scholarly journals Multi‐disciplinary frameworks for the treatment of primary cardiac sarcoma

2021 ◽  
Author(s):  
Randy M. Stevens ◽  
Ayaka Silverman ◽  
Judy Pascasio ◽  
Jie Sun ◽  
Amy Throckmorton ◽  
...  
Keyword(s):  
Primary Cardiac Sarcoma

scholarly journals Combined treatment for a large primary cardiac sarcoma: a case report

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Shinji Akishima ◽  
Akito Imai ◽  
Yoshiharu Enomoto ◽  
Osamu Shigeta
Keyword(s):  
Case Report ◽  
Combined Treatment ◽  
Primary Cardiac Sarcoma ◽  
Large Primary

Intimal Sarcoma Is the Most Frequent Primary Cardiac Sarcoma

2014 ◽  
pp. 1 ◽  
Author(s):  
Agnès Neuville ◽  
Françoise Collin ◽  
Patrick Bruneval ◽  
Marie Parrens ◽  
Françoise Thivolet ◽  
...  
Keyword(s):  
Intimal Sarcoma ◽  
Primary Cardiac Sarcoma

scholarly journals Multidisciplinary approach to rare primary cardiac sarcoma: a case report and review

BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Audrone Vaitiekiene ◽  
Domas Vaitiekus ◽  
Laura Urbonaite ◽  
Antanas Jankauskas ◽  
Justina Portacenko ◽  
...  
Keyword(s):  
Case Report ◽  
Multidisciplinary Approach ◽  
Primary Cardiac Sarcoma

Treatment and Outcomes in Adult Patients with Primary Cardiac Sarcoma: The British Columbia Cancer Agency Experience

2009 ◽  
Vol 16 (12) ◽  
pp. 3358-3365 ◽  
Author(s):  
Pauline T. Truong ◽  
Stuart O. Jones ◽  
Benjamin Martens ◽  
Cheryl Alexander ◽  
Matthew Paquette ◽  
...  
Keyword(s):  
British Columbia ◽  
Adult Patients ◽  
British Columbia Cancer Agency ◽  
Cancer Agency ◽  
Primary Cardiac Sarcoma

Primary Cardiac Sarcoma

CHEST Journal ◽  
1998 ◽  
Vol 114 (2) ◽  
pp. 648-652 ◽  
Author(s):  
Benjamin Movsas ◽  
Julie Teruya-Feldstein ◽  
Judy Smith ◽  
Eli Glatstein ◽  
Alan H. Epstein
Keyword(s):  
Primary Cardiac Sarcoma

UNUSUAL CASE OF PRIMARY CARDIAC SARCOMA

2011 ◽  
Vol 22 ◽  
pp. S84-S85
Author(s):  
M. Salem ◽  
J. Pell ◽  
D. Richens ◽  
C. Foster
Keyword(s):  
Unusual Case ◽  
Primary Cardiac Sarcoma

Incidence of brain metastases and overall survival in patients with primary cardiac sarcoma: A retrospective case series.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 10584-10584
Author(s):  
Maryann Shango ◽  
Lili Zhao ◽  
Monika Leja ◽  
Jonathan B. McHugh ◽  
Scott Schuetze ◽  
...  
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Case Series ◽  
Cancer Center ◽  
R0 Resection ◽  
Left Heart ◽  
Retrospective Case ◽  
Imaging Evaluation ◽  
Presenting Symptoms ◽  
Primary Cardiac Sarcoma

10584 Background: Primary cardiac sarcoma (PCS) is the most common primary cardiac malignancy, but is a rare primary site of sarcoma. We present 21 cases from a tertiary care center to better understand this uncommon malignancy. Methods: A cancer center-based registry and pathology database were searched to identify pts diagnosed with PCS from 1992-2013 at University of Michigan. Kaplan-meier method was used to estimate survival. Cox proportional hazard model was used to associate variables to occurrence of metastases (mets) or death. Results: Atotal of 21 pts (F12, 9M) with PCS were identified, median age 36 (range 11-74). The most common presenting symptoms included dyspnea (16) and chest pain (6; 5 with associated pericardial effusion). Histologies included: angiosarcoma (9), leiomyosarcoma (4), undifferentiated pleomorphic (3), spindle cell (2), fibrosarcoma (1), rhabdomyosarcoma (1) and synovial (1). Sites of origin were R atrium (7), R ventricle (2), L atrium (10) and pericardium (2). Ten pts presented with mets; most common sites were lung (8), liver (2), brain (2), pancreas (2) and bone (2). Surgery was attempted in 12 pts, achieving 1 R0 resection. Pts received a median of 1 (0-7) systemic therapies. Median overall (OS) was 12.6 mos (range 3-79) from diagnosis. Pts without prior surgery were more likely to have mets or death (p=0.038). Brain mets were common, occurring in 7 of 21 pts after a median of 7 mos (range 1-75) from diagnosis. Median OS after diagnosis of brain mets was 8 mos. Of the 7 pts who developed brain metastasis, 5 had PCS originating in the left heart. Of the 2 pts with PCS in the right heart, one was evaluated for and had a right to left shunt. The likelihood of developing brain mets did not correlate with age, chemotherapy, or surgery. Conclusions: PCS portends an extremely poor prognosis, marked by inability to achieve complete resection and a high incidence of disseminated disease at diagnosis. Metastatic disease to the brain was much more common in PCS (33%) as compared to STS of any origin (approximately 1-8%), particularly in pts with PCS originating in the left heart. Clinicians should have a low threshold for brain imaging evaluation of PCS pts.

scholarly journals Respiratory Failure in an Adolescent with Primary Cardiac Sarcoma

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Daniel Angeli ◽  
Stephen J. Angeli
Keyword(s):  
Heart Failure ◽  
Respiratory Failure ◽  
Lung Disease ◽  
Adult Population ◽  
Correct Diagnosis ◽  
Adolescent And Young Adult ◽  
Cardiac Tumors ◽  
Intravenous Contrast ◽  
Tertiary Center ◽  
Primary Cardiac Sarcoma

We report a case of progressive respiratory failure secondary to primary cardiac sarcoma masquerading as primary lung disease. An 18-year-old female presented to our hospital emergency department with progressive cough, dyspnea, and hemoptysis. She was treated for primary lung infection without improvement and had respiratory failure with endotracheal intubation by the third hospital day. An “intermediate” plasma brain natriuretic protein (BNP) of 216 pg/mL did not raise concerns about a heart failure diagnosis and may have delayed the correct diagnosis. Computed tomography of the chest with intravenous contrast was performed on the fifth hospital day and revealed a cardiac mass. A transthoracic echocardiogram confirmed a large left atrial mass that was obstructing mitral inflow. She was transferred to a tertiary center for emergency cardiac surgery. Primary cardiac tumors are a rare and treatable cause of heart failure in adolescent and young adult patients. Presentation can be confused with primary lung disease and must be suspected early. Plasma BNP cutoff levels used in the adult population should not be extrapolated to adolescents, as levels, both normal and abnormal, are significantly lower in this group of patients.

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