Incidence of new-onset autoimmune disease in girls and women with pre-existing autoimmune disease after quadrivalent human papillomavirus vaccination: a cohort study

2016 ◽  
Vol 280 (6) ◽  
pp. 618-626 ◽  
Author(s):  
O. Grönlund ◽  
E. Herweijer ◽  
K. Sundström ◽  
L. Arnheim-Dahlström
Keyword(s):  
Cohort Study ◽  
Human Papillomavirus ◽  
Autoimmune Disease ◽  
Human Papillomavirus Vaccination ◽  
New Onset

scholarly journals Risk of new onset autoimmune disease in 9- to 25-year-old women exposed to human papillomavirus-16/18 AS04-adjuvanted vaccine in the United Kingdom

2016 ◽  
Vol 12 (11) ◽  
pp. 2862-2871 ◽  
Author(s):  
Corinne Willame ◽  
Dominique Rosillon ◽  
Julia Zima ◽  
Maria-Genalin Angelo ◽  
Anke L. Stuurman ◽  
...  
Keyword(s):  
United Kingdom ◽  
Human Papillomavirus ◽  
Autoimmune Disease ◽  
Human Papillomavirus 16 ◽  
Adjuvanted Vaccine ◽  
The United Kingdom ◽  
New Onset

scholarly journals Human Papillomavirus Vaccination and Infection in Young Sexual Minority Men: The P18 Cohort Study

2019 ◽  
Vol 33 (4) ◽  
pp. 149-156 ◽  
Author(s):  
Perry N. Halkitis ◽  
Pamela Valera ◽  
Caleb E. LoSchiavo ◽  
Stephen E. Goldstone ◽  
Maria Kanztanou ◽  
...  
Keyword(s):  
Cohort Study ◽  
Human Papillomavirus ◽  
Sexual Minority ◽  
Human Papillomavirus Vaccination ◽  
Sexual Minority Men ◽  
Minority Men

scholarly journals Impact of a human papillomavirus vaccination programme within organized cervical cancer screening: cohort study.

2022 ◽  
pp. cebp.0895.2021
Author(s):  
Cecilia Acuti Martellucci ◽  
Margherita Morettini ◽  
Julia ML Brotherton ◽  
Karen Canfell ◽  
Lamberto Manzoli ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cohort Study ◽  
Human Papillomavirus ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Vaccination Programme ◽  
Human Papillomavirus Vaccination

scholarly journals Human papillomavirus vaccination and all-cause morbidity in adolescent girls: a cohort study of absence from school due to illness

2021 ◽  
Author(s):  
Anders Hviid ◽  
Nicklas M Thorsen ◽  
Louise N Thomsen ◽  
Frederik T Møller ◽  
Andreas Wiwe ◽  
...  
Keyword(s):  
Cohort Study ◽  
Public Schools ◽  
Human Papillomavirus ◽  
Random Effects ◽  
Hpv Vaccination ◽  
Vaccine Safety ◽  
Human Papillomavirus Vaccination ◽  
Medical Diagnoses ◽  
The Individual ◽  
Rate Ratios

Abstract Background A growing body of evidence supports the safety of the human papillomavirus (HPV) vaccines. However, concerns about autonomic dysfunction syndromes and non-specific symptoms continue to linger. These conditions are not easily captured by traditional diagnostic classification schemes and call for innovative approaches to the study of vaccine safety which take more general measures of all-cause morbidity into account. Methods Taking advantage of the unique Danish registers, including regional registration of absence from school, we conducted a cohort study of 14 068 adolescent Danish girls attending 5th through 9th grade in public schools in the municipality of Copenhagen during 1 August 2013–23 January 2018. We obtained time-varying HPV vaccination status and demographic information from nationwide registers. Using Poisson regression with random effects, we estimated rate ratios (RRs) of absence due to illness, comparing HPV-vaccinated girls with unvaccinated girls with adjustment for grade, season, calendar period, demographic factors and random effects at the individual, class and school levels. Results Our study included 6 206 188 school days with 213 221 days of absence from school due to illness (absence rate, 3.4%). Comparing absence rates due to illness in HPV-vaccinated and unvaccinated girls yielded an adjusted RR of 1.00 (95% confidence interval [CI], 0.98–1.03). Conclusions Our study provides an important and novel contribution to HPV vaccine safety. Using absence from school records, we were able to address important safety concerns without relying on medical diagnoses. We conclude that HPV vaccination does not increase the risk of morbidity in any manner that manifests as absence from school due to illness.

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