Glioblastoma versus solitary brain metastasis: MRI differentiation using the edema perfusion gradient

2021 ◽  
Author(s):  
Fernando Aparici‐Robles ◽  
Andjoli Davidhi ◽  
José Miguel Carot‐Sierra ◽  
Alexandre Perez‐Girbes ◽  
Joan Carreres‐Polo ◽  
...  
Keyword(s):  
Brain Metastasis ◽  
Solitary Brain Metastasis

ENDOMETRIAL CANCER WITH A SOLITARY BRAIN METASTASIS. A CLINICAL CASE STUDY

2018 ◽  
pp. 37-42
Author(s):  
Nadezhda Vagarshakovna Sevyan ◽  
Vladislav Borisovich Karakhan ◽  
Ali Khasyanovich Bekyashev ◽  
David Romanovich Naskhletashvili ◽  
Nikolai Alexandrovich Kozlov ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Brain Metastasis ◽  
Clinical Case ◽  
Solitary Brain Metastasis ◽  
Clinical Case Study

Outcome after surgery in supratentorial and infratentorial solitary brain metastasis

2019 ◽  
Vol 161 (5) ◽  
pp. 1047-1053
Author(s):  
Rik Demaerel ◽  
Johannes van Loon ◽  
Frank Van Calenbergh
Keyword(s):  
Brain Metastasis ◽  
Solitary Brain Metastasis

Cardiac angiosarcoma presenting as a solitary brain metastasis

2020 ◽  
Vol 8 (6) ◽  
pp. 426-427
Author(s):  
Alexander J. Baumgartner ◽  
Jared T. Ahrendsen ◽  
Hemant Varma ◽  
Ashley Ward ◽  
Samuel Frank
Keyword(s):  
Brain Metastasis ◽  
Solitary Brain Metastasis ◽  
Cardiac Angiosarcoma

scholarly journals Intraoperative radiotherapy to treat newly diagnosed solitary brain metastasis: initial experience and long-term outcomes

2015 ◽  
Vol 122 (4) ◽  
pp. 825-832 ◽  
Author(s):  
Robert J. Weil ◽  
Gaurav G. Mavinkurve ◽  
Samuel T. Chao ◽  
Michael A. Vogelbaum ◽  
John H. Suh ◽  
...  
Keyword(s):  
Brain Metastasis ◽  
Intraoperative Radiotherapy ◽  
Progression Free Survival ◽  
Patient Treatment ◽  
Karnofsky Performance Scale ◽  
Newly Diagnosed ◽  
Term Survival ◽  
Solitary Brain Metastasis ◽  
Free Survival

OBJECT The authors assessed the feasibility of intraoperative radiotherapy (IORT) using a portable radiation source to treat newly diagnosed, surgically resected, solitary brain metastasis (BrM). METHODS In a nonrandomized prospective study, 23 patients with histologically confirmed BrM were treated with an Intrabeam device that delivered 14 Gy to a 2-mm depth to the resection cavity during surgery. RESULTS In a 5-year minimum follow-up period, progression-free survival from the time of surgery with simultaneous IORT averaged (± SD) 22 ± 33 months (range 1–96 months), with survival from the time of BrM treatment with surgery+IORT of 30 ± 32 months (range 1–96 months) and overall survival from the time of first cancer diagnosis of 71 ± 64 months (range 4–197 months). For the Graded Prognostic Assessment (GPA), patients with a score of 1.5–2.0 (n = 12) had an average posttreatment survival of 21 ± 26 months (range 1–96 months), those with a score of 2.5–3.0 (n = 7) had an average posttreatment survival of 52 ± 40 months (range 5–94 months), and those with a score of 3.5–4.0 (n = 4) had an average posttreatment survival of 17 ± 12 months (range 4–28 months). A BrM at the treatment site recurred in 7 patients 9 ± 6 months posttreatment, and 5 patients had new but distant BrM 17 ± 3 months after surgery+IORT. Six patients later received whole-brain radiation therapy, 7 patients received radiosurgery, and 2 patients received both treatments. The median Karnofsky Performance Scale scores before and 1 and 3 months after surgery were 80, 90, and 90, respectively; at the time of this writing, 3 patients remain alive with a CNS progression-free survival of > 90 months without additional BrM treatment. CONCLUSIONS The results of this study demonstrate the feasibility of resection combined with IORT at a dose of 14 Gy to a 2-mm peripheral margin to treat a solitary BrM. Local control, distant control, and long-term survival were comparable to those of other commonly used modalities. Surgery combined with IORT seems to be a potential adjunct to patient treatment for CNS involvement by systemic cancer.

Lung cancer with synchronous solitary brain metastasis: palliative or radical treatment?

2004 ◽  
Vol 6 (7) ◽  
pp. 397-402 ◽  
Author(s):  
Pino Alcántara ◽  
Andrea Bezjak ◽  
Laura Cerezo Padellano
Keyword(s):  
Lung Cancer ◽  
Brain Metastasis ◽  
Solitary Brain Metastasis ◽  
Radical Treatment
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