scholarly journals What proportion of patients with chronic noncancer pain are prescribed an opioid medicine? Systematic review and meta‐regression of observational studies

2020 ◽  
Vol 287 (5) ◽  
pp. 458-474 ◽  
Author(s):  
S. Mathieson ◽  
G. Wertheimer ◽  
C.G. Maher ◽  
C.‐W. Christine Lin ◽  
A.J. McLachlan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Observational Studies ◽  
Chronic Noncancer Pain ◽  
Meta Regression ◽  
Noncancer Pain

The Prevalence of Opioid Analgesic Use in People with Chronic Noncancer Pain: Systematic Review and Meta-Analysis of Observational Studies

Pain Medicine ◽  
2020 ◽  
Author(s):  
Graeme Wertheimer ◽  
Stephanie Mathieson ◽  
Christopher G Maher ◽  
Chung-Wei Christine Lin ◽  
Andrew J McLachlan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Observational Studies ◽  
Opioid Analgesic ◽  
Risk Of Bias ◽  
Opioid Use ◽  
Chronic Noncancer Pain ◽  
Moderate Quality ◽  
Meta Regression ◽  
Noncancer Pain ◽  
Quality Evidence

Abstract Objective To review studies examining the proportion of people with chronic noncancer pain who report consuming opioids and characteristics associated with their use. Design Systematic review. Methods We searched databases from inception to February 8, 2020, and conducted citation tracking. We included observational studies reporting the proportion of adults with chronic noncancer pain who used opioid analgesics. Opioids were categorized as weak (e.g., codeine) or strong (e.g., oxycodone). Study risk of bias was assessed, and Grading of Recommendations Assessment, Development and Evaluations provided a summary of the overall quality. Results were pooled using a random-effects model. Meta-regression determined factors associated with opioid use. Results Sixty studies (N=3,961,739) reported data on opioid use in people with chronic noncancer pain from 1990 to 2017. Of these 46, 77% had moderate risk of bias. Opioid use was reported by 26.8% (95% confidence interval [CI], 23.1–30.8; moderate-quality evidence) of people with chronic noncancer pain. The use of weak opioids (17.3%; 95% CI 11.9–24.4; moderate-quality evidence) was more common than the use of strong opioids (9.8%; 95% CI, 6.8–14.0; low-quality evidence). Meta-regression determined that opioid use was associated with geographic region (P=0.02; lower in Europe than North America), but not sampling year (P=0.77), setting (P=0.06), diagnosis (P=0.34), or disclosure of funding (P=0.77). Conclusions Our review summarized data from over 3.9 million people with chronic noncancer pain reporting their opioid use. Between 1990 and 2017, one-quarter of people with chronic noncancer pain reported taking opioids, and this proportion did not change over time.

Are Physicians Safely Prescribing Opioids for Chronic Noncancer Pain? A Systematic Review of Current Evidence

Pain Practice ◽  
2015 ◽  
Vol 16 (3) ◽  
pp. 370-383 ◽  
Author(s):  
Juliana Tournebize ◽  
Valérie Gibaja ◽  
Amandine Muszczak ◽  
Jean-Pierre Kahn
Keyword(s):  
Systematic Review ◽  
Current Evidence ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

scholarly journals Outcomes Associated with Opioid Use in the Treatment of Chronic Noncancer Pain in Older Adults: A Systematic Review and Meta-Analysis

2010 ◽  
Vol 58 (7) ◽  
pp. 1353-1369 ◽  
Author(s):  
Maria Papaleontiou ◽  
Charles R. Henderson Jr ◽  
Barbara J. Turner ◽  
Alison A. Moore ◽  
Yelena Olkhovskaya ◽  
...  
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Meta Analysis ◽  
Opioid Use ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

Factors that Influence Coping with Chronic Noncancer Pain in European Countries: A Systematic Review of Measuring Instruments

2020 ◽  
Vol 21 (2) ◽  
pp. 123-133 ◽  
Author(s):  
Rocío Cáceres-Matos ◽  
Eugenia Gil-García ◽  
Andrés Cabrera-León ◽  
Ana María Porcel-Gálvez ◽  
Sergio Barrientos-Trigo
Keyword(s):  
Systematic Review ◽  
European Countries ◽  
Measuring Instruments ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain
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