scholarly journals Heart transplantations amidst the COVID‐19 pandemic: “In the midst of chaos, there is also opportunity”

2021 ◽  
Author(s):  
Andrea Amabile ◽  
Arnar Geirsson
Keyword(s):  
Heart Transplantations

1000 heart transplantations in 6 different eras of innovation at a single center

2009 ◽  
Vol 56 (S 01) ◽  
Author(s):  
S Kofler ◽  
B Meiser ◽  
A Bigdeli ◽  
D Kellerer ◽  
M König ◽  
...  
Keyword(s):  
Single Center ◽  
Heart Transplantations

GENOMICS OF MYOCARDIAL SAMPLES FROM HEART TRANSPLANTATIONS CANDIDATES SUPPORTED BY PULSATILE AND NON-PULSATILE VENTRICULAR ASSIST DEVICES

ASAIO Journal ◽  
2006 ◽  
Vol 52 (2) ◽  
pp. 52A
Author(s):  
Hendrik Milting ◽  
Peter Ellinghaus ◽  
Donatella d???Urso ◽  
Sonja Steppan ◽  
Latif Arusoglu ◽  
...  
Keyword(s):  
Ventricular Assist Devices ◽  
Ventricular Assist ◽  
Assist Devices ◽  
Heart Transplantations

Natural History of Circadian Blood Pressure and Heart Rate Pattern in Patients Who Underwent Heart Transplantations

1993 ◽  
Vol 7 (4) ◽  
pp. 246-252 ◽  
Author(s):  
Pietro Cugini ◽  
Piernatale Lucia ◽  
L. Di Palma ◽  
Giovanni Scibilia ◽  
Anna Rita Cioli ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Natural History ◽  
Heart Transplantations ◽  
Circadian Blood Pressure ◽  
History Of ◽  
Heart Rate Pattern

Anaesthesia in heart transplantations in neonates and infants

1994 ◽  
Vol 8 (5) ◽  
pp. 24
Author(s):  
B. Zickmann ◽  
J. Boldt ◽  
Ch. Knothe ◽  
J. Bauer ◽  
F. Dapper ◽  
...  
Keyword(s):  
Heart Transplantations ◽  
Neonates And Infants

Future Perspectives of a Childrens' Heart Center after More Than 200 Pediatric Heart Transplantations

2016 ◽  
Vol 64 (S 01) ◽  
Author(s):  
K. Valeske ◽  
N. Mazhari ◽  
C. Yerebakan ◽  
M. Müller ◽  
J. Thul ◽  
...  
Keyword(s):  
Future Perspectives ◽  
Heart Transplantations ◽  
Heart Center

Heart Transplantation

2014 ◽  
Author(s):  
Michael M. Givertz
Keyword(s):  
Heart Failure ◽  
Heart Transplantation ◽  
Heart Transplant ◽  
Cardiac Allograft Vasculopathy ◽  
Cardiac Allograft ◽  
Transplant Recipients ◽  
Allograft Vasculopathy ◽  
Adult Heart ◽  
Heart Transplantations ◽  
Heart Transplant Recipients

