COMPARISON OF Kt/V AND UREA REDUCTION RATIO IN MEASURING DIALYSIS ADEQUACY IN PAEDIATRIC HAEMODIALYSIS IN ENGLAND

2014 ◽  
Vol 40 (2) ◽  
pp. 117-124 ◽  
Author(s):  
Nina Dunne ◽  
Malcolm Campbell ◽  
Maggie Fitzpatrick ◽  
Peter Callery
Keyword(s):  
Reduction Ratio ◽  
Dialysis Adequacy ◽  
Paediatric Haemodialysis ◽  
Urea Reduction Ratio

scholarly journals Quality of Life and Sleep Disorders Among Patients Treated with Hemodialysis in Relation to Dialysis Adequacy

2014 ◽  
Vol 124 (3) ◽  
pp. 111-114
Author(s):  
Teresa Dryl-Rydzyńska ◽  
Jarosław Sak ◽  
Andrzej Książek
Keyword(s):  
Quality Of Life ◽  
Sleep Disorders ◽  
Reduction Ratio ◽  
Dialysis Adequacy ◽  
Urea Level ◽  
Sf 36 ◽  
Quality Of Life Scale ◽  
The Relationship ◽  
Urea Reduction Ratio

Abstract Introduction. Recent studies in this field are insufficient to determine the relationship between life quality and hemodialy-sis adequacy. The problem, which requires further analysis is the issue of verification of these relationships and the problem of the relationship between sleep disorders and hemodialysis indicators. Aim. The aim of this study is to determine the relationship between quality of life and sleep disorders occurring among patients with end stage renal disease (ESRD) treated with hemodialysis and the dialysis adequacy parameters. Material and methods. The survey was based on two standardized international scales: the Quality of Life Scale (SF-36) and the Pittsburg Sleep Quality Index (PSQI). The study was conducted among 150 patients (67 women and 83 men) treated with hemodialysis at the Fresenius center. All patients participating in the study were undergoing dialysis three times a week. The average value of Kt/V was 1.45 (SD=0.22) and URR ration 71.78 (SD=5.95). Results. The urea level prior to hemodialysis moderately strongly correlates with life energy deficit (r=-0.34, p=-0.049) and that the values of urea reduction ratio URR weakly correlates with the patient's conviction on restricting life's activity (SF-36) (r=0.18, p=0.046). The level of urea prior to dialysis correlates positively with the time of falling asleep in PSQI scale (r=-0.39, p=0.023). Conclusions. Patients with lower urea level before hemodialysis have a significantly higher vitality level. Higher fluctuations of urea concentrations before and after hemodialysis (higher urea reduction ratio URR) are associated with restrictions of physical activity in hemodialysis patients.

scholarly journals Determination of the delivered hemodialysis dose using standard methods and on-line clearance monitoring

2006 ◽  
Vol 63 (8) ◽  
pp. 743-747 ◽  
Author(s):  
Vlastimir Vlatkovic ◽  
Biljana Stojimirovic
Keyword(s):  
Cumulative Effect ◽  
Chronic Hemodialysis ◽  
Reduction Ratio ◽  
The Other ◽  
Treatment Quality ◽  
Monitoring Methods ◽  
Dialysis Dose ◽  
Co Morbidity ◽  
On Line ◽  
Urea Reduction Ratio

