scholarly journals Relationship of chest computed tomography score with disease severity and laboratory values in children with COVID ‐19

2021 ◽  
Author(s):  
Ceren Çetin ◽  
Ayse Karaaslan ◽  
Yasemin Akın ◽  
Meral Arifoglu ◽  
Günay Rona ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Disease Severity ◽  
Chest Computed Tomography ◽  
Laboratory Values ◽  
Relationship Of

scholarly journals Evaluation of the Prognostic Value of Chest Computed Tomography (CT) Scan in COVID-19 Patients

2021 ◽  
Vol 18 (2) ◽  
Author(s):  
Behzad Aminzadeh ◽  
Parvaneh Layegh ◽  
Mahdi Foroughian ◽  
Ahmadreza Tavassoli ◽  
Maryam Emadzadeh ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Disease Severity ◽  
Roc Curve ◽  
Prognostic Value ◽  
Imaging Features ◽  
Scoring Methods ◽  
Chest Computed Tomography ◽  
Prediction Of Mortality ◽  
Significant Difference ◽  
Hospital Wards

Objectives: To evaluate the prognostic value of chest computed tomography (CT) imaging features in patients with coronavirus disease 2019 (COVID-19) pneumonia. Methods: In this cross-sectional study, 201 patients with COVID-19 were enrolled consecutively. The patients’ chest CT scans were analyzed, and the disease severity was rated using two methods: (1) total lung involvement (TLI) in which each lobe is scored from 0 to 4 based on the percentage of involvement; and (2) modified TLI in which each lobe involvement score is multiplied by the number of its segments, and the sum is recorded as the modified TLI. The patients were categorized into four groups depending on their prognosis (patients admitted to hospital wards, patients admitted to intensive care units (ICUs), patients with intubation during hospitalization, and expired patients). The relationship between both scoring methods and the clinical outcomes of patients was examined in the four groups. Results: The receiver operating characteristic (ROC) curve analysis showed no significant difference between the two scoring methods (TLI and modified TLI) in predicting the patients’ prognosis. The average disease severity based on the two scoring methods was significantly different between the four groups. Patients who were intubated during hospitalization and patients who expired had significantly higher scores than patients admitted to the ICUs and hospital wards (P = 0.001). The area under the ROC curve for the prediction of mortality was 0.81 (95% CI: 0.72 - 0.90; P < 0.001); the TLI score of 18.5 could predict mortality with specificity of > 95%. Conclusions: The TLI scoring system can be used for predicting in-hospital mortality and ICU admission in COVID-19 patients. This scoring method can help us devise a better strategic healthcare plan during the COVID-19 pandemic.

scholarly journals Could Chest Computed Tomography Scores Assess the Inflammatory Markers and Disease Severity of Coronavirus Disease-2019 Patients?

2021 ◽  
Vol 11 (1) ◽  
pp. 62-68
Author(s):  
Yasemin Kayadibi ◽  
Neşe Uçar ◽  
Mehmet Fatih Kaya ◽  
Okan Gürkan ◽  
Yeşim Namdar Akan ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Disease Severity ◽  
Inflammatory Markers ◽  
Chest Computed Tomography

COMPARATIVE DOSIMETRIC STUDY IN CHEST COMPUTED TOMOGRAPHY USING PHANTOMS

2019 ◽  
Vol 7 (1A) ◽  
Author(s):  
Wadia Aburjaile ◽  
Mauricio Gomez ◽  
Arnaldo Prata Mourão
Keyword(s):  
Computed Tomography ◽  
Chest Computed Tomography ◽  
Dosimetric Study

scholarly journals Pulmonary coinfection of Mycobacterium tuberculosis and Tropheryma whipplei: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Binghua Zhu ◽  
Jing Tang ◽  
Rong Fang ◽  
Xuejie Fei ◽  
Qing Wang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Mycobacterium Tuberculosis ◽  
Next Generation Sequencing ◽  
Tropheryma Whipplei ◽  
Diagnostic Methods ◽  
Next Generation ◽  
Computed Tomography Scan ◽  
Chest Computed Tomography ◽  
Tomography Scan ◽  
Generation Sequencing

