scholarly journals Ten years of severe respiratory syncytial virus infections in a tertiary paediatric intensive care unit

2019 ◽  
Vol 56 (1) ◽  
pp. 61-67 ◽  
Author(s):  
Hiep Pham ◽  
Jenny Thompson ◽  
Danielle Wurzel ◽  
Trevor Duke
2020 ◽  
Vol 48 (9) ◽  
pp. 982-986
Author(s):  
Andreu Comas-García ◽  
José I. Aguilera-Martínez ◽  
Francisco J. Escalante-Padrón ◽  
Victoria Lima-Rogel ◽  
Luis M. Gutierrez-Mendoza ◽  
...  

2016 ◽  
Vol 3 (suppl_1) ◽  
Author(s):  
Yoshiaki Cho ◽  
Takemi Murai ◽  
Yukitsugu Nakamura ◽  
Takayuki Yamanaka ◽  
Kahoru Fukuoka ◽  
...  

2009 ◽  
Vol 19 (4) ◽  
pp. 346-351 ◽  
Author(s):  
Alastair Turner ◽  
Colin Begg ◽  
Benjamin Smith ◽  
Jonathan Coutts

AbstractObjectivesTo describe the pattern of prescribing for palivizumab in the Glasgow area over the period 1999 through 2007, and to compare recent prescribing to the current recommendations by the Joint Committee on Vaccination and Immunisation of the United Kingdom Department of Health. Our secondary objective was to describe admissions to paediatric intensive care in patients with respiratory syncytial virus receiving palivizumab.SettingTertiary children’s hospital out-patient immunisation clinic and paediatric intensive care unit.DesignProspective analysis of prescribing and admissions data for the period 1999 through 2007.Outcome measuresNumber of prescriptions and admissions to the paediatric intensive care unit.ResultsThe number of children receiving palivizumab annually initially rose more than 5-fold, from 17 in the season of 1999 and 2000 versus 115 in 2004 and 2005, although it has declined in the past 2 years, to 63 in 2006 and 2007, following publication of the recommendations of the Joint Committee on Vaccination and Immunisation established by the United Kingdom Department of Health. There has been no significant change in demographics of patients during this period. Prior to publication of these recommendations, 35 of 44 (80%) patients with congenitally malformed hearts who received palivizumab in the season of 2005 and 2006 deviated from the current recommendations, compared to 5 of 51 (10%) who received palivizumab for non-cardiac indications. No patients who received palivizumab required admission to the paediatric intensive care unit with proven respiratory syncytial virus infection over the 8 year period.ConclusionsThe number of children receiving palivizumab initially increased significantly, although it has now fallen following implementation of national recommendations. Much prescribing, particularly for children with congenitally malformed hearts, did not fulfil current recommendations. The absence of admissions to paediatric intensive care reflects the success of targeted immunisation in our population.


PEDIATRICS ◽  
1979 ◽  
Vol 64 (2) ◽  
pp. 149-153
Author(s):  
Lawrence Mintz ◽  
Roberta A. Ballard ◽  
Susan H. Sniderman ◽  
Robert S. Roth ◽  
W. Lawrence Drew

A nosocomial outbreak of respiratory syncytial virus infections involved 8 of 17 infants in an Intensive Care Nursery and one additional infant in the adjoining Newborn Nursery. Immunofluorescent staining of nasopharyngeal specimens was positive in six of seven virologically confirmed cases (86%). One additional case with negative viral cultures was also identified by this technique. Viral isolation in tissue cultures required an average of 4.9 days, whereas results of immunofluorescent studies were available in two to four hours. Rapid identification of infected infants by immunofluorescence permitted prompt institution of infection control measures.


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