Assessment of maternal Doppler parameters of ophthalmic artery in fetuses with growth restriction in the third trimester of pregnancy: A case-control study

2015 ◽  
Vol 41 (9) ◽  
pp. 1330-1336 ◽  
Author(s):  
Nayana Alves De Brito Melo ◽  
Edward Araujo Júnior ◽  
Talita Micheletti Helfer ◽  
Ana Carolina Rabachini Caetano ◽  
Ana Cristina Perez Zamarian ◽  
...  
Keyword(s):  
Ophthalmic Artery ◽  
Case Control Study ◽  
Case Control ◽  
Growth Restriction ◽  
Third Trimester ◽  
The Third ◽  
Control Study

Anti-mullerian hormone concentration during the third trimester of pregnancy and puerperium: a longitudinal case–control study in normal and diabetic pregnancy

Endocrine ◽  
2014 ◽  
Vol 50 (1) ◽  
pp. 250-255 ◽  
Author(s):  
Sandro Gerli ◽  
Alessandro Favilli ◽  
Annalisa Brozzetti ◽  
Elisabetta Torlone ◽  
Brunella Pugliese ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Diabetic Pregnancy ◽  
Hormone Concentration ◽  
Third Trimester ◽  
The Third ◽  
Control Study

scholarly journals Persistence of decidual NK cells and KIR genotypes in healthy pregnant and preeclamptic women: a case-control study in the third trimester of gestation

2011 ◽  
Vol 9 (1) ◽  
pp. 8 ◽  
Author(s):  
Elly N Sánchez-Rodríguez ◽  
Sonia Nava-Salazar ◽  
C Adriana Mendoza-Rodríguez ◽  
Carlos Moran ◽  
Juan F Romero-Arauz ◽  
...  
Keyword(s):  
Nk Cells ◽  
Case Control Study ◽  
Case Control ◽  
Third Trimester ◽  
The Third ◽  
Control Study ◽  
Kir Genotypes

scholarly journals Analgesia in newborns: a case-control study of the efficacy of nutritive and non-nutritive sucking stimuli

CoDAS ◽  
2013 ◽  
Vol 25 (4) ◽  
pp. 365-368 ◽  
Author(s):  
Ana Henriques Lima ◽  
Ana Paula Hermont ◽  
Amélia Augusta de Lima Friche
Keyword(s):  
Case Control Study ◽  
Pain Scale ◽  
Case Control ◽  
Control Group ◽  
Pain Response ◽  
The Third ◽  
Nutritive Sucking ◽  
Lower Pain ◽  
Infant Pain ◽  
Control Study

PURPOSE: To verify the nutritive and non-nutritive stimuli efficacy in the newborn's response to pain during venipuncture. METHODS: The main sample was composed of 64 newborns that were randomly divided into three groups. The first group (n=20) received nutritive sucking stimulus that was performed through maternal breastfeeding. The second group (n=21) received non-nutritive sucking stimulus that was performed through the introduction of the researcher little finger in the newborn's oral cavity. The third group or control group (n=23) did not receive any analgesia stimulus. The newborns were evaluated using the Neonatal Infant Pain Scale, and the responses to painful stimuli were compared. RESULTS: The nutritive as well as non-nutritive suction methods provided a comforting effect, resulting in lower pain response scores (p<0.05). There was no difference between the analgesia provided by both methods (p>0.05). CONCLUSION: The nutritive and the non-nutritive sucking stimuli proved to be efficacious tools in relieving pain among newborns.

scholarly journals Maternal plasma fetuin-A levels in fetal growth restriction: A case-control study

2019 ◽  
Author(s):  
Mujde Can Ibano ◽  
Cem Yasar Sanhal ◽  
Seval Ozgu-Erdinc ◽  
Aykan Yucel
Keyword(s):  
Pregnant Women ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Plasma Levels ◽  
Case Control Study ◽  
Maternal Plasma ◽  
Case Control ◽  
Growth Restriction ◽  
Fetuin A ◽  
Control Study

