Fetal cloacal dysgenesis sequence presented with first trimester megacystis and associated umbilical cord abnormalities

2020 ◽  
Vol 46 (3) ◽  
pp. 527-530
Author(s):  
Selen Gursoy Erzincan ◽  
N. Cenk Sayin ◽  
Cihan Inan ◽  
Isil Uzun ◽  
Ozge Yapici Ugurlar ◽  
...  
Keyword(s):  
Umbilical Cord ◽  
First Trimester ◽  
Cloacal Dysgenesis

scholarly journals P25.09: First trimester umbilical cord cyst

2008 ◽  
Vol 32 (3) ◽  
pp. 400-400
Author(s):  
S. R. Kim ◽  
K. D. Ki ◽  
S. Y. Tong ◽  
J. M. Lee ◽  
E. H. Yoo ◽  
...  
Keyword(s):  
Umbilical Cord ◽  
First Trimester ◽  
Umbilical Cord Cyst

Three-Dimensional Sonographic Evaluation of the Position of the Fetal Conus Medullaris at First Trimester

2021 ◽  
pp. 1-8
Author(s):  
Ruben Ramirez Zegarra ◽  
Nicola Volpe ◽  
Evelina Bertelli ◽  
Greta Michela Amorelli ◽  
Luigi Ferraro ◽  
...  
Keyword(s):  
Abdominal Wall ◽  
Umbilical Cord ◽  
Interobserver Agreement ◽  
Interobserver Variability ◽  
First Trimester ◽  
3D Ultrasound ◽  
Conus Medullaris ◽  
Consecutive Series ◽  
Fetal Life ◽  
Umbilical Cord Insertion

<b><i>Objective:</i></b> The objective of this study was to assess the position of the conus medullaris (CM) at the first trimester 3D ultrasound in a cohort of structurally normal fetuses. <b><i>Methods:</i></b> This was a multicenter prospective study involving a consecutive series of structurally normal fetuses between 11 and 13 weeks of gestation (CRL between 45 and 84 mm). All fetuses were submitted to 3D transvaginal ultrasound using a sagittal view of the spine as the starting plane of acquisition. At offline analysis, the position of the CM was evaluated by 2 independent operators with a quantitative and a qualitative method: (1) the distance between the most caudal part of the CM and the distal end of the coccyx (CMCd) was measured; (2) a line perpendicular to the fetal spine joining the tip of the CM to the anterior abdominal wall was traced to determine the level of this line in relation to the umbilical cord insertion (conus to abdomen line, CAL). Interobserver agreement for the CCMd was evaluated. Linear regression analysis was used to determine the association between the CMCd and CRL, and a normal range was computed based on the best-fit model. The absence of congenital anomalies was confirmed in all cases after birth. <b><i>Results:</i></b> In the study period between December 2019 and March 2020, 143 fetuses were recruited. In 130 fetuses (90.9%), the visualization of the CM was feasible. The mean value of the CMCd was 1.09 ± 0.16 cm. The 95% limits of agreement for the interobserver variability in measurement of the CMCd were 0.24 and 0.26 cm. The interobserver variability based on the intra-class correlation coefficient (ICC) for the CCMd was good (ICC = 0.81). We found a positive linear relationship between the CCMd and CRL. In all these fetuses, the CAL encountered the abdominal wall at or above the level of the cord insertion. <b><i>Conclusion:</i></b> In normal fetuses, the assessment of the CM position is feasible at the first trimester 3D ultrasound with a good interobserver agreement. The CM level was never found below the fetal umbilical cord insertion, while the CMCd was noted to increase according to the gestational age, confirming the “ascension” of the CM during fetal life.

scholarly journals Unusual umbilical cord finding in a neonate

2019 ◽  
Vol 6 (6) ◽  
pp. 2685
Author(s):  
Antonieo Jude Raja ◽  
Sriambika K.
Keyword(s):  
Umbilical Cord ◽  
Congenital Anomalies ◽  
Cystic Lesion ◽  
Surgical Intervention ◽  
First Trimester ◽  
Chromosomal Anomalies ◽  
Umbilical Cord Cyst

Umbilical cord cyst refers to any cystic lesion that are associated with the umbilical cord. They are classified as true cysts or pseudocysts. True cysts are small remnants of the allantois, whereas false cysts originate from liquefaction of Wharton Jelly. In present case, cyst was diagnosed at birth without any associated congenital anomalies and resolved spontaneously within a few days requiring nil surgical intervention. Umbilical cord cysts deserve special attention since 20% of them, regardless of type, are associated with structural or chromosomal anomalies. Because of this, fetal karyotyping and amniocentesis should be considered when cysts persist beyond the first trimester.

