scholarly journals Long‐term impact of lymphadenectomies in patients with low‐grade, early‐stage uterine endometrial stroma sarcoma

2020 ◽  
Vol 46 (4) ◽  
pp. 654-662
Author(s):  
Yuanyuan Zhang ◽  
Ning Li ◽  
Wenpeng Wang ◽  
Hongwen Yao ◽  
Jusheng An ◽  
...  
Keyword(s):  
Early Stage ◽  
Low Grade ◽  
Endometrial Stroma ◽  
Long Term Impact ◽  
Endometrial Stroma Sarcoma

Long-Term Outcome and Prognostic Factors in Early-Stage Nodal Low-Grade Non-Hodgkin’s Lymphomas Treated with Radiation Therapy

2009 ◽  
Vol 185 (5) ◽  
pp. 288-295 ◽  
Author(s):  
Hans Theodor Eich ◽  
Martina Heimann ◽  
Hartmut Stützer ◽  
Jan Kriz ◽  
Marcel Reiser ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Prognostic Factors ◽  
Early Stage ◽  
Low Grade ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Hodgkin's Lymphomas

Sublobar resection versus lobectomy for early-stage pulmonary carcinoid tumors with three centimeters or less in size: A population-based study.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e21062-e21062
Author(s):  
Xiongfei Li ◽  
Fan Ren ◽  
Shikang Zhao ◽  
Yanye Wang ◽  
Dian Ren ◽  
...  
Keyword(s):  
Subgroup Analysis ◽  
Tumor Size ◽  
Early Stage ◽  
Population Based ◽  
Oncologic Outcomes ◽  
Low Grade ◽  
Sublobar Resection ◽  
Rank Tests ◽  
Log Rank Tests

e21062 Background: Pulmonary carcinoids (PCs), comprising of typical carcinoids (TCs) and atypical carcinoids (ACs), are rare low-grade malignant tumors and surgical resection is considered as the standard treatment for early stage PCs. However, it is not clear whether sublobar (Sub-L) resection of PCs would compromise the long-term oncologic outcomes. Here we investigate the equivalency of Sub-L resection versus lobectomy (Lobe) for patients with early stage PCs using the population-based Surveillance, Epidemiology, and End Results (SEER) registry. Methods: The clinical and survival data of early stage PC patients with less or equal 3cm diameter were retrieved. Kaplan-Meier method and log-rank tests were used to assess differences in overall survival (OS). We further performed the subgroup analysis by tumor size (T≤1cm, 1cm < T≤2cm, 2cm < T≤3cm) and patient age ( < 70y and ≥70y). To reduce the bias of inherent retrospective study, we also performed propensity score matching (PSM) analysis by 1:1 fixed ratio nearest neighbor matching using Matchit package in R. Results: In total of 2934 PC patients, including 2741 TCs and 193 ACs, were recruited. 1011(34.46%) and 1923(65.54%) patients received Sub-L resection and lobectomy, respectively. After PSM, there was no significant difference between Sub-L and Lobe group in terms of OS in PC patients (P = 0.33). From the cox regression analysis, it indicated that older age, male gender, larger tumor size, AC histology type and Sub-L surgery were associated with a worse OS. We further performed PSM analysis on TCs and ACs, respectively. For TC patients, it indicated that patients in Lobe group had a much better OS compared to those in Sub-L group (p = 0.0067). In the subgroup analysis, the log-rank tests showed that there was a significant survival advantage for lobectomy in comparison with Sub-L resection for the TC patients with diameter 2cm < T≤3cm (p = 0.0345), but not for those with diameter lower than 2cm. In the subgroup analysis of age, the log-rank test indicated that Lobe group in age < 70 had a better prognosis with statistical difference compared to Sub-L group (p = 0.0032). For ACs, there was no statistic difference between Sub-L and Lobe group after PSM analysis in all the subgroup investigations. Conclusions: Sublobar resection may not significantly compromise the long-term oncologic outcomes in early stage PC patients. However, there is a survival benefit of lobectomy in certain pathological type and population, such as TCs patients with tumor size more than 2cm and age lower than 70-year-old.

Long-term Impact of Cognitive Deficits and Epilepsy on Quality of Life in Patients With Low-Grade Meningiomas

Neurosurgery ◽  
2011 ◽  
Vol 69 (1) ◽  
pp. 72-79 ◽  
Author(s):  
Martin L Waagemans ◽  
David van Nieuwenhuizen ◽  
Monica Dijkstra ◽  
Miriam Wumkes ◽  
Clemens M F Dirven ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Deficits ◽  
Low Grade ◽  
Long Term Impact

Long-term impact of temozolomide on 1p/19q-codeleted low-grade glioma growth kinetics

2017 ◽  
Vol 136 (3) ◽  
pp. 533-539 ◽  
Author(s):  
C. Izquierdo ◽  
A. Alentorn ◽  
A. Idbaih ◽  
M. Simó ◽  
G. Kaloshi ◽  
...  
Keyword(s):  
Growth Kinetics ◽  
Low Grade Glioma ◽  
Low Grade ◽  
Glioma Growth ◽  
Long Term Impact

Crisis Phones - Suicide Prevention Versus Suggestion/Contagion Effects

Crisis ◽  
2015 ◽  
Vol 36 (3) ◽  
pp. 220-224 ◽  
Author(s):  
Steven Stack
Keyword(s):  
Suicide Prevention ◽  
Contagion Effects ◽  
Long Term Impact

Abstract. Background: There has been no systematic work on the short- or long-term impact of the installation of crisis phones on suicides from bridges. The present study addresses this issue. Method: Data refer to 219 suicides from 1954 through 2013 on the Skyway Bridge in St. Petersburg, Florida. Six crisis phones with signs were installed in July 1999. Results: In the first decade after installation, the phones were used by 27 suicidal persons and credited with preventing 26 or 2.6 suicides a year. However, the net suicide count increased from 48 in the 13 years before installation of phones to 106 the following 13 years or by 4.5 additional suicides/year (t =3.512, p < .001). Conclusion: Although the phones prevented some suicides, there was a net increase after installation. The findings are interpreted with reference to suggestion/contagion effects including the emergence of a controversial bridge suicide blog.

Sign in / Sign up

Export Citation Format

Share Document