Preparation, characterization and preliminary pharmacokinetic study of pH‐sensitive Hydroxyapatite/Zein nano‐drug delivery system for doxorubicin hydrochloride

2020 ◽  
Vol 72 (4) ◽  
pp. 496-506
Author(s):  
Liqiong Zha ◽  
Beilei Wang ◽  
Jiajia Qian ◽  
Brock Fletcher ◽  
Caiyun Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Pharmacokinetic Study ◽  
Ph Sensitive ◽  
Doxorubicin Hydrochloride ◽  
Nano Drug Delivery

A pH-sensitive nano drug delivery system of doxorubicin-conjugated amphiphilic polyrotaxane-based block copolymers

2013 ◽  
Vol 1 (12) ◽  
pp. 1282 ◽  
Author(s):  
Lan Jiang ◽  
Ze-ming Gao ◽  
Lin Ye ◽  
Ai-ying Zhang ◽  
Zeng-guo Feng
Keyword(s):  
Drug Delivery ◽  
Block Copolymers ◽  
Drug Delivery System ◽  
Delivery System ◽  
Ph Sensitive ◽  
Nano Drug Delivery

A pH-sensitive nano drug delivery system derived from pullulan/doxorubicin conjugate

2009 ◽  
Vol 89B (1) ◽  
pp. 177-183 ◽  
Author(s):  
Dianxiang Lu ◽  
Xiantao Wen ◽  
Jie Liang ◽  
Zhongwei Gu ◽  
Xingdong Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Ph Sensitive ◽  
Nano Drug Delivery

scholarly journals Marine Polysaccharides as a Versatile Biomass for the Construction of Nano Drug Delivery Systems

Marine Drugs ◽  
2021 ◽  
Vol 19 (6) ◽  
pp. 345
Author(s):  
Ying Sun ◽  
Xiaoli Ma ◽  
Hao Hu
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Pharmaceutical Preparations ◽  
Utilization Efficiency ◽  
Wound Dressings ◽  
Marine Biomass ◽  
Nano Drug Delivery ◽  
Wide Range ◽  
Marine Polysaccharide

Marine biomass is a treasure trove of materials. Marine polysaccharides have the characteristics of biocompatibility, biodegradability, non-toxicity, low cost, and abundance. An enormous variety of polysaccharides can be extracted from marine organisms such as algae, crustaceans, and microorganisms. The most studied marine polysaccharides include chitin, chitosan, alginates, hyaluronic acid, fucoidan, carrageenan, agarose, and Ulva. Marine polysaccharides have a wide range of applications in the field of biomedical materials, such as drug delivery, tissue engineering, wound dressings, and sensors. The drug delivery system (DDS) can comprehensively control the distribution of drugs in the organism in space, time, and dosage, thereby increasing the utilization efficiency of drugs, reducing costs, and reducing toxic side effects. The nano-drug delivery system (NDDS), due to its small size, can function at the subcellular level in vivo. The marine polysaccharide-based DDS combines the advantages of polysaccharide materials and nanotechnology, and is suitable as a carrier for different pharmaceutical preparations. This review summarizes the advantages and drawbacks of using marine polysaccharides to construct the NDDS and describes the preparation methods and modification strategies of marine polysaccharide-based nanocarriers.

scholarly journals In vitro evaluation of a novel pH sensitive drug delivery system based cockle shell-derived aragonite nanoparticles against osteosarcoma

2017 ◽  
Vol 12 (1) ◽  
pp. 166-187 ◽  
Author(s):  
Wenliang Fu ◽  
Mohd Hezmee Mohd Noor ◽  
Loqman Mohamad Yusof ◽  
Tengku Azmi Tengku Ibrahim ◽  
Yeap Swee Keong ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Ph Sensitive ◽  
In Vitro Evaluation ◽  
Cockle Shell

New in-situ synthetized hydrogel composite based on alginate and brushite as a potential pH sensitive drug delivery system

2017 ◽  
Vol 177 ◽  
pp. 324-333 ◽  
Author(s):  
Seyed Mohammad Hossein Dabiri ◽  
Alberto Lagazzo ◽  
Fabrizio Barberis ◽  
Amirreza Shayganpour ◽  
Elisabetta Finocchio ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Ph Sensitive ◽  
Hydrogel Composite
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