scholarly journals Advances in Research on Adolescent Suicide and a High Priority Agenda for Future Research

2021 ◽  
Vol 31 (4) ◽  
pp. 1068-1096
Author(s):  
Matthew G. Clayton ◽  
Olivia H. Pollak ◽  
Sarah A. Owens ◽  
Adam Bryant Miller ◽  
Mitchell J. Prinstein
Keyword(s):  
Adolescent Suicide ◽  
Future Research

The Dependency Needs And Perceived Availability And Adequacy Of Relationships In Female Adolescent Suicide Attempters

1995 ◽  
Vol 19 (4) ◽  
pp. 517-531 ◽  
Author(s):  
Brenda J. Bettridge ◽  
Olga Eizner Favreau
Keyword(s):  
Adolescent Suicide ◽  
Suicide Attempts ◽  
Female Adolescent ◽  
Female Adolescents ◽  
Future Research ◽  
Important Goal ◽  
Suicide Attempters ◽  
Perceived Availability ◽  
Female Adolescence ◽  
Adolescent Suicide Attempters

Traditional theories about female adolescent suicide attempters view them as experiencing difficulty in achieving adequate separation-individuation. However, recent work on female adolescence suggests that achieving greater interdependency within relationships rather than increased independence from them is an important goal for nonclinical nonsuicidal female adolescents. We investigated both dependency needs and the perceived availability and adequacy of relationships in 21 female adolescent attempters and 23 nonattempters. Dependency needs did not significantly differentiate suicide attempters from nonattempters. Attempters, however, did report both a smaller social network and fewer intimate relationships than nonattempters, as well as less satisfaction with these relationships. These preliminary results suggest that more research is required to establish whether dependency needs are indeed causally related to the female adolescents' suicide attempts. Future research should also investigate other risk factors such as relational dissatisfaction, familial suicide attempts, and abuse.

scholarly journals Adolescent Suicide as a Failure of Acute Stress-Response Systems

2019 ◽  
Vol 15 (1) ◽  
pp. 425-450 ◽  
Author(s):  
Adam Bryant Miller ◽  
Mitchell J. Prinstein
Keyword(s):  
Risk Factors ◽  
Adolescent Suicide ◽  
Acute Stress ◽  
Future Research ◽  
Biological Responses ◽  
Promising Area ◽  
Response Systems ◽  
Acute Stress Response ◽  
And Behavior ◽  
Suicidal Crisis

Suicide is the second leading cause of death worldwide for adolescents. Despite decades of research on correlates and risk factors for adolescent suicide, we know little about why suicidal ideation and behavior frequently emerge in adolescence and how to predict, and ultimately prevent, suicidal behavior among youths. In this review, we first discuss knowledge regarding correlates, risk factors, and theories of suicide. We then review why adolescence is a period of unique vulnerability, given changing biology and social network reorganization. Next, we present a conceptual model through which to interpret emerging findings in adolescent suicide research. We suggest that a promising area for future research is to examine adolescent suicide as a failure of biological responses to acute stress in the proximal moments of a suicidal crisis. After reviewing initial evidence for this conceptualization, we review future directions for studies on adolescent suicide.

Research Agenda for Youth Suicide Prevention

2017 ◽  
pp. 533-540
Author(s):  
Ann P. Haas ◽  
Herbert Hendin ◽  
Jill Harkavy-Friedman ◽  
Maggie Mortali
Keyword(s):  
At Risk ◽  
Protective Factors ◽  
Suicide Prevention ◽  
Research Agenda ◽  
Adolescent Suicide ◽  
Risk And Protective Factors ◽  
Future Research ◽  
Youth Suicide ◽  
Prevention And Treatment ◽  
Future Reference

The concluding chapter of this section on adolescent suicide lists what we have learned and what we still do not know about identifying and treating youths at risk for suicide and preventing suicide in adolescents. Drawing on data presented in earlier chapters of the section, key findings about youth suicide and risk and protective factors are summarized, along with findings about current approaches to prevention and treatment. An agenda for future research is presented that addresses some of the most significant knowledge gaps about youth suicide and suicide prevention. Methodological difficulties that complicate research in this field are briefly discussed. The chapter concludes with summary conclusions to guide future reference and prevention efforts.

