Liver rupture in a 28‐year‐old primigravida with superimposed pre‐eclampsia and hemolysis, elevated liver enzyme levels, and low platelet count syndrome

2019 ◽  
Vol 45 (5) ◽  
pp. 1066-1070
Author(s):  
Till Kaltofen ◽  
Johanna Grabmeier ◽  
Tobias Weissenbacher ◽  
Klaus Hallfeldt ◽  
Sven Mahner ◽  
...  
Keyword(s):  
Platelet Count ◽  
Liver Enzyme ◽  
Elevated Liver Enzyme ◽  
Liver Rupture ◽  
Low Platelet Count

scholarly journals Lethal Pontine Hemorrhage in Postpartum Syndrome of Hemolysis, Elevated Liver Enzyme Levels, and Low Platelet Count

2005 ◽  
Vol 62 (7) ◽  
pp. 1150 ◽  
Author(s):  
Lawrence A. Zeidman ◽  
Aleksandar Videnovic ◽  
Lawrence P. Bernstein ◽  
Chimene A. Pellar
Keyword(s):  
Platelet Count ◽  
Liver Enzyme ◽  
Elevated Liver Enzyme ◽  
Pontine Hemorrhage ◽  
Low Platelet Count

scholarly journals Incidence and predictors of severe obstetric morbidity in a teaching hospital

2017 ◽  
Vol 5 (2) ◽  
pp. 44-48
Author(s):  
Rupa Bajagain ◽  
Rachana Saha Saha
Keyword(s):  
Intensive Care Unit ◽  
Platelet Count ◽  
Elevated Liver Enzyme ◽  
Maternal Deaths ◽  
Medical College ◽  
Obstetric Haemorrhage ◽  
Before And After ◽  
Obstetric Morbidity ◽  
Low Platelet Count ◽  
Disease Specific

Background: Evaluation of severe obstetric morbidity is an important aspect of optimum maternal health. Towards this, the Water stone and Mantel criteria have been used to know the incidence, predictors and causes of severe obstetric morbidity.Objectives: The study aimed to estimate incidence, predictors and causes of obstetric morbidity at Kathmandu Medical College and Teaching Hospital.Methods: A hospital-based prospective study was carried out from 1st September 2014 to 31st August 2015. All cases of severe obstetric morbidity according to the Mantel and Water stone criteria were identified. The socio-demographic and healthcare characteristics of extremely severe cases were compared with controls which included women who were admitted before and after the indexed cases.Results: There were 2270 deliveries during the study period, out of which 74 cases of severe obstetric morbidities were identified i.e. an incidence of 32.5 per 1000 deliveries. During the study period, there were three maternal deaths attributed to conditions studied. Disease-specific morbidities per 1000 deliveries were 18.9 for haemorrhage, 9.2 for severe pre-eclampsia, 0.88 for eclampsia, 0.44 for haemolysis elevated liver enzyme and low platelet count and 3.08 for sepsis. A total of 26 patients were admitted in Intensive care unit which was 1.145 per 100 of total deliveries.Conclusion: Severe obstetric morbidity and its relation to mortality may be more sensitive measures of pregnancy outcome than mortality alone. In this study, most events are related to obstetric haemorrhage and severe pre-eclampsia.Journal of Kathmandu Medical College Vol. 5, No. 2, Issue 16, Apr.-Jun., 2016, page: 44-48

ASSESSMENT OF THE PLATELET COUNT IN THE PREGNANT WOMEN IN IGIMS, PATNA, BIHAR

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Tanwi Singh ◽  
Anshuman Sinha
Keyword(s):  
Platelet Count ◽  
Pregnant Women ◽  
Screening Test ◽  
Low Cost ◽  
Medical Science ◽  
Cost Effective ◽  
Platelet Indices ◽  
Increased Risk ◽  
Low Platelet Count ◽  
Severity Of The Disease

