Comparison between Plain Old Balloon Angioplasty and Drug-Eluting Stent Implantation for the Treatment of Stent Fracture

2015 ◽  
Vol 28 (4) ◽  
pp. 365-373 ◽  
Author(s):  
Satoru Mitomo ◽  
Toru Naganuma ◽  
Kensuke Takagi ◽  
Charis Costopoulos ◽  
Shotaro Nakamura ◽  
...  
Keyword(s):  
Balloon Angioplasty ◽  
Stent Implantation ◽  
Drug Eluting Stent ◽  
Stent Fracture ◽  
Drug Eluting ◽  
Plain Old Balloon Angioplasty

Comparison of 12-month angiographic outcomes between repeat drug-eluting stent implantation and drug-coated balloon treatment for restenotic lesion caused by stent fracture

2019 ◽  
Vol 34 (10) ◽  
pp. 1589-1594
Author(s):  
Yasunari Sakamoto ◽  
Masahiro Yamawaki ◽  
Motoharu Araki ◽  
Norihiro Kobayashi ◽  
Shinsuke Mori ◽  
...  
Keyword(s):  
Stent Implantation ◽  
Drug Eluting Stent ◽  
Stent Fracture ◽  
Drug Eluting ◽  
Drug Coated Balloon

scholarly journals Clinical outcomes and optimal treatment for stent fracture after drug-eluting stent implantation

2009 ◽  
Vol 53 (3) ◽  
pp. 422-428 ◽  
Author(s):  
Shin Eun Lee ◽  
Myung Ho Jeong ◽  
In Soo Kim ◽  
Jum Suk Ko ◽  
Min Goo Lee ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Stent Implantation ◽  
Optimal Treatment ◽  
Drug Eluting Stent ◽  
Stent Fracture ◽  
Drug Eluting

scholarly journals Impact of Coronary Stent Fracture on Restenotic Neointimal Tissue Characterization After Drug-Eluting Stent Implantation

2017 ◽  
Vol 58 (6) ◽  
pp. 861-867 ◽  
Author(s):  
Yasuhiro Uchida ◽  
Satoshi Ichimiya ◽  
Hideki Ishii ◽  
Hideo Oishi ◽  
Toshijiro Aoki ◽  
...  
Keyword(s):  
Stent Implantation ◽  
Tissue Characterization ◽  
Coronary Stent ◽  
Drug Eluting Stent ◽  
Stent Fracture ◽  
Drug Eluting

scholarly journals PREVALENCE AND CLINICAL OUTCOMES OF STENT FRACTURE AND RECOIL AFTER DRUG-ELUTING STENT IMPLANTATION

2011 ◽  
Vol 57 (14) ◽  
pp. E1835
Author(s):  
Naoki Saito ◽  
Kazushige Kadota ◽  
Mitsuru Yoshino ◽  
Koshi Miyake ◽  
Haruki Eguchi ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Stent Implantation ◽  
Drug Eluting Stent ◽  
Stent Fracture ◽  
Drug Eluting

scholarly journals Should We Still Do Plain Old Balloon Angioplasty following Rotational Atherectomy in Drug-Eluting Stent Era?

2020 ◽  
Author(s):  
Haojian Dong ◽  
Daisuke Hachinohe ◽  
Nie Zhiqiang ◽  
Yoshifumi Kashima ◽  
Jianfang Luo ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Balloon Angioplasty ◽  
Cox Regression ◽  
Rotational Atherectomy ◽  
Drug Eluting Stent ◽  
Metal Stents ◽  
Lesion Length ◽  
Total Occlusion ◽  
Drug Eluting ◽  
Plain Old Balloon Angioplasty

Abstract Background Drug-eluting stent (DES) is well known effective in severely calcified lesion after rotational atherectomy (ROTA). However, there are still some situations when metal stents should be avoided and plain old balloon angioplasty (POBA) emerges as the preferred option. The aim of present study is to explore that whether POBA is comparably effective to DES in large and calcified coronary pretreated by ROTA in clinical outcomes. Methods A retrospective analysis of consecutive patients treated for severely calcified lesions in large (≥ 3 mm) coronary using ROTA + DES or ROTA + POBA was performed. Major adverse cardiac events (MACE) including all cause/cardiac death and target lesion revascularization (TLR) at 1- and 2-year post-treatment, were compared between groups, with Cox regression analyses to identify independent predictors of TLR and MACE. Results The analysis included 285 cases in the ROTA + DES and 47 in the ROTA + POBA group, while no relevant between-group differences in clinical baseline characteristics were found. Of note, lesion length was greater in the ROTA + DES group (37.2 mm versus 19.3 mm, p < 0.001), with 8.4% lesions being chronic total occlusion in this group, but none in the ROTA + POBA group. The in-hospital/30-day mortality rate (5.3%, DES, and 6.4%, POBA), as well as the 12- and 24-month all-cause/cardiac mortality rate (9.3% and 7.7%, respectively) were not significantly different between groups. TLR rates were not significantly different between groups at 12-month (4.6%, DES, and 4.3%, POBA) and 24-month (5.3%, DES and 6.4%, POBA) respectively. Conclusions Outcomes were comparable for ROTA + DES and + POBA in severely calcified large coronary arteries intervention, with respect to mid-term death or TLR rate, especially for short lesion < 20 mm.

Endothelial Recovery in Bare Metal Stents and Drug-Eluting Stents on a Single-Cell Level

2021 ◽  
Author(s):  
Anne Cornelissen ◽  
Liang Guo ◽  
Raquel Fernandez ◽  
Michael C. Kelly ◽  
Christine Janifer ◽  
...  
Keyword(s):  
Single Cell ◽  
Balloon Angioplasty ◽  
Stent Implantation ◽  
Bare Metal Stents ◽  
Drug Eluting Stents ◽  
Metal Stents ◽  
Bare Metal ◽  
Single Cell Rna Sequencing ◽  
Drug Eluting ◽  
Plain Old Balloon Angioplasty

Objective: Healing processes, particularly reendothelialization, are essential for vascular homeostasis after plain old balloon angioplasty and stent implantation. Drug-eluting stents (DES) are commonly used for percutaneous coronary intervention because restenosis rates are reduced as compared with bare metal stents. However, in addition to understanding the nature of regenerated endothelial cells, concerns over incomplete stent healing persist, and the molecular effects of antiproliferative drug coatings on endothelium remain poorly understood. Approach and Results: We used the rabbit iliac artery model to analyze differences in stent endothelialization in bare metal stents and DES. Histology and immunohistochemistry confirmed that stent coverage was significantly greater in bare metal stents than in DES at 30 days after stent implantation. Single-cell RNA sequencing revealed a more immature transcriptomic signature of neointimal endothelial cell harvested from stented arteries in comparison with native and plain old balloon angioplasty–treated arteries. Whereas the genetic signature of bare metal stents was overall proangiogenic with enrichment of genes involved in endothelial proliferation, sprouting, and migration, as well as extracellular matrix assembly, DES-derived endothelial cell showed upregulation of genes associated with angiogenesis inhibition and endothelial activation. Conclusions: Single-cell RNA sequencing analysis identified unique transcriptional changes within regenerated endothelium after plain old balloon angioplasty and stent implantation. These data suggest unique endothelial transcriptional differences, which characterize the different response of the endothelium to vascular injury and may help explain why long-term responses in DES remain suboptimal.

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