The role of serotonin in adolescent suicide: theoretical, methodological, and clinical concerns

2015 ◽  
Vol 27 (2) ◽  
pp. 129-133 ◽  
Author(s):  
María Dolores Picouto ◽  
Francisco Villar ◽  
María Dolores Braquehais
Keyword(s):  
Suicidal Ideation ◽  
Suicidal Behavior ◽  
Adolescent Suicide ◽  
Suicide Attempts ◽  
Life Stage ◽  
Biological Marker ◽  
Future Research ◽  
Completed Suicide ◽  
Increased Risk

Abstract Introduction: Adolescent suicide is a complex phenomenon that has similarities and differences with adult suicidal behavior. Serotonergic (5-HT) dysfunction has extensively been studied in adults and has been postulated as a biological marker for suicide. Methods: We conducted a comprehensive review of the studies available in MEDLINE from January 1998 until January 2014 on the role of “serotonin” both in adults’ and adolescents’ “completed suicide”, “suicide attempts”, and “suicidal ideation”. Results: Studies on 5-HT conducted in adults and replicated in adolescents have yielded inconsistent results. Although some genes related to the serotonergic system have been associated with an increased risk of suicide, attempts to reproduce those findings have been unsuccessful and a common genetic variant associated to suicidal behavior has yet to be identified. Discussion: Studies on the neurobiology of adolescent suicide should consider the biological specificities of this life stage and of gender differences during this period. Future research designs should also try to integrate findings in the psychological and biological domains. Prospective studies may help understand the process that leads from suicidal ideation to suicide attempts or completed suicides in this population.

Parasite defense mechanisms in bees: behavior, immunity, antimicrobials, and symbionts

2019 ◽  
Vol 4 (1) ◽  
pp. 59-76 ◽  
Author(s):  
Alison E. Fowler ◽  
Rebecca E. Irwin ◽  
Lynn S. Adler
Keyword(s):  
Defense Mechanisms ◽  
Poor Quality ◽  
Future Research ◽  
Immune Priming ◽  
Social Bees ◽  
Bee Health ◽  
Landscape Scales ◽  
And Function ◽  
Solitary Species

Parasites are linked to the decline of some bee populations; thus, understanding defense mechanisms has important implications for bee health. Recent advances have improved our understanding of factors mediating bee health ranging from molecular to landscape scales, but often as disparate literatures. Here, we bring together these fields and summarize our current understanding of bee defense mechanisms including immunity, immunization, and transgenerational immune priming in social and solitary species. Additionally, the characterization of microbial diversity and function in some bee taxa has shed light on the importance of microbes for bee health, but we lack information that links microbial communities to parasite infection in most bee species. Studies are beginning to identify how bee defense mechanisms are affected by stressors such as poor-quality diets and pesticides, but further research on this topic is needed. We discuss how integrating research on host traits, microbial partners, and nutrition, as well as improving our knowledge base on wild and semi-social bees, will help inform future research, conservation efforts, and management.

Dicarbonyl derived post-translational modifications: chemistry bridging biology and aging-related disease

2020 ◽  
Vol 64 (1) ◽  
pp. 97-110
Author(s):  
Christian Sibbersen ◽  
Mogens Johannsen
Keyword(s):  
Mass Spectrometry ◽  
Future Research ◽  
Amino Acid Residues ◽  
Post Translational Modification ◽  
Dicarbonyl Compounds ◽  
Protein Targets ◽  
Post Translational Modifications ◽  
Reactive Protein ◽  
Glycation End Products ◽  
Direct Mass Spectrometry

Abstract In living systems, nucleophilic amino acid residues are prone to non-enzymatic post-translational modification by electrophiles. α-Dicarbonyl compounds are a special type of electrophiles that can react irreversibly with lysine, arginine, and cysteine residues via complex mechanisms to form post-translational modifications known as advanced glycation end-products (AGEs). Glyoxal, methylglyoxal, and 3-deoxyglucosone are the major endogenous dicarbonyls, with methylglyoxal being the most well-studied. There are several routes that lead to the formation of dicarbonyl compounds, most originating from glucose and glucose metabolism, such as the non-enzymatic decomposition of glycolytic intermediates and fructosyl amines. Although dicarbonyls are removed continuously mainly via the glyoxalase system, several conditions lead to an increase in dicarbonyl concentration and thereby AGE formation. AGEs have been implicated in diabetes and aging-related diseases, and for this reason the elucidation of their structure as well as protein targets is of great interest. Though the dicarbonyls and reactive protein side chains are of relatively simple nature, the structures of the adducts as well as their mechanism of formation are not that trivial. Furthermore, detection of sites of modification can be demanding and current best practices rely on either direct mass spectrometry or various methods of enrichment based on antibodies or click chemistry followed by mass spectrometry. Future research into the structure of these adducts and protein targets of dicarbonyl compounds may improve the understanding of how the mechanisms of diabetes and aging-related physiological damage occur.

