Pharmacological characterization of high‐affinity σ
            1
            receptor ligands with spirocyclic thienopyran and thienofuran scaffold

Dirk Schepmann; Christina Neue; Stefanie Westphälinger; Christoph Müller; Franz Bracher; Carsten Lange; Patrick Bednarski; Carmen Almansa; Kristina Friedland; Vivien Räbiger; Martina Düfer; Bernhard Wünsch

doi:10.1111/jphp.13196

Pharmacological characterization of high‐affinity σ 1 receptor ligands with spirocyclic thienopyran and thienofuran scaffold

Journal of Pharmacy and Pharmacology ◽

10.1111/jphp.13196 ◽

2019 ◽

Vol 72 (2) ◽

pp. 236-248

Author(s):

Dirk Schepmann ◽

Christina Neue ◽

Stefanie Westphälinger ◽

Christoph Müller ◽

Franz Bracher ◽

...

Keyword(s):

Receptor Ligands ◽

Pharmacological Characterization ◽

High Affinity

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Pharmacological Characterization of Novel High Affinity CGRP Receptor Antagonists that are Selective for Human CGRP Receptors

The FASEB Journal ◽

10.1096/fasebj.20.4.a665-a ◽

2006 ◽

Vol 20 (4) ◽

Author(s):

Chrsitopher K. Taylor ◽

D. David Smith ◽

Peter W. Abel

Keyword(s):

Cgrp Receptor ◽

Receptor Antagonists ◽

Pharmacological Characterization ◽

High Affinity ◽

Cgrp Receptor Antagonists

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Pharmacological characterization of F-180: a selective human V1a vasopressin receptor agonist of high affinity

British Journal of Pharmacology ◽

10.1038/sj.bjp.0704634 ◽

2002 ◽

Vol 135 (7) ◽

pp. 1828-1836 ◽

Cited By ~ 21

Author(s):

Miriam Andrés ◽

Miguel Trueba ◽

Gilles Guillon

Keyword(s):

Receptor Agonist ◽

Vasopressin Receptor ◽

Pharmacological Characterization ◽

High Affinity

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Pharmacological Characterization of Human κ / μ Opioid Receptor Chimeras that Retain High Affinity for Dynorphin A

Current Topics in Medicinal Chemistry ◽

10.2174/1568026053544542 ◽

2005 ◽

Vol 5 (3) ◽

pp. 303-313 ◽

Cited By ~ 8

Author(s):

Robert DeHaven ◽

Erik Mansson ◽

Jeffrey Daubert ◽

Joel Cassel

Keyword(s):

Opioid Receptor ◽

Dynorphin A ◽

Pharmacological Characterization ◽

High Affinity ◽

Receptor Chimeras

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ChemInform Abstract: High-Affinity Leukotriene Receptor Antagonists. Synthesis and Pharmacological Characterization of 2-Hydroxy-3-((2-carboxyethyl)thio)-3-(2-(8- phenyloctyl)phenyl)propanoic Acid.

ChemInform ◽

10.1002/chin.198747167 ◽

1987 ◽

Vol 18 (47) ◽

Author(s):

J. G. GLEASON ◽

R. F. HALL ◽

C. D. PERCHONOCK ◽

K. F. ERHARD ◽

J. S. FRAZEE ◽

...

Keyword(s):

Propanoic Acid ◽

Receptor Antagonists ◽

Pharmacological Characterization ◽

High Affinity ◽

Leukotriene Receptor Antagonists ◽

Leukotriene Receptor

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Synthesis and pharmacological characterization of [125I]MRS5127, a high affinity, selective agonist radioligand for the A3 adenosine receptor

Biochemical Pharmacology ◽

10.1016/j.bcp.2009.11.009 ◽

2010 ◽

Vol 79 (7) ◽

pp. 967-973 ◽

Cited By ~ 16

Author(s):

John A. Auchampach ◽

Elizabeth T. Gizewski ◽

Tina C. Wan ◽

Sonia de Castro ◽

Garth G. Brown ◽

...

