Oral retinoid, acitretin, is effective in the management of resistant recurrent vulval verrucous carcinoma: A case report

2020 ◽  
Vol 46 (10) ◽  
pp. 2179-2184
Author(s):  
Emily Fox ◽  
Mirna Elghobashy ◽  
Hamdi Hamad ◽  
Naiem Moiemen ◽  
Alaa El‐Ghobashy
2009 ◽  
Vol 123 (11) ◽  
Author(s):  
J Yiotakis ◽  
T Vamvakidis ◽  
E Iakovou ◽  
L Manolopoulos

AbstractIntroduction:Verrucous carcinoma is a variant of well differentiated squamous cell carcinoma characterised by an exophytic, warty growth which is slowly but locally invasive and which can cause extensive local destruction if left untreated.Case report:We report the first known case of veruccous carcinoma of the paranasal sinuses with rapid orbital invasion. A 58-year-old man presented with right-sided nasal obstruction, a huge right intranasal lesion, intractable dacryocystitis and cutaneous involvement of the nasolacrimal sac region. The tumour was partially removed using an endoscopic transnasal approach. Post-operatively, and while waiting for the histological result, the patient developed signs of rapid invasion of the orbit, with uniocular visual acuity deficit. He underwent combined radiochemotherapy, with a moderate response.Conclusion:Knowledge of the potentially aggressive nature of verrucous carcinoma may be helpful in early management of intraorbital invasion and salvaging of the eye.


2020 ◽  
Vol 58 (10) ◽  
pp. 971-974
Author(s):  
Thomas Frieling ◽  
Christian Kreysel ◽  
Michael Blank ◽  
Dorothee Müller ◽  
P. Euler ◽  
...  

Abstract Background Verrucous carcinoma of the esophagus is a rare disease leading to dysphagia, chest pain, and weight loss. The diagnosis is difficult because even repeated biopsies are often without tumor evidence. We present a patient with verrucous carcinoma of the esophagus and a literature review. Case report A 64-year-old patient with dysphagia and sore throat received esophagogastroduodenoscopy illustrating segmental circumferential verrucous inflammation and Candida esophagitis in the middle part of the esophagus. Repeated mucosal biopsies revealed reactive hyperkeratosis of the squamous epithelium with minimal atypia but without ulcera, eosinophilic esophagitis, or suspicion of cancer. Mucosal infection with adenovirus, herpes simplex virus 1, human papilloma virus types, and cytomegaly virus was ruled out. Veruccous carcinoma was detected finally by endoscopic mucosal resection. The patient was successfully treated by esophageal resection. Tumor stage was G1, pT1b, pN0, L0, V0, Pn0, R0. Conclusion The results suggest that macroscopic suspicion of verrucous esophageal carcinoma should lead to resections of larger tissue specimens by EMR to confirm the diagnosis.


2016 ◽  
Vol 28 (1) ◽  
pp. 70
Author(s):  
SantoshNagesh Holenarasipur ◽  
Tejavathi Nagaraj ◽  
ManjulaVenkat Batlahalli ◽  
YogeshLakkasetty Tathanahalli

2015 ◽  
Vol 10 (6) ◽  
pp. 3823-3825 ◽  
Author(s):  
YOSHITAKA KURISU ◽  
MOTOMU TSUJI ◽  
EMI YASUDA ◽  
MICHIKO FUJIWARA ◽  
SHINICHI MORIWAKI

2010 ◽  
Vol 89 (7) ◽  
pp. E21-E23 ◽  
Author(s):  
Frederick L. Durden ◽  
Charles E. Moore ◽  
Susan Muller

Verrucous carcinoma is a low-grade variant of squamous cell carcinoma reported to occur in all anatomic sites in the head and neck region, most commonly the oral cavity. The tumor grows locally invasive but is histologically benign and metastasizes rarely. To date, 22 cases of verrucous carcinoma involving the nasal cavity and/or the paranasal sinuses have been reported. We present a case of verrucous carcinoma involving the paranasal sinuses, nasal cavity, cranium, and orbit. This case highlights the difficulty of pathologic diagnosis and management options for a rare neoplastic lesion.


2017 ◽  
Vol 25 (5) ◽  
pp. 438-442 ◽  
Author(s):  
David John Tobias McArdle ◽  
John Patrick McArdle ◽  
Frances Lee ◽  
Emilio Dino Mignanelli

Author(s):  
Ankit Dhimole ◽  
N Anil Kumar ◽  
Meenakshi Bhasin ◽  
Anshuman Dixit

1983 ◽  
Vol 24 (4) ◽  
pp. 298-303 ◽  
Author(s):  
Anita N. Newman ◽  
Marc Colman ◽  
Steven A. Jayich

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