Distinct effects of novel naphtoquinone-based triazoles in human leukaemic cell lines

2015 ◽  
Vol 67 (12) ◽  
pp. 1682-1695 ◽  
Author(s):  
Tangbadioa H. Coulidiati ◽  
Bruna B. Dantas ◽  
Glaucia V. Faheina-Martins ◽  
Juan C. R. Gonçalves ◽  
Wilson S. do Nascimento ◽  
...  
Keyword(s):  
Cell Lines ◽  
Leukaemic Cell

The nuclear 3,5,3'-triiodothyronine receptor in human leukaemic cell lines

1984 ◽  
Vol 105 (3) ◽  
pp. 429-432 ◽  
Author(s):  
Juan Bernal ◽  
Leif C. Andersson
Keyword(s):  
Growth Hormone ◽  
Cell Line ◽  
Cell Lines ◽  
Rat Liver ◽  
Association Constant ◽  
Erythroid Differentiation ◽  
Leukaemic Cell ◽  
Cells In Culture ◽  
Gh Cells ◽  
High Concentrations

Abstract. The 3,5,3'-triiodothyronine (T3) receptor has been studied in a series of continuously growing human leukaemic cell lines. High concentrations of receptor were found in the erythroblastoid cell line K-562. T3 was bound to the nuclei of these cells with an association constant of 3.4 × 109 m−1, and capacity 104 fmol/100 μg DNA, or 8700 molecules/nucleus. This capacity is comparable to that of rat liver or growth hormone producing cells (GH cells) in culture, and suggests that the K-562 cell line could be a useful model for the study of T3 action on erythroid differentiation.

Antimicrotubule agents induce polyploidization of human leukaemic cell lines with megakaryocytic features

1993 ◽  
Vol 23 (10) ◽  
pp. 621-629 ◽  
Author(s):  
B. VAN DER LOO ◽  
Y. HONG ◽  
V. HANCOCK ◽  
J. F. MARTIN ◽  
J. D. ERUSALIMSKY
Keyword(s):  
Cell Lines ◽  
Leukaemic Cell ◽  
Antimicrotubule Agents

Release of Platelet-Activating Factor from Human Leukaemic Cell Lines

1984 ◽  
pp. 691-694
Author(s):  
R. FOÀ ◽  
F. MALAVASI ◽  
F. BUSSOLINO ◽  
M.C. FERRANDO ◽  
C. TETTA ◽  
...  
Keyword(s):  
Cell Lines ◽  
Platelet Activating Factor ◽  
Leukaemic Cell

Inside Cover: Syringolin A Selectively Labels the 20 S Proteasome in Murine EL4 and Wild-Type and Bortezomib-Adapted Leukaemic Cell Lines (ChemBioChem 16/2009)

ChemBioChem ◽  
2009 ◽  
Vol 10 (16) ◽  
pp. 2546-2546
Author(s):  
Jérôme Clerc ◽  
Bogdan I. Florea ◽  
Marianne Kraus ◽  
Michael Groll ◽  
Robert Huber ◽  
...  
Keyword(s):  
Cell Lines ◽  
Leukaemic Cell ◽  
Wild Type

scholarly journals Determination of the Effects of Camptothecin on Cell Cycling and Apoptosis in Human Leukaemic Cell Lines

2001 ◽  
Vol 1 ◽  
pp. 105-105 ◽  
Author(s):  
Anne Cox ◽  
Dawn A. Bradbury ◽  
Tracy D. Simmons ◽  
Kevin J. Slater ◽  
Sharon P. M. Crouch
Keyword(s):  
Cell Lines ◽  
Leukaemic Cell ◽  
Cell Cycling

Fruit Extract from ASechium eduleHybrid Induce Apoptosis in Leukaemic Cell Lines but not in Normal Cells

2015 ◽  
Vol 67 (2) ◽  
pp. 250-257 ◽  
Author(s):  
Itzen Aguiñiga-Sánchez ◽  
Marcos Soto-Hernández ◽  
Jorge Cadena-Iñiguez ◽  
Lucero del Mar Ruíz-Posadas ◽  
Jorge David Cadena-Zamudio ◽  
...  
Keyword(s):  
Cell Lines ◽  
Leukaemic Cell ◽  
Fruit Extract ◽  
Normal Cells

A novel bioluminescent bacterial biosensor for measurement of Ara-CTP and cytarabine potentiation by fludarabine in seven leukaemic cell lines

2013 ◽  
Vol 37 (6) ◽  
pp. 690-696 ◽  
Author(s):  
Elizabeth Anderson ◽  
M. Ann Smith ◽  
Ashley Martin ◽  
Mark Ruddock ◽  
John Lamont ◽  
...  
Keyword(s):  
Cell Lines ◽  
Leukaemic Cell ◽  
Bacterial Biosensor

The accumulation of [35S]methimazole by monocytes and macrophages

1984 ◽  
Vol 107 (3) ◽  
pp. 366-370 ◽  
Author(s):  
A. P. Weetman ◽  
Catherine Gunn ◽  
R. Hall ◽  
A. M. McGregor
Keyword(s):  
Cell Lines ◽  
Antithyroid Drug ◽  
Antigen Presenting Cells ◽  
Leukaemic Cell ◽  
Graves Disease ◽  
Temperature Dependent ◽  
Culture Techniques ◽  
Monocytes And Macrophages ◽  
Significant Temperature ◽  
Antigen Presenting

Abstract. We have used an automatic cell harvester and micro culture techniques to examine the accumulation of [35S]methimazole by monocytes, macrophages and lymphocytes. Significant temperature-dependent accumulation of the drug was found in resting monocytes and macrophages; this was increased up to 4-fold by phagocytosis. Lymphocytes accumulated little or no drug and myeloma and leukaemic cell lines accumulated none. These results show that two interrelated cells with endogenous peroxidatic activity take up the antithyroid drug methimazole providing further support for the concept that immunosuppression by this drug in Graves' disease is mediated via an action on antigen-presenting cells.

Sign in / Sign up

Export Citation Format

Share Document