Heart failure is a major public health problem with significant associated morbidity and mortality. Heart transplantation remains the standard of care for highly selected patients with end-stage heart failure and absence of contraindications to transplantation. This chapter discusses indications and contraindications for transplantation; recipient evaluation, selection, and management; donor selection; timing of the procedure and surgical technique; medical management, including immunosuppression, prevention and treatment of infections, and other standard or preventive therapy; late complications; and functional status and long-term survival. Tables describe patient referral to a specialized center for heart transplantations; guidelines of indications for cardiac transplantation; organ dysfunction; pretransplantation evaluation; waiting lists; therapeutic options for patients with advanced or refractory heart failure; treating highly sensitized patients; suggested vaccinations; guidelines for donor hearts with severe infection; high-risk donor behavior; hemodynamic effect of commonly used parenteral agents; frequency of follow-up evaluations; revised International Society for Heart and Lung Transplantation (ISHLT) formulation for diagnosis of cardiac allograft rejection and suggested treatment; function of immunosuppressive agents; administration, dosing, monitoring, and adverse effects of commonly used immunosuppressants; common agents that interfere with tacrolimus and cyclosporine; cytomegalovirus prophylaxis and valganciclovir based on estimated renal function; cumulative morbidity rates in adult heart transplant survivors; and therapies to prevent and treat osteoporosis posttransplantation. Figures depict the progression of heart failure; change in functional status over time in patients with chronic heart failure; US heart transplantations in 2012; percentage of US adult wait-listed patients who received a donor heart transplant within a year and donation rates by state; bicaval surgical technique; endomyocardial biopsies; timeline of infection following solid-organ transplantation; cardiac allograft vasculopathy; and squamous cell carcinomas in a heart transplant patient. Graphs show adult worldwide heart transplantation volume from 1982 to 2010; changing characteristics of US adult heart transplant recipients; relative risk of death and development of cardiac allograft vasculopathy; posttransplantation immunosuppression at 1 and 5 years in the ISHLT Registry; older donor age and risk of developing cardiac allograft vasculopathy; freedom from malignancy in the ISHLT Registry; employment status of adult heart transplant recipients; adult heart transplant survival; and patient survival among US heart transplant recipients by gender and race. This review contains 18 highly rendered figures, 20 tables, and 109 references.

Experience With Heart Transplantation in Children

PEDIATRICS ◽  
1987 ◽  
Vol 79 (1) ◽  
pp. 138-146 ◽  
Author(s):  
F. Jay Fricker ◽  
Bartley P. Griffith ◽  
Robert L. Hardesty ◽  
Alfredo Trento ◽  
Larry M. Gold ◽  
...  
Keyword(s):  
Heart Disease ◽  
Heart Transplantation ◽  
Dilated Cardiomyopathy ◽  
Chronic Rejection ◽  
Antithymocyte Globulin ◽  
The Other ◽  
Right Atrial ◽  
Heart Transplants ◽  
Heart Transplantations ◽  
Early Results

Between March 1981 and March 1986, 200 orthotopic heart transplantations were performed at the University of Pittsburgh. Fourteen of those procedures were carried out in children 2 to 16 years of age. Two children received combined liver and heart transplants; one because of familial hypercholesterolemia with associated ischemic heart disease, and the other because of dilated cardiomyopathy associated with intrahepatic biliary atresia. Eight patients had dilated cardiomyopathy, and two had myocarditis. Two had heart transplantations for congenital heart disease: one had multiple muscular ventricular septal defects repaired in infancy and had an associated cardiomyopathy, and the other developed a cardiomyopathic ventricle from a congenital right coronary artery to right atrial fistula. Chronic immune suppression consisted 0.2 to 0.5 mg/kg/d of prednisone and 5 to 50 mg/kg/d cyclosporine, with the addition of antithymocyte globulin for unresolved moderate or severe acute rejection. There were three early postoperative deaths: one from intracranial bleeding, one from Pseudomonas mediastinitis, and one from ischemic injury to transplanted organs. Early postoperative complications included reversible renal failure, hypertension, and seizures. Late problems were related to allograft rejection and side effects of cyclosporine and corticosteroids. Significant rejection episodes occurred in all patients surviving longer than 2 weeks, with seven requiring antithymocyte globulin. Two patients died 8 months following transplantation of severe acute and chronic rejection; another patient required retransplantation for ischemic cardiomyopathy resulting from chronic rejection but subsequently died of recurring rejection 3 months after the second transplantation. Eight surviving patients 4 months to 4 years after heart transplantation had returned to age-appropriate activities. These early results have encouraged the authors to continue to use heart transplantation as a viable alternative in children with terminal heart disease.

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