (particularly in the gastrointestinal tract). Other habitats include sewage, drinking water, soils, surface waters, industrial effluents, and vegetation. Until recently, almost all these Klebsiella have been identified as one species, ie, K. pneumoniae. However, phenotypic and genotypic studies have shown that “K. pneumoniae” actually consists of at least four species, all with distinct characteristics and habitats. General habitat associations of Klebsiella species are as follows: K. pneumoniae—humans, animals, sewage, and polluted waters and soils; K. oxytoca—frequent association with most habitats; K. terrigena— unpolluted surface waters and soils, drinking water, and vegetation; K. planticola—sewage, polluted surface waters, soils, and vegetation; and K. ozaenae/K. rhinoscleromatis—infrequently detected (primarily with humans).

Keratinocyte growth factor binds to collagens of the gastrointestinal tract: Identification of the collagen binding structure

2001 ◽  
Vol 120 (5) ◽  
pp. A695-A695
Author(s):  
M RUEHL ◽  
I SCHOENFELDER ◽  
R FARNDALE ◽  
G KNIGHT ◽  
R SOMASUNDARAM ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Growth Factor ◽  
Keratinocyte Growth Factor ◽  
Collagen Binding ◽  
Binding Structure
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