scholarly journals Impact of various sizing metrics on female donor to male recipient heart transplant outcomes

2021 ◽  
Author(s):  
Nicholas R. Hess ◽  
Gavin W. Hickey ◽  
Ibrahim Sultan ◽  
Yisi Wang ◽  
Arman Kilic
Keyword(s):  
Heart Transplant ◽  
Transplant Outcomes ◽  
Female Donor ◽  
Recipient Heart

Impact of tacrolimus variability on pediatric heart transplant outcomes

2021 ◽  
Author(s):  
Megan Sirota ◽  
Caroline Heyrend ◽  
Zhining Ou ◽  
Susan Masotti ◽  
Eric Griffiths ◽  
...  
Keyword(s):  
Heart Transplant ◽  
Transplant Outcomes ◽  
Pediatric Heart Transplant

Neonatal Heart Transplant Outcomes: A Single Institutional Experience

2021 ◽  
Author(s):  
Yihan Lin ◽  
Taylor J. Davis ◽  
Andres Zorrilla-Vaca ◽  
Brandon M. Wojcik ◽  
Shelley D. Miyamoto ◽  
...  
Keyword(s):  
Heart Transplant ◽  
Transplant Outcomes ◽  
Neonatal Heart ◽  
Institutional Experience

Abstract 12932: The ABO Blood Group of Donor Hearts Determine the Impact of Cold Preservation Duration on Heart Transplant Outcomes

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Paul C TANG ◽  
Jonathan W Haft ◽  
IENGLAM LEI ◽  
Zhong Wang ◽  
Eugene Chen ◽  
...  
Keyword(s):  
Heart Transplant ◽  
Allograft Rejection ◽  
Blood Type ◽  
Graft Dysfunction ◽  
Ischemic Time ◽  
Cold Preservation ◽  
Transplant Outcomes ◽  
Chronic Allograft Rejection ◽  
Propensity Matching ◽  
The Impact

Background: Tolerance of donor hearts of different ABO blood types to allograft ischemic time has not been previously examined. Objectives: We determined the impact of allograft ischemic time on heart transplant outcomes with differing ABO donor organ types. Methods: We identified 32,454 heart transplants (2000-2016) from the United Network for Organ Sharing database. Continuous variables were analyzed with t-test and categorical variables were compared with Chi-squared test. Survival was determined using log-rank or Cox regression tests. Propensity matching adjusted for preoperative variables. Results: Comparing allograft ischemic times <4 hours (hr, n=6579) versus ≥4hr (n=25,875), the odds ratio (OR) for death at 15 years following prolonged allograft ischemic time (≥4hrs) for blood type O, A, B, and AB were 1.106 (P<0.001), 1.062 (P<0.001), 1.059 (P=0.062), 1.114 (P=0.221), respectively. Unadjusted data demonstrated higher mortality for transplantation of O versus non-O donor hearts for allograft ischemic times ≥4 hours (OR=1.164, P<0.001). Following propensity matching, O donor hearts continued to have worse survival if preserved for ≥4hrs (OR=1.137, P=0.008), but not if allograft ischemic time was <4hrs (OR=1.042, P=0.113). In a matched group with ≥4hrs of allograft ischemic time, patients receiving O donor organs were more likely to experience death from primary allograft dysfunction (2.5% vs 1.7%, P=0.052) and chronic allograft rejection (1.9% versus 1.1%, P=0.021). No difference in death from primary allograft graft dysfunction or chronic allograft rejection was seen with <4hr of allograft ischemic time (P>0.150). Conclusions: Compared with non-O hearts, transplantation with O donor hearts stored for ≥4hrs leads to worse survival, with higher rates of primary graft dysfunction and chronic rejection. Caution should be practiced when considering donor hearts with the O blood type when extended cold preservation times are anticipated.

Heart Transplant Outcomes for Patients with Cardiac Sarcoidosis

2020 ◽  
Vol 39 (4) ◽  
pp. S143
Author(s):  
G.S. Liu ◽  
A.M. Wolfson ◽  
J. Nattiv ◽  
P.A. Genyk ◽  
D. Vucicevic ◽  
...  
Keyword(s):  
Heart Transplant ◽  
Cardiac Sarcoidosis ◽  
Transplant Outcomes

Standardized Donor Acceptance Criteria: Impact on Pediatric Waitlist and Heart Transplant Outcomes

2019 ◽  
Vol 38 (4) ◽  
pp. S472
Author(s):  
N. Baez ◽  
R. Kirk ◽  
R. Davies ◽  
D. Sutcliffe ◽  
M. Bano ◽  
...  
Keyword(s):  
Heart Transplant ◽  
Acceptance Criteria ◽  
Transplant Outcomes
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