scholarly journals Infant wheeze: Is asthma a possibility?

2013 ◽  
Vol 49 (12) ◽  
pp. 991-994 ◽  
Author(s):  
Philip K Pattemore
Keyword(s):  
Infant Wheeze

Environmental Relative Moldiness Index and Associations with Home Characteristics and Infant Wheeze

2014 ◽  
Vol 12 (1) ◽  
pp. 29-36 ◽  
Author(s):  
P. F. Rosenbaum ◽  
J. A. Crawford ◽  
A. Hunt ◽  
S. J. Vesper ◽  
J. L. Abraham
Keyword(s):  
Infant Wheeze

Infant Wheeze, Comorbidities and School Age Asthma

PEDIATRICS ◽  
2015 ◽  
Vol 136 (Supplement) ◽  
pp. S232-S233
Author(s):  
T. Grant ◽  
E. Matsui
Keyword(s):  
School Age ◽  
Infant Wheeze

Infant wheeze, comorbidities and school age asthma

2014 ◽  
Vol 25 (4) ◽  
pp. 380-386 ◽  
Author(s):  
Åsa Neuman ◽  
Anna Bergström ◽  
Per Gustafsson ◽  
Per Thunqvist ◽  
Niklas Andersson ◽  
...  
Keyword(s):  
School Age ◽  
Infant Wheeze

scholarly journals Effects of a 17q21 chromosome gene variant, tobacco smoke and furred pets on infant wheeze

2011 ◽  
Vol 13 (1) ◽  
pp. 94-97 ◽  
Author(s):  
E V Bräuner ◽  
S Loft ◽  
O Raaschou-Nielsen ◽  
U Vogel ◽  
P S Andersen ◽  
...  
Keyword(s):  
Tobacco Smoke ◽  
Gene Variant ◽  
Chromosome Gene ◽  
Infant Wheeze

scholarly journals Maternal Fiber Dietary Intakes during Pregnancy and Infant Allergic Disease

Nutrients ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1767 ◽  
Author(s):  
Rachelle A. Pretorius ◽  
Marie Bodinier ◽  
Susan L. Prescott ◽  
Debra J. Palmer
Keyword(s):  
Allergic Disease ◽  
Resistant Starch ◽  
Skin Prick Testing ◽  
Maternal Diet ◽  
Dietary Intakes ◽  
Soluble Fiber ◽  
Increased Risk ◽  
History Of ◽  
Infant Wheeze ◽  
Prebiotic Fiber

Maternal diet during pregnancy plays a likely role in infant immune development through both direct nutrient specific immunomodulatory effects and by modulating the composition and metabolic activity of the maternal gut microbiome. Dietary fibers, as major substrates for microbial fermentation, are of interest in this context. This is the first study to examine maternal intakes of different fiber sub-types and subsequent infant allergic disease. In an observational study of 639 mother–infant pairs (all infants had a family history of allergic disease) we examined maternal intakes of total fiber, soluble fiber, insoluble fiber, resistant starch, and prebiotic fiber, by a semi-quantitative food frequency questionnaire at 36–40 weeks’ gestation. Infants attended an allergy clinical assessment at 12 months of age, including skin prick testing to common allergens. Higher maternal dietary intakes of resistant starch were associated with reduced doctor diagnosed infant wheeze, adjusted odds ratio (aOR) 0.68 (95% CI 0.49, 0.95, p = 0.02). However, in contrast, higher maternal intakes of resistant starch were associated with higher risk of parent reported eczema aOR 1.27 (95% CI 1.09, 1.49, p < 0.01) and doctor diagnosed eczema aOR 1.19 (95% CI 1.01, 1.41, p = 0.04). In conclusion, maternal resistant starch consumption was differentially associated with infant phenotypes, with reduced risk of infant wheeze, but increased risk of eczema.

scholarly journals Association Between Neonatal Gut Microbiome and Infant Wheeze

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Aileen E. Seay ◽  
Sydney E. Ross ◽  
Christopher M. Hemmerich ◽  
Douglas B. Rusch ◽  
Kirsten M. Kloepfer
Keyword(s):  
Early Childhood ◽  
Statistical Analysis ◽  
Gut Microbiome ◽  
Pulmonary Function Tests ◽  
Rrna Gene ◽  
Targeted Interventions ◽  
Gut Dysbiosis ◽  
Shannon Diversity ◽  
Significant Difference ◽  
Infant Wheeze

Background: Asthma is a chronic respiratory disease that affects 10% of children. Infant wheeze at 1 year and the subsequent development of asthma in early childhood has been associated with infant gut dysbiosis. However, little is known about the relationship between neonatal gut microbiome and the development of wheeze during the first 18 months of life. We hypothesize that the gut microbiome at birth and throughout the first 18 months of life is associated with infant wheeze.  Project Methods: Stool samples were collected from infants at birth, 1, 3, and 12 months of age. The Illumina Miseq system was used to sequence the bacterial V4 region of 16S-rRNA gene. Mothur software was used for analysis. Statistical analysis was used to measure stool shannon diversity and evenness as they relate to timepoint and wheeze vs no wheeze groups.  Results: The study population consisted of 28 infants (18 males and 10 females). 11% of participants reported they had been diagnosed with wheeze by a physician (n=3). Statistical analysis of shannon diversity showed no differences in the stool between participants who wheeze vs those who do not wheeze (p=0.78). No difference in stool evenness was detected between participants who reported wheeze vs no wheeze (p=0.71). However, this analysis includes multiple timepoints. Analysis of stool shannon diversity across timepoints did show a significant difference in stool microbiome (p=0.01).  Conclusion: No differences in stool microbiome were found between infants who do not wheeze and those who do. Further studies can investigate a greater number of samples at each timepoint and relate these to objective measures such as pulmonary function tests. Understanding the association between infant gut dysbiosis and wheeze could have implications for predicting development of asthma in early childhood and potentially lead to targeted interventions. 

Differential effects of risk factors on infant wheeze and atopic dermatitis emphasize a different etiology

2006 ◽  
Vol 117 (1) ◽  
pp. 184-189 ◽  
Author(s):  
A LINNEBERG ◽  
J SIMONSEN ◽  
J PETERSEN ◽  
L STENSBALLE ◽  
C BENN
Keyword(s):  
Risk Factors ◽  
Atopic Dermatitis ◽  
Differential Effects ◽  
Infant Wheeze

Maternal employment in child-care institutions and the risk of infant wheeze and atopic dermatitis in the offspring

2008 ◽  
Vol 19 (8) ◽  
pp. 688-695 ◽  
Author(s):  
Lars-Georg Hersoug ◽  
Christine S. Benn ◽  
Jacob B. Simonsen ◽  
Mads Kamper-Jørgensen ◽  
Allan Linneberg
Keyword(s):  
Atopic Dermatitis ◽  
Child Care ◽  
Maternal Employment ◽  
Infant Wheeze ◽  
Child Care Institutions
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