E-cadherin-mediated impairment increases anti-apoptotic mechanism through upregulation of Bcl-2: An immunohistochemical study in various patterns of invasion of oral squamous cell carcinoma

2017 ◽  
Author(s):  
Nikita Gulati ◽  
Devi Charan Shetty ◽  
Ajit Singh Rathore ◽  
Saurabh Juneja ◽  
Anshi Jain
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Immunohistochemical Study ◽  
Apoptotic Mechanism ◽  
E Cadherin

scholarly journals Role of E-cadherin in Progression of Oral Squamous Cell Carcinoma: A Retrospective Immunohistochemical Study

2018 ◽  
Vol 19 (9) ◽  
pp. 1105-1110 ◽  
Author(s):  
Seema Sharma ◽  
Awadhesh Gupta ◽  
Mohammed Abidullah ◽  
Swathi Bhuvinder ◽  
Padmavathi Katragadda
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Immunohistochemical Study ◽  
E Cadherin

p-Akt and its relationship with clinicopathological features and survival in oral squamous cell carcinoma: an immunohistochemical study

2014 ◽  
Vol 44 (7) ◽  
pp. 532-537 ◽  
Author(s):  
Hélder Antônio Rebelo Pontes ◽  
Flávia Sirotheau Corrêa Pontes ◽  
Adriana Souza de Jesus ◽  
Maiza Cristina Pereira Soares ◽  
Fábio Luiz Neves Gonçalves ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Immunohistochemical Study ◽  
Clinicopathological Features

scholarly journals Expression of Extracellular Matrix—Laminin in Oral Squamous Cell Carcinoma: An Immunohistochemical Study

2012 ◽  
Vol 13 (2) ◽  
pp. 194-200
Author(s):  
Sonam C Kapse ◽  
Ajit V Koshy ◽  
Nirmala N Rao ◽  
Sushant S Kamat ◽  
Kamal Kiswani ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Immunohistochemical Study ◽  
Tumor Development ◽  
Treatment Strategies ◽  
Prognostic Indicators ◽  
Chi Square

ABSTRACT Aim To evaluate the expression of laminin in various grades of oral squamous cell carcinoma (OSCC) in order to determine whether this protein can be used as a marker for early detection and elucidation of oral cancer. Materials and methods Immunohistochemical staining for laminin was done on 60 selected archival blocks of histopathologically diagnosed cases of primary OSCC and the laminin expression was compared between the different histopathological grades of primary OSCC. The statistical analysis was performed by using Chi-square (÷ square) test and Gaussiantest with a probability of p < 0.05 was considered as significant. Results It was observed that laminin expression decreased with tumor progression which may be correlated to the tumor aggressiveness. Conclusion There was a gradual decrease of laminin staining with decreasing cellular differentiation, with differentiated lesions showing a more conspicuous staining of basement membrane glycoprotein than less differentiated lesions. Clinical significance An understanding of how the extracellular matrix influences tumor development and invasion is fundamental in the development of new prognostic indicators and treatment strategies for oral squamous cell carcinoma. How to cite this article Koshy AV, Rao NN, Kamat SS, Kiswani K, Kapse SC, Shaikh NA. Expression of Extracellular Matrix— Laminin in Oral Squamous Cell Carcinoma: An Immunohistochemical Study. J Contemp Dent Pract 2012;13(2):194-200.

scholarly journals EKSPRESI p53 DAN E-CADHERIN SEBAGAI PREDIKTOR PROGNOSIS PADA KARSINOMA SEL SKUAMOSA RONGGA MULUT DI RSUP DR. KARIADI SEMARANG

2019 ◽  
Vol 5 (1) ◽  
pp. 7-17
Author(s):  
Clara Pangaribuan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
E Cadherin

p53 AND E-CADHERIN EXPRESSION AS  PREDICTORS OF PROGNOSTIC IN ORAL SQUAMOUS CELL CARCINOMA AT KARIADI HOSPITAL SEMARANG

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