A randomized controlled clinical trial on dose optimization of thalidomide in maintenance treatment for recurrent aphthous stomatitis

2021 ◽  
Author(s):  
Yiwen Deng ◽  
Wei Wei ◽  
Wang Yufeng ◽  
Lei Pan ◽  
Guanhuan Du ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Maintenance Treatment ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Dose Optimization ◽  
Controlled Clinical Trial ◽  
Randomized Controlled Clinical Trial ◽  
Randomized Controlled

New concentration of curcumin orabase in recurrent aphthous stomatitis: A randomized, controlled clinical trial

2020 ◽  
Vol 22 ◽  
pp. 100336
Author(s):  
Seyed Javad Kia ◽  
Arash Mansourian ◽  
Maryam Basirat ◽  
Mohsen Akhavan ◽  
Zahra Mohtasham-Amiri ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Controlled Clinical Trial ◽  
Randomized Controlled Clinical Trial ◽  
Randomized Controlled

Comparision of two fluoride varnishes for controlling white spot lesions. Randomized clinical trial

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Jesús Alberto Luengo - Fereira
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
White Spot ◽  
Controlled Clinical Trial ◽  
White Spot Lesions ◽  
Randomized Controlled Clinical Trial ◽  
Chi Square ◽  
Randomized Controlled ◽  
Anterior Teeth ◽  
The Mean

Objective: To compare two fluorinated varnishes for the control of white spot lesions.Material and Methods: A randomized controlled clinical trial was conducted. A total of 103 active whitespot lesions on permanent upper anterior teeth from 24 patients, aged 7 to 9 years were randomly assigned totwo groups, G1: Duraphat® (n=52) and G2: DuraShield® (n=51). Weekly applications were perform for fourconsecutive weeks. Fifth week the dimension, regression and activity of the lesions were evaluated. Student’sT test, Wilcoxon Ranks and Chi square were used at 5% significance. Results: At the end of the study, the lesion reduction was observed in 69.7%, finding significant differences(p<0.05) in the mean of the initial and final dimensions in general (2.74 mm to 1.91 mm) and in each group, G1(2.84 mm to 2.03 mm), G2 (2.64 mm to 1.78 mm). In the activity of the lesions, it was found in the G1, 12 active and6 inactive lesions; while in G2, there were 14 active and 29 inactive; these differences were significant (p<0.05). Conclusions: The two evaluated products showed similar clinical efficacy in the remineralization of activewhite spot lesions after 4 weeks of therapy.

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