The major risk associated with low platelet count in pregnancy is the increased risk of bleeding during the childbirth or post that. There is an increased blood supply to the uterus during pregnancy and the surgical procedure requires cutting of major blood vessels. Women with thrombocytopenia are at increased risk of losing excessive blood. The risk is more in case of caesarean delivery as compared to vaginal delivery. Hence based on above findings the present study was planned for Assessment of the Platelet Count in the Pregnant Women in IGIMS, Patna, Bihar. The present study was planned in Department of Pathology, Indira Gandhi Institute of Medical Science, Patna, Bihar, India. The present study was planned from duration of January 2019 to June 2019. In the present study 200 pregnant females samples received for the platelet estimation were enrolled in the present study. Clinically platelet indices can be a useful screening test for early identification of preeclampsia and eclampsia. Also platelet indices can assess the prognosis of this disease in pregnant women and can be used as an effective prognostic marker because it correlates with severity of the disease. Platelet count is a simple, low cost, and rapid routine screening test. Hence the data generated from the present study concludes that platelet count can be used as a simple and cost effective tool to monitor the progression of preeclampsia, thereby preventing complications to develop during the gestational period. Keywords: Platelet Count, Pregnant Women, IGIMS, Patna, Bihar, etc.

Quality of Life Improvements Following Eltrombopag Treatment in Children with Chronic Immune Thrombocytopenia: Case Report

2021 ◽  
Vol 104 (4) ◽  
pp. 672-675
Keyword(s):  
Quality Of Life ◽  
Platelet Count ◽  
Receptor Agonist ◽  
Immune Thrombocytopenia ◽  
Case Series ◽  
Thrombopoietin Receptor ◽  
Thrombopoietin Receptor Agonist ◽  
Low Platelet Count ◽  
Chronic Immune Thrombocytopenia

The present case series described six chronic immune thrombocytopenia patients (cITP), with a median age of 7.7 (7.0 to 13.0) years and low platelet count at 15,500 (7,000 to 20,000)/uL. They were suffering from bleeding symptoms and side effects of treatment. After enrollment, they were treated with thrombopoietin receptor agonist (eltrombopag). Five patients responded positively, showing a median platelet count of 115,000 (39,000 to 433,000)/uL. The median dose of eltrombopag used was 1.3 (0.8 to 2.2) mg/kg/day. The quality of life (QoL) improved for all patients, with their median overall score using a Pediatric QoL questionnaire showing 25.0% improvement. Median scores also showed improvements in each sphere of life functioning as physical (30.8%), emotional (26.4%), social (16.4%), and school (21.4%). The present report demonstrated that a select group of cITP patients, with low platelet count and bleeding symptoms, benefitted from treatment with eltrombopag, as shown by increased platelet counts and improved QoL. Keywords: Chronic ITP, Thrombopoietin receptor agonist, Children

EDTA‑dependent pseudothrombocytopenia in child (clinical case report)

2021 ◽  
pp. 51-54
Author(s):  
N. A. Sokolova ◽  
M. I. Savina ◽  
O. S. Shokhina
Keyword(s):  
Platelet Count ◽  
Clinical Case ◽  
Sodium Citrate ◽  
Ethylenediaminetetraacetic Acid ◽  
Hemorrhagic Diathesis ◽  
Platelet Dysfunction ◽  
Rare Presentation ◽  
Blood Samples ◽  
Low Platelet Count ◽  
Aggregation Of Platelets

Ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia is the phenomenon of a spurious low platelet count due to antiplatelet antibodies that cause platelet clumping in blood anticoagulated with EDTA. The aggregation of platelets in EDTA-dependent pseudothrombocytopenia is usually prevented by other anticoagulants, such as sodium citrate. EDTA-dependent pseudothrombocytopenia has never been associated with hemorrhagic diathesis or platelet dysfunction. In this article, a 2,5-year-old boy with EDTA-dependent pseudothrombocytopenia is presented because of rare presentation. We report that EDTA can induce platelet clumping, and thus spuriously low platelet counts. However, aggregation of platelets was not detected in blood samples with sodium citrate, and platelet count was normal.

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