COVID‐19 hospitalization is associated with pulmonary / diffusion abnormalities but not post‐acute sequelae of COVID‐19 severity

Author(s):  
Grace Y. Lam ◽  
A. Dean Befus ◽  
Ronald W. Damant ◽  
Giovanni Ferrara ◽  
Desi P. Fuhr ◽  
...  
Keyword(s):  
1962 ◽  
Vol 17 (6) ◽  
pp. 885-892 ◽  
Author(s):  
Albert H. Niden ◽  
Charles Mittman ◽  
Benjamin Burrows

Methods have been presented for assessing pulmonary diffusion by the “equilibration technique” in the experimental intact dog and perfused lung while controlling ventilation with a whole body respirator. No significant change in diffusion of carbon monoxide was noted between open and closed chest anesthetized animals, with duration of anesthesia in the intact dog, or with duration of perfusion of the isolated dog's lung. There was no demonstrable difference in diffusion when arterialized blood was used as the perfusate in place of mixed venous blood in the lung perfusions suggesting that within the range studied the Po2, Pco2, and pH of pulmonary artery blood does not directly affect the diffusion of carbon monoxide. Retrograde perfusions of dogs' lungs did not significantly alter diffusion, suggesting that pulmonary venous resistance was not significantly lower than pulmonary arterial resistance in the perfused dog lung at the flows and pressures studied. The equilibration technique for measuring pulmonary diffusion and assessing the uniformity of diffusion was well suited to the study of pulmonary diffusing characteristics in the experimental animal. Submitted on January 8, 1962


1973 ◽  
Vol 18 (3) ◽  
pp. 285-308 ◽  
Author(s):  
Ewald R. Weibel ◽  
Peter Untersee ◽  
Joan Gil ◽  
Martin Zulauf

CHEST Journal ◽  
1993 ◽  
Vol 104 (4) ◽  
pp. 1085-1089 ◽  
Author(s):  
James J. Egan ◽  
Sanja Kalra ◽  
Nizar Yonan ◽  
Philip S. Hasleton ◽  
Nicholas Brooks ◽  
...  

1986 ◽  
Vol 4 (3) ◽  
pp. 185-188 ◽  
Author(s):  
B. S. Rasmussen ◽  
B. Hanel ◽  
K. Jensen ◽  
B. Serup ◽  
N.H. Secher

1964 ◽  
Vol 19 (3) ◽  
pp. 465-468 ◽  
Author(s):  
Richard A. Krumholz ◽  
Joseph C. Ross

Pulmonary diffusing capacity increases with exercise. The rapidity of this increase after the onset of exercise and factors which may alter it, i.e. atropine (2.0 mg i.v.) and reserpine (0.5 mg/day p.o. for 7 days), were investigated. Breath-holding Dl determinations were made before exercise began, at 0–10 sec of exercise, after 1, 2, and 3 min of exercise, and 3 min after the end of exercise. Dl was already strikingly increased at 0–10 sec of exercise, although further increases occurred during the 3-min exercise period. Following atropine administration in nine subjects the immediate rise in Dl at 0–10 sec of exercise was significantly reduced (P < 0.01), but the increases with further exercise were not significantly altered. After the reserpine administration in six subjects, the 0–10 sec exercise Dl values tended to be lower, but not to a significance level of <.05, and there was a tendency toward lower Dl values throughout the 3-min exercise period. This study suggests, then, that the immediate and the later increases in Dl with exercise are produced by two different mechanisms. pulmonary diffusion; pulmonary diffusion in exercise; mechanism for increased diffusion in exercise; pulmonary capillary bed Submitted on September 23, 1963


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