Background: Higher Fetuin-A (FA) concentrations were found to be associated with obesity and there is an interest to the relation between maternal FA and pregnancy outcomes. Objective: In this study, our aim was to evaluate the association of maternal plasma levels of FA with fetal growth restriction (FGR). Materials and Methods: 41 pregnant women with FGR and 40 controls were recruited in this case-control study between July and November 2015. At the diagnosis of FGR, venous blood samples (10 cc) were obtained for FA analysis. Results: Maternal plasma FA levels were significantly higher in fetal growth-restricted pregnant women compared with controls (19.3 ± 3.0 ng/ml vs 25.9 ± 6.8 ng/ml, p = 0.001). Area under receiver operating characteristic curve analysis of FA in FGR was 0.815 (95% confidence interval (CI): 0.718-0.912, p < 0.001). The maternal FA levels with values more than 22.5 ng/ml had a sensitivity of about 73.17% (95% CI: 56.79- 85.25) and a specificity of about 82.5% (95% CI: 66.64-92.11) with positive and negative predictive values of about 81.08% (95% CI: 64.29-91.45) and 75% (95% CI: 59.35-86.30), respectively. Therefore, the diagnostic accuracy was obtained about 77.78%. Conclusion: The results of this study show higher maternal plasma levels of FA in FGR. Further studies are needed in order to demonstrate the long-term effects of FA in pregnancies complicated with FGR and early prediction of FGR.

scholarly journals Nerve growth factor is closely related to glucose metabolism, insulin sensitivity and insulin secretion in the second trimester: a case–control study in Chinese

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Mengyang Tang ◽  
Mingjuan Luo ◽  
Wenqian Lu ◽  
Rong Zhang ◽  
Wei Liang ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Case Control Study ◽  
Model Assessment ◽  
Second Trimester ◽  
Homeostasis Model Assessment ◽  
Third Trimester ◽  
Β Cell ◽  
The Third ◽  
Tnf Α ◽  
Control Study

Abstract Objective Inflammation-related factors have been shown to play a significant role throughout pregnancy. In this study, we aimed to explore the relationships between selected inflammatory cytokines and gestational diabetes (GDM) in Chinese pregnant women. Design and methods This was a 1:1 matched case–control study that included 200 pairs of subjects in the second trimester and 130 pairs of subjects in the third trimester. Serum levels of nerve growth factor (NGF), Interleukin-6 (IL-6), leptin, Interleukin-8 (IL-8), monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-alpha (TNF-α) and Interleukin-1beta (IL-1β) were measured by enzyme immunoassay. The associations of these inflammatory factors with metabolic parameters were analysed. Results In the second trimester, GDM patients had higher NGF levels and lower IL-8 levels than did normal controls (P < 0.001 and P = 0.015, respectively). However, in the third trimester, only lower leptin levels were observed in the GDM group (P = 0.031). Additionally, in the second trimester, NGF levels were not only positively associated with fasting, 1-h and 2-h glucose levels and the area under curve of glucose, but also positively related to insulin sensitivity and secretion, as suggested by fasting insulin, homeostasis model assessment of insulin resistance (HOMA-IR) and homeostasis model assessment index of β-cell secretion (HOMA-β) (all P < 0.05). Moreover, IL-6 and leptin levels were positively correlated with HOMA-IR and HOMA-β, and TNF-α levels were positively related to HOMA-IR (all P < 0.05). Except for the relationships between NGF and HOMA-β and TNF-α and HOMA-IR, the other correlations still existed even after adjusting for confounding factors (all P < 0.05). Conclusion In addition to the positive associations of IL-6 and leptin with insulin resistance and secretion, NGF was higher in the GDM patients and strongly linked to glucose metabolism, insulin resistance and pancreatic β cell function in Chinese pregnant women in the second trimester.

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