Cardiovascular risk markers and thyroid status in young Indian women with polycystic ovarian syndrome: A case-control study

2014 ◽  
Vol 40 (5) ◽  
pp. 1361-1367 ◽  
Author(s):  
Perla Sravan Kumar ◽  
Palghat Hariharan Ananthanarayanan ◽  
Soundravally Rajendiran
Keyword(s):  
Cardiovascular Risk ◽  
Polycystic Ovarian Syndrome ◽  
Case Control Study ◽  
Case Control ◽  
Risk Markers ◽  
Thyroid Status ◽  
Indian Women ◽  
Ovarian Syndrome ◽  
Control Study

scholarly journals Lipid Accumulation Product as a Marker of Cardiovascular Disease Risk among Women with Polycystic Ovarian Syndrome- A Hospital Based Case-control Study

2021 ◽  
Author(s):  
Roshni H Babu ◽  
Rakhi S Nair ◽  
Neelima Chakrapani
Keyword(s):  
Cardiovascular Risk ◽  
Polycystic Ovarian Syndrome ◽  
Case Control Study ◽  
Control Group ◽  
Continuous Variables ◽  
Risk Markers ◽  
Lipid Accumulation Product ◽  
Pcos Group ◽  
Ovarian Syndrome ◽  
Control Study

Introduction: Polycystic Ovarian Syndrome (PCOS) is the most frequent gynaecological endocrinopathy characterised mainly by anovulation and hyperandrogenism. Women with PCOS are at higher risk of developing Cardiovascular Disease (CVD) due to a number of risk factors associated with this disease. Obesity, especially central adipose tissue accumulation, plays a major role in the pathophysiology of this disease. Lipid Accumulation Product (LAP) is a simple, inexpensive index to estimate cardiovascular risk and is based on fasting triglyceride and Waist Circumference (WC). Aim: To find out the association between LAP and cardiovascular risk factors in women with PCOS. Materials and Methods: This case-control study was conducted in the Department of Biochemistry and Department of Gynaecology, Government Medical College, Thiruvananthapuram, Kerala, India. Study subjects included 48 women with PCOS and 48 age and Body Mass Index (BMI) matched controls. Clinical and demographic data and medical history were evaluated. Duration of the study was six months. Anthropometric measurements, Blood Pressure (BP) and biochemical parameters like Fasting Plasma Glucose (FPG), lipid profile were recorded. LAP was calculated using the formula-Female LAP= {waist (cm) -58} × Triglyceride (TG) concentration (mmol/L). The quantitative variables were expressed as mean and standard deviation. Comparison of continuous variables between two groups was analysed by unpaired t-test. Categorical variables were analysed by Chi-square test. Correlations between continuous variables were tested using the Pearson correlation or Spearman correlation coefficient (r) analysis. The p-value <0.05 was considered as statistically significant. Variables which were statistically significant in univariate analysis were subjected to multivariate analysis. Results: The results of this study showed that the PCOS group had significantly higher WC than BMI matched control group. PCOS group had significantly higher mean TG level (p<0.05), mean FPG level (p<0.05) and lower mean High Density Lipoprotein (HDL) level (p<0.05) than the control group. LAP value (p<0.001) was significantly higher in PCOS group compared to control group. The prevalence of Metabolic Syndrome (MetS) was higher in women with PCOS. LAP values too were significantly higher in PCOS women with MetS. All CVD risk parameters except age showed a significant relationship with LAP values. Multiple linear regression model was done and LAP (p<0.001) was found to be an independent risk factor for CVD, adjusting for other factors. Conclusion: The study results shows that there is a significant association between LAP and cardiovascular risk markers. High LAP index is associated with cardiovascular risk markers in PCOS women irrespective of obesity.

scholarly journals Mental and personality disorders in infertile women with polycystic ovary: a case-control study