Effect of Teacher Training Sessions on Listener Perception of Voice Disorders

1985 ◽  
Vol 16 (1) ◽  
pp. 25-28 ◽  
Author(s):  
Nicholas J. DeGregorio ◽  
Nancy Gross Polow
Keyword(s):  
Teacher Training ◽  
School System ◽  
Voice Disorders ◽  
Future Research ◽  
Speech Language Pathologists ◽  
Speech Language Pathologist ◽  
Bergen County ◽  
Experimental Group

The present study was designed to investigate the effect of teacher training sessions on listener perception of voice disorders. Three ASHA certified speech-language pathologists provided the criteria mean. Thirty randomly selected teachers from a Bergen County school system, randomly placed into two groups, served as subjects. The experimental group received three training sessions on consecutive weeks. Three weeks after the end of training, both groups were given a posttest. Listener perception scores were significantly higher for the experimental group. The implications of these results for in-service workshops, teacher/speech-language pathologist interaction and future research are discussed.

Comparative Effects of High-Tech Visual Scene Displays and Low-Tech Isolated Picture Symbols on Engagement From Students With Multiple Disabilities

2019 ◽  
Vol 50 (4) ◽  
pp. 693-702 ◽  
Author(s):  
Christine Holyfield ◽  
Sydney Brooks ◽  
Allison Schluterman
Keyword(s):  
Language Learning ◽  
Augmentative And Alternative Communication ◽  
Visual Analysis ◽  
Multiple Disabilities ◽  
Visual Scene ◽  
Future Research ◽  
High Tech ◽  
Single Subject ◽  
Wide Range ◽  
The Difference

Purpose Augmentative and alternative communication (AAC) is an intervention approach that can promote communication and language in children with multiple disabilities who are beginning communicators. While a wide range of AAC technologies are available, little is known about the comparative effects of specific technology options. Given that engagement can be low for beginning communicators with multiple disabilities, the current study provides initial information about the comparative effects of 2 AAC technology options—high-tech visual scene displays (VSDs) and low-tech isolated picture symbols—on engagement. Method Three elementary-age beginning communicators with multiple disabilities participated. The study used a single-subject, alternating treatment design with each technology serving as a condition. Participants interacted with their school speech-language pathologists using each of the 2 technologies across 5 sessions in a block randomized order. Results According to visual analysis and nonoverlap of all pairs calculations, all 3 participants demonstrated more engagement with the high-tech VSDs than the low-tech isolated picture symbols as measured by their seconds of gaze toward each technology option. Despite the difference in engagement observed, there was no clear difference across the 2 conditions in engagement toward the communication partner or use of the AAC. Conclusions Clinicians can consider measuring engagement when evaluating AAC technology options for children with multiple disabilities and should consider evaluating high-tech VSDs as 1 technology option for them. Future research must explore the extent to which differences in engagement to particular AAC technologies result in differences in communication and language learning over time as might be expected.

Self-Compassion and Quality of Life in Adults Who Stutter

2020 ◽  
Vol 29 (4) ◽  
pp. 2097-2108
Author(s):  
Robyn L. Croft ◽  
Courtney T. Byrd
Keyword(s):  
Quality Of Life ◽  
Social Connectedness ◽  
The Self ◽  
Future Research ◽  
Self Compassion ◽  
Adults Who Stutter ◽  
And Gender ◽  
Relationship Of ◽  
The Impact

Purpose The purpose of this study was to identify levels of self-compassion in adults who do and do not stutter and to determine whether self-compassion predicts the impact of stuttering on quality of life in adults who stutter. Method Participants included 140 adults who do and do not stutter matched for age and gender. All participants completed the Self-Compassion Scale. Adults who stutter also completed the Overall Assessment of the Speaker's Experience of Stuttering. Data were analyzed for self-compassion differences between and within adults who do and do not stutter and to predict self-compassion on quality of life in adults who stutter. Results Adults who do and do not stutter exhibited no significant differences in total self-compassion, regardless of participant gender. A simple linear regression of the total self-compassion score and total Overall Assessment of the Speaker's Experience of Stuttering score showed a significant, negative linear relationship of self-compassion predicting the impact of stuttering on quality of life. Conclusions Data suggest that higher levels of self-kindness, mindfulness, and social connectedness (i.e., self-compassion) are related to reduced negative reactions to stuttering, an increased participation in daily communication situations, and an improved overall quality of life. Future research should replicate current findings and identify moderators of the self-compassion–quality of life relationship.

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