Expression of natural cytotoxicity receptor NKp46 on peripheral blood natural killer cells in women with a history of recurrent implantation failures

2020 ◽  
Author(s):  
Boris V. Dons'koi ◽  
Dariia V. Osypchuk ◽  
Viktor P. Chernyshov ◽  
Kseniia G. Khazhylenko
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Peripheral Blood ◽  
Natural Cytotoxicity ◽  
Killer Cells ◽  
Natural Cytotoxicity Receptor ◽  
History Of

Peripheral blood natural killer cells activation status determined by CD69 upregulation predicts implantation outcome in IVF

Immunobiology ◽  
2014 ◽  
Vol 219 (3) ◽  
pp. 167-171 ◽  
Author(s):  
Boris V. Dons’koi ◽  
Viktor P. Chernyshov ◽  
Vera Y. Sirenko ◽  
Galina V. Strelko ◽  
Dariia V. Osypchuk
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Peripheral Blood ◽  
Killer Cells ◽  
Activation Status

Fraction of the peripheral blood concentration of CD56+/CD16−/CD3− cells in total natural killer cells as an indication of fertility and infertility

2003 ◽  
Vol 80 ◽  
pp. 691-697 ◽  
Author(s):  
Vassiliki I Michou ◽  
Panagiotis Kanavaros ◽  
Vassilis Athanassiou ◽  
George B Chronis ◽  
Stelios Stabamas ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Peripheral Blood ◽  
Blood Concentration ◽  
Killer Cells

scholarly journals Glucocorticoid receptor expression on circulating leukocytes differs between healthy male and female adults

2017 ◽  
Vol 1 (2) ◽  
pp. 108-114 ◽  
Author(s):  
Kim D. Lu ◽  
Shlomit Radom-Aizik ◽  
Fadia Haddad ◽  
Frank Zaldivar ◽  
Monica Kraft ◽  
...  
Keyword(s):  
Gene Expression ◽  
Flow Cytometry ◽  
Sexual Dimorphism ◽  
Natural Killer Cells ◽  
Glucocorticoid Receptor ◽  
Natural Killer ◽  
Peripheral Blood ◽  
Healthy Adults ◽  
Peripheral Blood Mononuclear ◽  
Killer Cells

IntroductionThe glucocorticoid receptor (GR) is a key receptor involved in inflammatory responses and is influenced by sex steroids. This study measured GR expression on circulating leukocyte subtypes in males and females.MethodsA total of 23 healthy adults (12 female) participated in this study. GR expression was measured in leukocyte subtypes using flow cytometry. Peripheral blood mononuclear cell (PBMC) gene expression of GR (NR3C1), GR β, TGF-β1 and 2, and glucocorticoid-induced leucine zipper (GILZ) were determined by real-time polymerase chain reaction.ResultsLeukocyte GR was lower in females, particularly in granulocytes, natural killer cells, and peripheral blood mononuclear cells (p≤0.01). GR protein expression was different across leukocyte subtypes, with higher expression in eosinophils compared with granulocytes, T lymphocytes, and natural killer cells (p<0.05). There was higher gene expression of GR β in males (p=0.03).ConclusionsThis is the first study to identify sexual dimorphism in GR expression in healthy adults using flow cytometry. These results may begin to explain the sexual dimorphism seen in many diseases and sex differences in glucocorticoid responsiveness.

scholarly journals PB2387 CD56 BRIGHT/CD16- NATURAL KILLER CELLS COUNTS ARE HIGHER IN THE UMBILICAL CORD BLOOD THAN IN THE PERIPHERAL BLOOD FROM ADULTS

HemaSphere ◽  
2019 ◽  
Vol 3 (S1) ◽  
pp. 1062
Author(s):  
M. Barbosa ◽  
V. Molla ◽  
A. Mendroni Junior ◽  
M. Goncalves ◽  
E. Kimura ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Cord Blood ◽  
Natural Killer ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Peripheral Blood ◽  
Killer Cells
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