Background/aim: Delivered dialysis dose has a cumulative effect and significant influence upon the adequacy of dialysis, quality of life and development of co-morbidity at patients on dialysis. Thus, a great attention is given to the optimization of dialysis treatment. On-line Clearance Monitoring (OCM) allows a precise and continuous measurement of the delivered dialysis dose. Kt/V index (K = dialyzer clearance of urea; t = dialysis time; V = patient's total body water), measured in real time is used as a unit for expressing the dialysis dose. The aim of this research was to perform a comparative assessment of the delivered dialysis dose by the application of the standard measurement methods and a module for continuous clearance monitoring. Methods. The study encompassed 105 patients who had been on the chronic hemodialysis program for more than three months, three times a week. By random choice, one treatment per each controlled patient was taken. All the treatments understood bicarbonate dialysis. The delivered dialysis dose was determined by the calculation of mathematical models: Urea Reduction Ratio (URR) singlepool index Kt/V (spKt/V) and by the application of OCM. Results. Urea Reduction Ratio was the most sensitive parameter for the assessment and, at the same time, it was in the strongest correlation with the other two, spKt/V indexes and OCM. The values pointed out an adequate dialysis dose. The URR values were significantly higher in women than in men, p < 0.05. The other applied model for the delivered dialysis dose measurement was Kt/V index. The obtained values showed that the dialysis dose was adequate, and that, according to this parameter, the women had significantly better dialysis, then the men p < 0.05. According to the OCM, the average value was slightly lower than the adequate one. The women had a satisfactory dialysis according to this index as well, while the delivered dialysis dose was insufficient in men. The difference between the women and the men was significant. Conclusion. The application of OCM has shown that it is the most rigorous parameter for the assessment of adequacy and that its regular use would contribute to increasing of the delivered dialysis dose and improvement of the treatment quality.

scholarly journals Effect Of Surface Area Of Dialyzer Membrane On The Adequacy Of Haemodialysis

2012 ◽  
Vol 7 (2) ◽  
pp. 9-11 ◽  
Author(s):  
NS Chowdhury ◽  
FMM Islam ◽  
F Zafreen ◽  
BA Begum ◽  
N Sultana ◽  
...  
Keyword(s):  
Renal Disease ◽  
Surface Area ◽  
End Stage Renal Disease ◽  
Membrane Surface ◽  
Reduction Ratio ◽  
Urea Clearance ◽  
Membrane Surface Area ◽  
Stage Renal Disease ◽  
End Stage ◽  
Urea Reduction Ratio

Introduction: Patients with end stage renal disease require 12 hours of haemodialysis per week in three equal sessions (4 hours/day for 3 days/week). But the duration and frequency of treatment can be reduced by increasing the surface area of the dialyzer membrane. Methods: In this prospective study 40 patients of end stage renal disease receiving haemodialysis for more than six months were included to observe the effects of increment in the surface area of the dialyzer membrane on the adequacy of haemodialysis. Result: It was observed that 20 patients receiving haemodialysis on a dialyzer with membrane surface area of 1.2 m² did not have satisfactory solute clearance index. Urea reduction ratio was 45.9 ± 3.03 and fractional urea clearance (Kt/V) was 0.76 ± 0.09. On the other hand patients (20 cases) receiving haemodialysis on a dialyzer with membrane surface area of 1.3 m² had a urea reduction ratio 50.76± 5.16 and fractional urea clearance (Kt/V) 0.91 ± 0.16. All the patients of both groups received dialysis for 8 hours/week in two equal sessions (4 hours/day for 2 days/week). Statistically the increment was significant (p<0.001). Conclusion: This study reveals, adequacy of dialysis can be increased by increasing the surface area of the dialyzer membrane. So, considering the poor socioeconomic condition of Bangladesh and patients' convenience, a short duration, low cost dialysis regime can be tried by increasing the surface area of dialyzer membrane. DOI: http://dx.doi.org/10.3329/jafmc.v7i2.10387 JAFMC 2011; 7(2): 9-11

scholarly journals Adequacy of Hemodialysis and Its Associated Factors among Patients Undergoing Chronic Hemodialysis in Dar es Salaam, Tanzania

2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Samina S. Somji ◽  
Pascal Ruggajo ◽  
Sibtain Moledina
Keyword(s):  
Multivariate Analysis ◽  
Surface Area ◽  
Associated Factors ◽  
Univariate Analysis ◽  
Reduction Rate ◽  
Dar Es Salaam ◽  
Chronic Hemodialysis ◽  
Reduction Ratio ◽  
Hemodialysis Dose ◽  
Urea Reduction Ratio