Abstract 31: First Trimester Human Umbilical Cord Perivascular Cells (FTM HUCPVCs) Show Superior Angiogenic Potential in Angiogenic Potency Assays When Compared to Term HUCPVCs and Bone Marrow Stromal Cells

2016 ◽  
Vol 119 (suppl_1) ◽  
Author(s):  
Farwah Iqbal ◽  
Peter Szaraz ◽  
Jun Wu ◽  
Andree Gauthier-Fisher ◽  
Ren-Ke Li ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Umbilical Cord ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Aortic Ring ◽  
First Trimester ◽  
Marrow Stromal Cells ◽  
Human Umbilical Cord ◽  
Angiogenic Potential ◽  
Aortic Ring Assay

Introduction: Cell therapy employing pro-angiogenic cell types is a promising option for promoting revascularization of ischemic tissues. First trimester human umbilical cord perivascular cells (FTM HUCPVCs) are a young source of mesenchymal stromal cells (MSCs) that support blood vessels in the umbilical cord. Objective: We aimed to determine the angiogenic potential of FTM HUCPVCs using angiogenic potency assays and compare to older sources of MSCs: term HUCPVCs and bone marrow stromal cells (BMSCs). Methods: For the aortic ring assay, aortas were sectioned and embedded into Matrigel™. Fluorophore-labeled MSCs for testing were added to developing endothelial networks (Day0). MSC integration and network development were monitored by microscopy and quantification of endothelial networks was performed using ImageJ™ software (Day4) n=3. Using the Matrigel™ plug assay, 5.0 x10 5 MSCs were suspended with equal volumes of Matrigel™ and injected subcutaneously in 11-week-old nude mice and isolated after two weeks. Plug associated microvasculature was imaged and quantified n=3. Results: In the aortic ring assay, FTM HUCPVCs homed to endothelial networks and demonstrated greater endothelial cell coverage, when compared to term HUCPVCs and BMSCs. FTM HUCPVCs showed significantly greater network growth when compared to term HUCPVCs ( p ≤0.001), BMSCs ( p ≤0.001) and untreated endothelial networks ( p ≤0.001). FTM HUCPVC contributed to a significantly greater number of closed loops when compared to term HUCPVCs ( p ≤0.01), BMSCs ( p ≤0.001) and untreated networks ( p ≤0.05). At two weeks following injection of Matrigel plugs, FTM HUCPVC resulted in significantly greater blood vessel recruitment when compared to term HUCPVCs ( p ≤0.05), BMSCs ( p ≤0.01) and control media plugs ( p ≤0.01). Small tortuous blood vessels were found in significantly higher quantity in FTM HUCPVC injected plugs when compared to term HUCPVCs ( p ≤0.05), BMSCs (p ≤0.01) and media plugs ( p ≤0.001). Conclusions: These studies demonstrate that FTM HUCPVCs have superior potential to augment, both the initiation of capillary formation and the development of functional, perfusable blood vessels, highlighting their potential for tissue regeneration following ischemic injury.

First-trimester umbilical cord cysts.

Radiology ◽  
1992 ◽  
Vol 182 (3) ◽  
pp. 719-722 ◽  
Author(s):  
L K Skibo ◽  
E A Lyons ◽  
C S Levi
Keyword(s):  
Umbilical Cord ◽  
First Trimester

scholarly journals Umbilical Cord Entanglement: Diagnostic and Clinical Repercussions

2012 ◽  
Vol 6 (3) ◽  
pp. 225-232 ◽  
Author(s):  
Francisco Raga ◽  
Newton G Osborne ◽  
Luiz E Machado ◽  
Francisco Bonilla ◽  
Fernando Bonilla-Musoles ◽  
...  
Keyword(s):  
Umbilical Cord ◽  
Three Dimensional ◽  
First Trimester ◽  
Delivery Outcome ◽  
Entire Pregnancy ◽  
Pregnancy And Delivery ◽  
First Trimester Of Pregnancy ◽  
3D Ultrasonography ◽  
Umbilical Cord Entanglement

ABSTRACT The use of three-dimensional (3D) ultrasonography since the first trimester of pregnancy allows the diagnosis and follow-up of cord entanglement throughout the entire pregnancy and delivery. This technology permits a more accurate diagnosis when compared with two-dimensional (2D) ultrasonography or Doppler The vast majority of cord entanglements observed at the end of the first-trimester will persist during the entire pregnancy; delivery outcome is usually not affected by this finding except for cases in which multiple cord entanglement is diagnosed. How to cite this article Martínez-Aspas A, Raga F, Machado LE, Bonilla F Jr, Castillo JC, Osborne NG, Bonilla-Musoles F. Umbilical Cord Entanglement: Diagnostic and Clinical Repercussions. Donald School J Ultrasound Obstet Gynecol 2012;6(3):225-232.

Sign in / Sign up

Export Citation Format

Share Document