scholarly journals The Plasmodium falciparum eIK1 kinase (PfeIK1) is central for melatonin synchronization in the human malaria parasite. Melatotosil blocks melatonin action on parasite cell cycle

2020 ◽  
Vol 69 (3) ◽  
Author(s):  
Bárbara K.M. Dias ◽  
Myna Nakabashi ◽  
Marina Rangel Rodrigues Alves ◽  
Danielle Pagliaminuto Portella ◽  
Benedito Matheus Santos ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Plasmodium Falciparum ◽  
Malaria Parasite ◽  
Human Malaria Parasite ◽  
Human Malaria ◽  
Parasite Cell

scholarly journals Anthracene-Polyamine Conjugates InhibitIn VitroProliferation of Intraerythrocytic Plasmodium falciparum Parasites

2013 ◽  
Vol 57 (6) ◽  
pp. 2874-2877 ◽  
Author(s):  
Jandeli Niemand ◽  
Pieter Burger ◽  
Bianca K. Verlinden ◽  
Janette Reader ◽  
Annie M. Joubert ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Plasmodium Falciparum ◽  
Malaria Parasite ◽  
Human Malaria Parasite ◽  
Content Type ◽  
Human Malaria ◽  
Parasite Cell ◽  
Polyamine Conjugates

ABSTRACTAnthracene-polyamine conjugates inhibit thein vitroproliferation of the intraerythrocytic human malaria parasitePlasmodium falciparum, with 50% inhibitory concentrations (IC50s) in the nM to μM range. The compounds are taken up into the intraerythrocytic parasite, where they arrest the parasite cell cycle. Both the anthracene and polyamine components of the conjugates play a role in their antiplasmodial effect.

Commitment to sexual differentiation in the human malaria parasite, Plasmodium falciparum

Parasitology ◽  
2000 ◽  
Vol 121 (2) ◽  
pp. 127-133 ◽  
Author(s):  
T. G. SMITH ◽  
P. LOURENÇO ◽  
R. CARTER ◽  
D. WALLIKER ◽  
L. C. RANFORD-CARTWRIGHT
Keyword(s):  
Plasmodium Falciparum ◽  
Sexual Differentiation ◽  
Malaria Parasite ◽  
Human Malaria Parasite ◽  
Human Malaria ◽  
Parasite Plasmodium ◽  
Parasite Plasmodium Falciparum
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