The worldwide prevalence of maintenance hemodialysis continues to rise. An adequate delivery of hemodialysis dose as measured by Kt/V or urea reduction ratio is a crucial determinant of clinical outcome for chronic hemodialysis patients. The aim of this study was to assess the adequacy of hemodialysis and its associated factors among patients undergoing chronic hemodialysis in Dar es Salaam. This was a cross-sectional study done on patients undergoing chronic hemodialysis in four dialysis centers in Dar es Salaam. Sociodemographic information and treatment characteristics were collected. Urea reduction rate and single-pool Kt/V were calculated to determine the adequacy of hemodialysis. The data were analyzed and any associated factors for inadequate hemodialysis were determined using a chi-square test and a logistic regression analysis. A total of 143 patients participated in the study. Males represented 65.7% of the study population. The mean age (±SD) was 51.7 ± 1.2 years. Only 34.3% (based on urea reduction ratio (URR)) and 40.6% (based on Kt/V) of patients received adequate hemodialysis. The univariate analysis showed that males were more likely to have inadequate dialysis (65.6% versus 48.0%, p=0.048 based on Kt/V). Patients using hemodialyzers with dialyzer surface area less than 1.4 m2 received significantly less hemodialysis dose than those with more than 1.4 m2 (69.0% versus 41.2%, p=0.02, by URR) (62.7% versus 35.3%, p=0.03, by Kt/V criteria). Patients who had hemoglobin <10 g/dl received significantly inadequate hemodialysis dose as compared to patients with hemoglobin ≥10 g/dl by Kt/V criteria (69.8% versus 51.3%, p=0.03). None of the factors acquired significance in the multivariate analysis. The proportion of patients receiving an adequate hemodialysis dose is low (34.3% based on URR and 40.6% based on Kt/V). Male gender, dialyzer surface area of <1.4 m2, and hemoglobin level of <10 g/dl were associated with an inadequate delivered dose of hemodialysis in the univariate analysis but not in the multivariate analysis. This study can increase awareness about the importance of measuring hemodialysis adequacy and giving the correct hemodialysis dose to achieve the intended benefit.

scholarly journals Exploring the reverse J-shaped curve between urea reduction ratio and mortality

1999 ◽  
Vol 56 (5) ◽  
pp. 1872-1878 ◽  
Author(s):  
Glenn M. Chertow ◽  
William F. Owen ◽  
J. Michael Lazarus ◽  
Nancy L. Lew ◽  
Edmund G. Lowrie
Keyword(s):  
Reduction Ratio ◽  
Urea Reduction Ratio

Factors Associated With Urea Reduction Ratio in Acute Renal Failure

2004 ◽  
Vol 28 (12) ◽  
pp. 1076-1081 ◽  
Author(s):  
Orfeas Liangos ◽  
Madhumati Rao ◽  
Robin Ruthazer ◽  
Vaidyanathapuram S. Balakrishnan ◽  
Gopesh Modi ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Reduction Ratio ◽  
Factors Associated ◽  
Urea Reduction Ratio

Urea Reduction Ratio and Urea Kinetic Modeling: A Mathematical Analysis of Changing Dialysis Parameters

1998 ◽  
Vol 18 (6) ◽  
pp. 471-477 ◽  
Author(s):  
Edward Kessler ◽  
Nathan P. Ritchey ◽  
Frank Castro ◽  
Leonard P. Caccamo ◽  
Kimbroe J. Carter ◽  
...  
Keyword(s):  
Kinetic Modeling ◽  
Mathematical Analysis ◽  
Reduction Ratio ◽  
Urea Reduction Ratio

Relationship between urea reduction ratio (URR) and Kt/V in hemodialysis

2002 ◽  
Vol 57 (04) ◽  
pp. 325-326
Author(s):  
G. Virga ◽  
C. Gardin ◽  
S. Mastrosimone ◽  
A. Bonadonna
Keyword(s):  
Reduction Ratio ◽  
Urea Reduction Ratio
Sign in / Sign up

Export Citation Format

Share Document