2020 ◽  
Vol 20 (3) ◽  
pp. 1241-1249
Author(s):  
Mostafa Ahmadi ◽  
Mahbobeh Faramarzi ◽  
Zahra Basirat ◽  
Farzan Kheirkhah ◽  
Mohammad Chehrazi ◽  
...  
Keyword(s):  
Personality Disorders ◽  
Polycystic Ovarian Syndrome ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Infertile Women ◽  
The Mean ◽  
Ovarian Syndrome ◽  
Control Study

Background: Polycystic Ovarian Syndrome (PCOS) is one of the most common causes of infertility in women. Objective: The current study investigated mental and personality disorders in infertile women with and without PCOS. Methods: This case-control study evaluated 400 infertile women who referred to the Infertility Center in Babol city (North of Iran). Participants were categorized into the case group (201 PCOS) and the control group (199 without PCOS). All of the participants completed the Millon Clinical Multi-axial Inventory-III (MCMI-III). Results: The mean scores for clinical personality patterns were significantly higher for six personality disorders (schiz- oid, avoidant, antisocial, depressive, sadistic, and negativistic) and for three classes of severe personality disorder patterns (schizotypal, borderline, and paranoid) in infertile women with PCOS than in women without PCOS. The mean scores for eight clinical disorders (somatoform, manic disorder, dysthymia, alcohol-dependence, drug-dependence, post-trauma stress disorder, major depression, and delusion disorder) were also higher in infertile women with PCOS than in women without PCOS. Conclusion: The scores of many mental and personality disorders are higher in infertile women with PCOS than in women without PCOS. Thus, clinicians should prioritize recognizing and treating psychological problems of infertile women with PCOS. Keywords: Polycystic ovarian syndrome; infertility; personality disorders.

scholarly journals Effect of body weight on serum homocysteine level in patients with polycystic ovarian syndrome: A case control study

2016 ◽  
Vol 14 (2) ◽  
pp. 81-88 ◽  
Author(s):  
Ali Al- Gareeb ◽  
Wafaa Salah Abd Al- Amieer ◽  
Hayder M. Alkuraishy ◽  
Thabat J. Al- Mayahi ◽  
◽  
...  
Keyword(s):  
Body Weight ◽  
Polycystic Ovarian Syndrome ◽  
Case Control Study ◽  
Homocysteine Level ◽  
Case Control ◽  
Serum Homocysteine ◽  
Ovarian Syndrome ◽  
Control Study

scholarly journals Association of Oxidative Stress with Polycystic Ovarian Syndrome in Oman: A Case‐Control Study

2018 ◽  
Vol 32 (S1) ◽  
Author(s):  
Maha AH. Sulaiman ◽  
Yahya M. Al‐Farsi ◽  
Maha M. Al‐Khaduri ◽  
Jumana M. Saleh ◽  
Mostafa I. Waly
Keyword(s):  
Oxidative Stress ◽  
Polycystic Ovarian Syndrome ◽  
Case Control Study ◽  
Case Control ◽  
Ovarian Syndrome ◽  
Control Study

Body composition in women with premature ovarian insufficiency using hormone therapy and the relation to cardiovascular risk markers: A case‐control study

2020 ◽  
Vol 94 (1) ◽  
pp. 111-118
Author(s):  
Alberto T. A. Freitas ◽  
Andrea E. Donovan Giraldo ◽  
Gabriela Pravatta Rezende ◽  
Daniela A. Yela ◽  
Rodrigo M. Jales ◽  
...  
Keyword(s):  
Body Composition ◽  
Cardiovascular Risk ◽  
Hormone Therapy ◽  
Case Control Study ◽  
Case Control ◽  
Premature Ovarian Insufficiency ◽  
Risk Markers ◽  
Ovarian Insufficiency ◽  
Control Study

scholarly journals Polycystic ovarian syndrome (PCOS), related symptoms/sequelae, and breast cancer risk in a population-based case–control study

2016 ◽  
Vol 27 (3) ◽  
pp. 403-414 ◽  
Author(s):  
Jayeon Kim ◽  
Jennifer E. Mersereau ◽  
Nikhil Khankari ◽  
Patrick T. Bradshaw ◽  
Lauren E. McCullough ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Polycystic Ovarian Syndrome ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Ovarian Syndrome ◽  
Control Study
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