Incidence of chest X‐ray abnormalities early in the third trimester of twin pregnancy and its relationship with the subsequent development of preeclampsia

Author(s):  
Kazunobu Yagi ◽  
Haruna Kawaguchi ◽  
Ryo Yamamoto ◽  
Shusaku Hayashi ◽  
Keisuke Ishii
2021 ◽  
Vol 25 ◽  
pp. e50
Author(s):  
Kazunobu Yagi ◽  
Haruna Kawaguchi ◽  
Ryo Yamamoto ◽  
Shusaku Hayashi ◽  
Keisuke Ishii

2016 ◽  
Vol 97 (6) ◽  
pp. 994-999 ◽  
Author(s):  
R F Khamitov ◽  
L Yu Pal’mova ◽  
K R Sulbaeva

Severe pneumonia is the actual problem of present respiratory medicine due to the pronounced impact on mortality and economic expenses of health care. For this reason the aim was to study the regional predictors of fatal severe pneumonia with subsequent development of guidelines for optimizing various aspects of diagnosis and treatment of these group of patients. Retrospective analysis of 62 case histories of admitted patients, who died from severe pneumonia during the calendar year, was performed. The results showed that lethal outcomes of severe pneumonia mostly occur in intensive care units. Analysis of performed laboratory and instrumental diagnostic procedures was conducted to reveal the most significant prognosis markers. The main mistakes in administering medications, firstly antimicrobial, were analyzed. Antibiotic therapy was proclaimed completely optimal only in 18% of cases. The analysis allows to make conclusions about the need for rational minimization of diagnostic complex for hospitalized patients with severe pneumonia with mandatory measurement of oxygen saturation, sputum study and chest X-ray in two projections directly on the first day. Along with timely correction of treatment these methods will allow optimizing the total cost of treatment. Ceftriaxone is a leading administered drug in severe pneumonia with lethal outcomes. Appearingly, first of all, it is determined by the absolute predominance of cheap generic drug forms in pharmaceutical market which do not provide adequate clinical efficiency. Underrated high potential of semisynthetic aminopenicillins in severe pneumonia treatment was identified.


2018 ◽  
Vol 45 (1) ◽  
pp. 226-229 ◽  
Author(s):  
Federico Ferrari ◽  
Giancarlo Tisi ◽  
Sara Forte ◽  
Enrico Sartori ◽  
Franco Odicino

Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1181
Author(s):  
Szymon Kozłowski ◽  
Anna Stelmaszczyk-Emmel ◽  
Iwona Szymusik ◽  
Aleksandra Saletra-Bielińska ◽  
Robert Brawura-Biskupski-Samaha ◽  
...  

Background: Preeclampsia occurs more often in dichorionic than in monochorionic twin pregnancy. We hypothesize that serum concentrations of biomarkers: placental growth factor (PlGF), serum soluble fms-like tyrosine kinase-1 (sFlt-1), and endoglin (Eng) differ between monochorionic and dichorionic twin pregnancies. Methods: A prospective observational study including 43 monochorionic and 36 dichorionic twin gestation was conducted. Blood samples were collected twice from all participants: between 11 + 0 and 13 + 6 and between 32 + 0 and 34 + 0 weeks of gestation. PlGF, sFlt-1 and Eng were measured using immnunoenzymatic assays. Results: We found a significantly higher concentration of sFlt-1 in dichorionic in comparison to monochorionic pregnancies in both the first and third trimesters. PlGF and sEng levels did not differ between mono- and dichorionic gestation in both study periods. sFlt-1 level was related to twin gestation chorionicity, while PlGF expression was not. PlGF, sFlt-1 and sEng concentrations increased significantly during gestation and were much higher in the third trimester compared to the values measured in the first trimester. Conclusions: Angiogenic biomarkers expression differ between dichorionic and monochorionic twin pregnancy. The sFlt-1 level is related to chorionicity of a twin gestation.


2003 ◽  
Vol 33 (1) ◽  
pp. 5-7 ◽  
Author(s):  
M C Groot ◽  
E J Buchmann

We investigate the problem of late diagnosis of twin pregnancy in Soweto, South Africa, where routine antenatal ultrasound is not available. One hundred consecutive pairs of twins were studied, using the notes of mothers who delivered twins at Chris Hani Baragwanath Hospital and the referring Soweto clinics. A positive history was found in 31 mothers (22 family history, nine previous history of twins). Six mothers did not attend for antenatal care. Twenty-five twin pregnancies were discovered at delivery, 15 of them in the second stage of labour, and 27 were diagnosed accidentally in the third trimester. Only 15 pregnancies were referred specifically for suspicion of twin pregnancy. Most twin pregnancies are detected only in the third trimester or at delivery. Until routine ultrasound is available to all pregnant women, the teaching of antenatal care in South Africa must give emphasis to clinical suspicion of twin pregnancy.


Praxis ◽  
2019 ◽  
Vol 108 (15) ◽  
pp. 991-996
Author(s):  
Ngisi Masawa ◽  
Farida Bani ◽  
Robert Ndege

Abstract. Tuberculosis (TB) remains among the top 10 infectious diseases with highest mortality globally since the 1990s despite effective chemotherapy. Among 10 million patients that fell ill with tuberculosis in the year 2017, 36 % were undiagnosed or detected and not reported; the number goes as high as 55 % in Tanzania, showing that the diagnosis of TB is a big challenge in the developing countries. There have been great advancements in TB diagnostics with introduction of the molecular tests such as Xpert MTB/RIF, loop-mediated isothermal amplification, lipoarabinomannan urine strip test, and molecular line-probe assays. However, most of the hospitals in Tanzania still rely on the TB score chart in children, the WHO screening questions in adults, acid-fast bacilli and chest x-ray for the diagnosis of TB. Xpert MTB/RIF has been rolled-out but remains a challenge in settings where the samples for testing must be transported over many kilometers. Imaging by sonography – nowadays widely available even in rural settings of Tanzania – has been shown to be a useful tool in the diagnosis of extrapulmonary tuberculosis. Despite all the efforts and new diagnostics, 30–50 % of patients in high-burden TB countries are still empirically treated for tuberculosis. More efforts need to be placed if we are to reduce the death toll by 90 % until 2030.


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