Abstract Background We diagnosed a clinical case of pulmonary infection involving Mycobacterium tuberculosis and Tropheryma whipplei in a patient with acute respiratory distress syndrome. The diagnosis was assisted by metagenomic next-generation sequencing of bronchoalveolar lavage fluid. Case presentation A 44-year-old Han Chinese inmate was transferred to the emergency department because of dry cough, chest tightness, and shortness of breath. The patient’s body temperature rose to 39.3 °C following empirical cephalosporin treatment for 1 week. The blood CD4+/CD8+ ratio was 0.7, suggesting immunodeficiency. Routine microbiological tests were performed, and tuberculosis interferon gamma release assays were positive. Mycobacterium tuberculosis polymerase chain reaction was also positive. Chest computed tomography scan revealed miliary nodules and ground-glass opacifications, which were in accordance with tuberculosis. To fully examine the etiology, we performed routine laboratory tests and metagenomic sequencing, the results of which indicated the presence of Mycobacterium tuberculosis and Tropheryma whipplei. We administered anti-tuberculosis regimen in combination with trimethoprim/sulfamethoxazole. The patient recovered, with chest computed tomography scan showing absorption of lesions. Conclusions Compared with traditional diagnostic methods such as culture and serology, metagenomic next-generation sequencing has the advantage of detecting a wide array of microorganisms in a single test and therefore can be used for clinical diagnosis of rare pathogens and microbial coinfections. It is particularly useful for immunocompromised patients as they are more prone to infection by opportunistic microorganisms.

scholarly journals SARS-CoV-2 infection in an infant with non-respiratory manifestations: a case report

2021 ◽  
Vol 69 (1) ◽  
Author(s):  
Muhammad Adel ◽  
Ahmed Magdy
Keyword(s):  
Computed Tomography ◽  
Aplastic Anemia ◽  
Rt Pcr ◽  
Positive Real ◽  
Case Presentation ◽  
Chest Computed Tomography ◽  
High Incidence ◽  
Laboratory Investigations ◽  
High Index Of Suspicion ◽  
Specific Symptoms

Abstract Background Coronavirus disease (COVID-19) presents in children usually with less severe manifestations than in adults. Although fever and cough were reported as the most common symptoms, children can have non-specific symptoms. We describe an infant with aplastic anemia as the main manifestation. Case presentation We describe a case of SARS-CoV-2 infection in an infant without any respiratory symptoms or signs while manifesting principally with pallor and purpura. Pancytopenia with reticulocytopenia was the predominant feature in the initial laboratory investigations, pointing to aplastic anemia. Chest computed tomography surprisingly showed typical findings suggestive of SARS-CoV-2 infection. Infection was later confirmed by positive real-time reverse transcription polymerase chain reaction assay (RT-PCR) for SARS-CoV-2. Conclusions Infants with COVID-19 can have non-specific manifestations and a high index of suspicion should be kept in mind especially in regions with a high incidence of the disease. Chest computed tomography (CT) and testing for SARS-CoV-2 infection by RT-PCR may be considered even in the absence of respiratory manifestations.

scholarly journals Airway Foreign Body Mimicking an Endobronchial Tumor Presenting with Pneumothorax in an Adult: A Case Report

Medicina ◽  
2021 ◽  
Vol 57 (1) ◽  
pp. 50
Author(s):  
Jun-Ho Ha ◽  
Byeong-Ho Jeong
Keyword(s):  
Computed Tomography ◽  
Foreign Body ◽  
Chest Tube ◽  
Biopsy Forceps ◽  
Chest Computed Tomography ◽  
Contrast Enhanced ◽  
Lobar Bronchus ◽  
Green Pea ◽  
Airway Foreign Body ◽  
The Right

Foreign body (FB) aspiration occurs less frequently in adults than in children. Among the complications related to FB aspiration, pneumothorax is rarely reported in adults. Although the majority of FB aspiration cases can be diagnosed easily and accurately by using radiographs and bronchoscopy, some patients are misdiagnosed with endobronchial tumors. We describe a case of airway FB that mimicked an endobronchial tumor presenting with pneumothorax in an adult. A 77-year-old man was referred to our hospital due to pneumothorax and atelectasis of the right upper lobe caused by an endobronchial nodule. A chest tube was immediately inserted to decompress the pneumothorax. Chest computed tomography with contrast revealed an endobronchial nodule that was seen as contrast-enhanced. Flexible bronchoscopy was performed to biopsy the nodule. The bronchoscopy showed a yellow spherical nodule in the right upper lobar bronchus. Rat tooth forceps were used, because the lesion was too slippery to grasp with ellipsoid cup biopsy forceps. The whole nodule was extracted and was confirmed to be a FB, which was determined to be a green pea vegetable. After the procedure, the chest tube was removed, and the patient was discharged without any complications. This case highlights the importance of suspecting a FB as a cause of pneumothorax and presents the possibility of misdiagnosing an aspirated FB as an endobronchial tumor and selecting the appropriate instrument for removing an endobronchial FB.

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