Keyword(s):

Adenosine Receptor ◽

Pharmacological Characterization ◽

High Affinity ◽

Selective Agonist ◽

A3 Adenosine Receptor

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Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.111.185108 ◽

2011 ◽

Vol 339 (2) ◽

pp. 555-566 ◽

Cited By ~ 37

Author(s):

S. Grimwood ◽

Y. Lu ◽

A. W. Schmidt ◽

M. A. Vanase-Frawley ◽

A. Sawant-Basak ◽

...

Keyword(s):

Opioid Receptors ◽

Pharmacological Characterization ◽

High Affinity

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Pharmacological Characterization of Novel Opioid Receptor Ligands Aimed at Reducing the Development of Tolerance

10.33915/etd.616 ◽

2014 ◽

Author(s):

Jason Randall Healy

Keyword(s):

Opioid Receptor ◽

Receptor Ligands ◽

Pharmacological Characterization ◽

Opioid Receptor Ligands ◽

Development Of Tolerance

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Pharmacological Characterization of 6-Bromo-3â²-nitroflavone, a Synthetic Flavonoid with High Affinity for the Benzodiazepine Receptors

Pharmacology Biochemistry and Behavior ◽

10.1016/s0091-3057(98)00088-4 ◽

1998 ◽

Vol 61 (3) ◽

pp. 239-246 ◽

Cited By ~ 14

Author(s):

C Wolfman

Keyword(s):

Benzodiazepine Receptors ◽

Pharmacological Characterization ◽

High Affinity

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Pharmacological characterization of high affinity choline transporters in primary neuronal cultures in rat brain

Neuropharmacology ◽

10.1016/0028-3908(88)90100-1 ◽

1988 ◽

Vol 27 (8) ◽

pp. 837-842 ◽

Cited By ~ 7

Author(s):

M KELLEY ◽

M RAIZADA ◽

E MEYER

Keyword(s):

Rat Brain ◽

Neuronal Cultures ◽

Primary Neuronal Cultures ◽

Pharmacological Characterization ◽

High Affinity

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Pharmacological characterization of benzodiazepine receptor ligands with intrinsic efficacies ranging from high to zero

Psychopharmacology ◽

10.1007/bf02253530 ◽

1993 ◽

Vol 111 (4) ◽

pp. 415-422 ◽

Cited By ~ 41

Author(s):

James R. Martin ◽

Peter Schoch ◽

François Jenck ◽

Jean-Luc Moreau ◽

Willy E. Haefely

Keyword(s):

Benzodiazepine Receptor ◽

Receptor Ligands ◽

Pharmacological Characterization ◽

Benzodiazepine Receptor Ligands

Download Full-text

Pharmacological characterization of high‐affinity σ 1 receptor ligands with spirocyclic thienopyran and thienofuran scaffold

Pharmacological Characterization of Novel High Affinity CGRP Receptor Antagonists that are Selective for Human CGRP Receptors

Pharmacological characterization of F-180: a selective human V1a vasopressin receptor agonist of high affinity

Pharmacological Characterization of Human κ / μ Opioid Receptor Chimeras that Retain High Affinity for Dynorphin A

ChemInform Abstract: High-Affinity Leukotriene Receptor Antagonists. Synthesis and Pharmacological Characterization of 2-Hydroxy-3-((2-carboxyethyl)thio)-3-(2-(8- phenyloctyl)phenyl)propanoic Acid.

Synthesis and pharmacological characterization of [125I]MRS5127, a high affinity, selective agonist radioligand for the A3 adenosine receptor

Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors

Pharmacological Characterization of Novel Opioid Receptor Ligands Aimed at Reducing the Development of Tolerance

Pharmacological Characterization of 6-Bromo-3â²-nitroflavone, a Synthetic Flavonoid with High Affinity for the Benzodiazepine Receptors

Pharmacological characterization of high affinity choline transporters in primary neuronal cultures in rat brain

Pharmacological characterization of benzodiazepine receptor ligands with intrinsic efficacies ranging from high to zero

Pharmacological Characterization of 6-Bromo-3â²-nitroflavone, a Synthetic Flavonoid with High Affinity for the Benzodiazepine Receptors