Association of interleukin-1 receptor antagonist VNTR polymorphism and risk of pre-eclampsia in southeast Iranian population

2015 ◽  
Vol 42 (2) ◽  
pp. 142-147 ◽  
Author(s):  
Saeedeh Salimi ◽  
Milad Mohammadoo-Khorasani ◽  
Mahdieh Mousavi ◽  
Minoo Yaghmaei ◽  
Mojgan Mokhtari ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Interleukin 1 ◽  
Iranian Population ◽  
Vntr Polymorphism ◽  
Interleukin 1 Receptor Antagonist

Positive correlation between interleukin-1 receptor antagonist gene 86bp VNTR polymorphism and colorectal cancer susceptibility: a case-control study

2018 ◽  
Vol 67 (1) ◽  
pp. 151-156 ◽  
Author(s):  
Mostafa Ibrahimi ◽  
Maryam Moossavi ◽  
Ehsan Nazemalhosseini Mojarad ◽  
Mahsa Musavi ◽  
Milad Mohammadoo-khorasani ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Receptor Antagonist ◽  
Case Control Study ◽  
Cancer Susceptibility ◽  
Interleukin 1 ◽  
Case Control ◽  
Positive Correlation ◽  
Vntr Polymorphism ◽  
Interleukin 1 Receptor Antagonist ◽  
Control Study

scholarly journals Interleukin-1 receptor antagonist VNTR-polymorphism in inflammatory bowel disease

2002 ◽  
Vol 3 (7) ◽  
pp. 400-406 ◽  
Author(s):  
L Vijgen ◽  
M Van Gysel ◽  
A Rector ◽  
I Thoelen ◽  
N Esters ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Receptor Antagonist ◽  
Bowel Disease ◽  
Interleukin 1 ◽  
Vntr Polymorphism ◽  
Interleukin 1 Receptor Antagonist ◽  
Inflammatory Bowel

scholarly journals IL-1RN VNTR Polymorphism in Adult Dermatomyositis and Systemic Lupus Erythematosus

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Zornitsa Kamenarska ◽  
Gyulnas Dzhebir ◽  
Maria Hristova ◽  
Alexey Savov ◽  
Anton Vinkov ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Receptor Antagonist ◽  
Lupus Erythematosus ◽  
Interleukin 1 ◽  
Variable Number Tandem Repeat ◽  
Variable Number ◽  
Systemic Lupus ◽  
Vntr Polymorphism ◽  
Interleukin 1 Receptor Antagonist ◽  
Control Study

Polymorphisms in the cytokine genes and their natural antagonists are thought to influence the predisposition to dermatomyositis (DM) and systemic lupus erythematosus (SLE). A variable number tandem repeat (VNTR) polymorphism of 86 bp in intron 2 of the interleukin-1 receptor antagonist (IL-1RN) gene leads to the existence of five different alleles which cause differences in the production of both IL-1RA (interleukin-1 receptor antagonist) and IL-1β. The aim of this case-control study was to investigate the association between the IL-1RN VNTR polymorphism and the susceptibility to DM and SLE in Bulgarian patients. Altogether 91 patients, 55 with SLE and 36 with DM, as well as 112 unrelated healthy controls, were included in this study. Only three alleles were identified in both patients and controls ((1) four repeats, (2) two repeats, and (3) five repeats). The IL-1RN*2 allele (P=0.02, OR 2.5, and 95% CI 1.2–5.4) and the 1/2+2/2 genotypes were found prevalent among the SLE patients (P=0.05, OR 2.6, and 95% CI 1–6.3). No association was found between this polymorphism and the ACR criteria for SLE as well as with the susceptibility to DM. Our results indicate that the IL-1RN VNTR polymorphism might play a role in the susceptibility of SLE but not DM.

Interleukin 1 Receptor Antagonist Vntr Polymorphism and Pouchitis

1996 ◽  
Vol 90 (s34) ◽  
pp. 9P-9P
Author(s):  
PM Brett ◽  
F Herbst ◽  
N Yasuda ◽  
JY Yiannakou ◽  
RJ Nicholls ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Interleukin 1 ◽  
Vntr Polymorphism ◽  
Interleukin 1 Receptor Antagonist

scholarly journals Interleukin-1 Receptor Antagonist VNTR Polymorphism and Ovarian Cancer Susceptibility in Tunisian Women

JMED Research ◽  
2014 ◽  
pp. 1-9 ◽  
Author(s):  
Amira Ahmed ◽  
Sabrina Zidi ◽  
Ezzeddine Ghazouani ◽  
Amel Mezlini ◽  
Awatef Lagha ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Receptor Antagonist ◽  
Cancer Susceptibility ◽  
Interleukin 1 ◽  
Vntr Polymorphism ◽  
Interleukin 1 Receptor Antagonist
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