Polymorphism in CYP2D6 and CYP2C19, members of the cytochrome P450 mixed-function oxidase system, in the metabolism of psychotropic drugs

J. Stingl; R. Viviani

doi:10.1111/joim.12317

Polymorphism in CYP2D6 and CYP2C19, members of the cytochrome P450 mixed-function oxidase system, in the metabolism of psychotropic drugs

Journal of Internal Medicine ◽

10.1111/joim.12317 ◽

2015 ◽

Vol 277 (2) ◽

pp. 167-177 ◽

Cited By ~ 36

Author(s):

J. Stingl ◽

R. Viviani

Keyword(s):

Cytochrome P450 ◽

Psychotropic Drugs ◽

Mixed Function Oxidase ◽

Oxidase System ◽

Mixed Function Oxidase System

Download Full-text

Reconstitution of the Brain Mixed Function Oxidase System: Purification of NADPH-Cytochrome P450 Reductase and Partial Purification of Cytochrome P450 from Whole Rat Brain

Journal of Neurochemistry ◽

10.1111/j.1471-4159.1992.tb09408.x ◽

1992 ◽

Vol 59 (2) ◽

pp. 575-581 ◽

Cited By ~ 24

Author(s):

Arthur F. Bergh ◽

Henry W. Strobel

Keyword(s):

Cytochrome P450 ◽

Rat Brain ◽

Partial Purification ◽

Mixed Function Oxidase ◽

Cytochrome P450 Reductase ◽

Oxidase System ◽

Nadph Cytochrome ◽

Mixed Function Oxidase System ◽

Nadph Cytochrome P450 Reductase ◽

The Brain

Download Full-text

Characterization of cytochrome P450 dependent mixed-function oxidase system of gilthead seabream (sparus aurata; sparidae) liver

Comparative Biochemistry and Physiology Part B Comparative Biochemistry ◽

10.1016/0305-0491(93)90349-a ◽

1993 ◽

Vol 104 (1) ◽

pp. 133-139 ◽

Cited By ~ 4

Author(s):

Emel Arinç ◽

Alaattin şen

Keyword(s):

Cytochrome P450 ◽

Sparus Aurata ◽

Gilthead Seabream ◽

Mixed Function Oxidase ◽

Oxidase System ◽

Mixed Function Oxidase System

Download Full-text

The metabolism of leukotrienes, detoxification of reactive oxygen species and the activity of the cytochrome P450 mixed function oxidase system in sensitised guinea-pig lungs

Pulmonary Pharmacology ◽

10.1016/0952-0600(91)90007-p ◽

1991 ◽

Vol 4 (3) ◽

pp. 165-169 ◽

Cited By ~ 2

Author(s):

M.H. Grant ◽

I.W. Rodger

Keyword(s):

Reactive Oxygen Species ◽

Cytochrome P450 ◽

Guinea Pig ◽

Reactive Oxygen ◽

Oxygen Species ◽

Mixed Function Oxidase ◽

Oxidase System ◽

Mixed Function Oxidase System

Download Full-text

Acidic steroid metabolites: Biosynthesis of steroid carboxylic acids by rabbit liver microsomes and the involvement of a cytochrome P450-independent mixed function oxidase system

Journal of Steroid Biochemistry ◽

10.1016/0022-4731(78)90039-0 ◽

1978 ◽

Vol 9 (11) ◽

pp. 1099-1104 ◽

Cited By ~ 7

Author(s):

Arun C. Dey ◽

Ian R. Senciall

Keyword(s):

Cytochrome P450 ◽

Carboxylic Acids ◽

Liver Microsomes ◽

Rabbit Liver ◽

Mixed Function Oxidase ◽

Oxidase System ◽

Acidic Steroid ◽

Mixed Function Oxidase System

Download Full-text

Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome P-450 oxidoreductase and epoxide hydratase genes.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)89763-0 ◽

1985 ◽

Vol 260 (1) ◽

pp. 515-521 ◽

Cited By ~ 2

Author(s):

D L Simmons ◽

P A Lalley ◽

C B Kasper

Keyword(s):

Gene Families ◽

Mixed Function Oxidase ◽

Oxidase System ◽

Nadph Cytochrome ◽

Genetic Localization ◽

Epoxide Hydratase ◽

Mixed Function Oxidase System ◽

Cytochrome P 450

Download Full-text

Induction of the hepatic mixed-function oxidase system by synthetic glucocorticoids. Transcriptional and post-transcriptional regulation.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)75930-4 ◽

1987 ◽

Vol 262 (1) ◽

pp. 326-332

Author(s):

D L Simmons ◽

P McQuiddy ◽

C B Kasper

Keyword(s):

Transcriptional Regulation ◽

Mixed Function Oxidase ◽

Oxidase System ◽

Mixed Function Oxidase System ◽

Post Transcriptional Regulation ◽

Synthetic Glucocorticoids

Download Full-text

Effects of some toxic metals on hepatic microsomal mixed function oxidase system of the rat

Acta Academiae Medicinae Wuhan ◽

10.1007/bf02856869 ◽

1984 ◽

Vol 4 (3) ◽

pp. 158-162 ◽

Cited By ~ 1

Author(s):

Xiao Gong-hua ◽

Song Rui-kun ◽

Liu Yu-gu

Keyword(s):

Toxic Metals ◽

Mixed Function Oxidase ◽

Oxidase System ◽

Mixed Function Oxidase System ◽

Microsomal Mixed Function Oxidase

Download Full-text

Kinetic and substrate binding characterization of hepatic mixed function oxidase system in monkeys with primaquine and (N1-3-acetyl-4-5-dihydro-2-furanyl)-N4-(methoxy-8-quinolinyl) 1,4-peptane-diamine

Biochemical Pharmacology ◽

10.1016/0006-2952(92)90261-g ◽

1992 ◽

Vol 43 (4) ◽

pp. 904-907 ◽

Cited By ~ 3

Author(s):

Pratima Srivastava ◽

Sanjeev K. Sahni ◽

Laut M. Tripathi ◽

Sunil K. Puri ◽

Guru P. Dutta ◽

...

Keyword(s):

Substrate Binding ◽

Mixed Function Oxidase ◽

Oxidase System ◽

Mixed Function Oxidase System

Download Full-text

Glutathione Depletion by Phorone Organ Specificity and Effect on Hepatic Microsomal Mixed-Function Oxidase System

Drug and Chemical Toxicology ◽

10.3109/01480548609042831 ◽

1986 ◽

Vol 9 (1) ◽

pp. 67-73 ◽

Cited By ~ 20

Author(s):

Maged Younes ◽

Satish C. Sharma ◽

C. P. Siegers

Keyword(s):

Glutathione Depletion ◽

Organ Specificity ◽

Mixed Function Oxidase ◽

Oxidase System ◽

Mixed Function Oxidase System ◽

Microsomal Mixed Function Oxidase

Download Full-text

Effects of excess and deficiency of dietary methionine on mixed-function oxidase system of hepatic microsomes in male broilers

Comparative Biochemistry and Physiology Part A Physiology ◽

10.1016/0300-9629(91)90336-b ◽

1991 ◽

Vol 100 (4) ◽

pp. 1049-1052 ◽

Cited By ~ 2

Author(s):

Kazuaki Takahashi ◽

Masaaki Horiguchi

Keyword(s):

Mixed Function Oxidase ◽

Oxidase System ◽

Hepatic Microsomes ◽

Mixed Function Oxidase System

Download Full-text