scholarly journals Prognostic value of the immunohistochemical detection of cancer-associated fibroblasts in oral cancer: A systematic review and meta-analysis

2017 ◽  
Vol 47 (5) ◽  
pp. 443-453 ◽  
Author(s):  
Mauricio Rocha Dourado ◽  
Eliete N. S. Guerra ◽  
Tuula Salo ◽  
Daniel W. Lambert ◽  
Ricardo D. Coletta
Keyword(s):  
Systematic Review ◽  
Oral Cancer ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Cancer Associated Fibroblasts ◽  
Immunohistochemical Detection

Oral cancer‐associated fibroblasts predict poor survival: Systematic review and meta‐analysis

Oral Diseases ◽  
2019 ◽  
Vol 26 (4) ◽  
pp. 733-744 ◽  
Author(s):  
Diana Graizel ◽  
Ayelet Zlotogorski‐Hurvitz ◽  
Igor Tsesis ◽  
Eyal Rosen ◽  
Ron Kedem ◽  
...  
Keyword(s):  
Systematic Review ◽  
Oral Cancer ◽  
Meta Analysis ◽  
Cancer Associated Fibroblasts ◽  
Poor Survival

scholarly journals Prognostic value of Neutrophil‐to‐lymphocyte ratio in COVID‐19 patients: A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Juan R. Ulloque‐Badaracco ◽  
W. Ivan Salas‐Tello ◽  
Ali Al‐kassab‐Córdova ◽  
Esteban A. Alarcón‐Braga ◽  
Vicente A. Benites‐Zapata ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio

scholarly journals Tumor-Infiltrating Lymphocytes in the Tumor Microenvironment of Laryngeal Squamous Cell Carcinoma: Systematic Review and Meta-Analysis

Biomedicines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 486
Author(s):  
Juan P. Rodrigo ◽  
Mario Sánchez-Canteli ◽  
Fernando López ◽  
Gregory T. Wolf ◽  
Juan C. Hernández-Prera ◽  
...  
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Tumor Microenvironment ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Prognostic Value ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Meta Analysis ◽  
Tumor Infiltrating Lymphocytes ◽  
Infiltrating Lymphocytes

The presence of tumor-infiltrating lymphocytes (TIL) in the tumor microenvironment has been demonstrated to be of prognostic value in various cancers. In this systematic review and meta-analysis, we investigated the prognostic value of TIL in laryngeal squamous cell carcinoma (LSCC). We performed a systematic search in PubMed for publications that investigated the prognostic value of TIL in LSCC. A meta-analysis was performed including all studies assessing the association between TIL counts in hematoxylin-eosin (HE)-stained sections, for CD8+ and/or CD3+/CD4+ TIL and overall survival (OS) or disease-free survival (DFS). The pooled meta-analysis showed a favorable prognostic role for stromal TIL in HE sections for OS (HR 0.57, 95% CI 0.36–0.91, p = 0.02), and for DFS (HR 0.56, 95% CI 0.34–0.94, p = 0.03). High CD8+ TIL were associated with a prolonged OS (HR 0.62, 95% CI 0.4–0.97, p = 0.04) and DFS (HR 0.73, 95% CI 0.34–0.94, p = 0.002). High CD3+/CD4+ TIL demonstrated improved OS (HR 0.32, 95% CI 0.16–0.9, p = 0.03) and DFS (HR 0.23, 95% CI 0.10–0.53, p = 0.0005). This meta-analysis confirmed the favorable prognostic significance of TIL in LSCC. High stromal TIL evaluated in HE sections and intra-tumoral and stromal CD3+, CD4+ and/or CD8+ TIL might predict a better clinical outcome.

Efficacy of hypermethylated DNA biomarkers in saliva and oral swabs for oral cancer diagnosis: Systematic review and meta‐analysis

Oral Diseases ◽  
2021 ◽  
Author(s):  
John Adeoye ◽  
Azeez Arisekola Alade ◽  
Wang‐yong Zhu ◽  
Weilan Wang ◽  
Siu‐Wai Choi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Oral Cancer ◽  
Cancer Diagnosis ◽  
Meta Analysis
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