Hedgehog signaling promotes multidrug resistance by regulation of ABC transporters in oral squamous cell carcinoma

2020 ◽  
Vol 49 (9) ◽  
pp. 897-906
Author(s):  
Xiangwan Lu ◽  
Zhanghao Wang ◽  
Hongxing Huang ◽  
Hua Wang
Keyword(s):  
Squamous Cell Carcinoma ◽  
Multidrug Resistance ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Abc Transporters ◽  
Hedgehog Signaling

Expression of hedgehog signaling molecules as a prognostic indicator of oral squamous cell carcinoma

Head & Neck ◽  
2012 ◽  
Vol 34 (11) ◽  
pp. 1556-1561 ◽  
Author(s):  
Yi-Fen Wang ◽  
Chun-Ju Chang ◽  
Chin-Ping Lin ◽  
Shyue-Yih Chang ◽  
Pen-Yuan Chu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Hedgehog Signaling ◽  
Prognostic Indicator ◽  
Signaling Molecules

scholarly journals Sonic hedgehog signaling promotes growth of oral squamous cell carcinoma cells associated with bone destruction

Oral Oncology ◽  
2012 ◽  
Vol 48 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Tatsuki Honami ◽  
Tsuyoshi Shimo ◽  
Tatsuo Okui ◽  
Naito Kurio ◽  
Nur Mohammad Monsur Hassan ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Sonic Hedgehog ◽  
Squamous Cell ◽  
Hedgehog Signaling ◽  
Bone Destruction ◽  
Carcinoma Cells ◽  
Sonic Hedgehog Signaling

Multidrug resistance in oral squamous cell carcinoma: The role of vacuolar ATPases

2010 ◽  
Vol 295 (2) ◽  
pp. 135-143 ◽  
Author(s):  
Mario Pérez-Sayáns ◽  
José Manuel Somoza-Martín ◽  
Francisco Barros-Angueira ◽  
Pilar Gayoso Diz ◽  
José Manuel Gándara Rey ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Multidrug Resistance ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Vacuolar Atpases

Role of Clinical Palpation in Evaluation of Cervical Lymph Node in Oral Squamous Cell Carcinoma

2013 ◽  
Vol 1 (2) ◽  
pp. 02-06
Author(s):  
SM Anwar Sadat ◽  
Sufia Nasrin Rita ◽  
Shoma Banik ◽  
Md Nazmul Hasan Khandker ◽  
Md Mahfuz Hossain ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Oral Squamous Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Predictive Value ◽  
Cervical Lymph Node ◽  
Betel Quid ◽  
Cervical Lymph Nodes

A cross sectional study of 29 cases of oral squamous cell carcinoma with or without  cervical lymph node metastasis was done among Bangladeshi patients from January 2006 to December 2007. Majority of the study subjects (34.5%) belonged to the age group of 40-49 years. 58.6% of the study subjects were male, while remaining 41.4% of them were female. 51.7% of the lesions were located in the alveolar ridge where the other common sites were buccal mucosa (27.6%) and retro molar area (13.8%). Half of the study subjects (51.7%) were habituated to betel quid chewing followed by 37.9% and 10.3% were habituated to smoking and betel quid-smoking respectively. Grade I lesions was most prevalent (75.9%) in the study subjects.  Majority of cases presented with Stage IV lesions (55.2%). The sensitivity, specificity, positive predictive value, negative predictive value & accuracy of clinical palpation method for determining metastatic cervical lymph nodes were 93.33%, 64.29%, 73.68%, 90% and 79.3% respectively. Careful and repeated clinical palpation plays important role in evaluation of cervical lymph nodes though several modern techniques may help additionally in the management of oral cancer.DOI: http://dx.doi.org/10.3329/updcj.v1i2.13978 Update Dent. Coll. j. 2011: 1(2): 02-06

Management of Neck in Oral Squamous Cell Carcinoma

2011 ◽  
Vol 3 (6) ◽  
pp. 419-422
Author(s):  
Dr. Shool Rohit S Dr. Shool Rohit S ◽  
◽  
Dr. Anand P Zingade ◽  
Dr. Manish Kumar
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell
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