scholarly journals Intestinal fatty acid‐binding protein and acute gastrointestinal injury grade in postoperative cardiac surgery patients

2021 ◽  
Author(s):  
Jenny Seilitz ◽  
Måns Edström ◽  
Alhamsa Kasim ◽  
Kjell Jansson ◽  
Birger Axelsson ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Gastrointestinal Injury ◽  
Injury Grade ◽  
Acute Gastrointestinal Injury

scholarly journals Prevention of gastrointestinal injury by using glutamine in cardiac surgery

2015 ◽  
Vol 18 (3) ◽  
pp. 19 ◽  
Author(s):  
S. M. Yefremov ◽  
V. A. Shmyrev ◽  
M. N. Deryagin ◽  
I. A. Kornilov ◽  
A. N. Shilova ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Intestinal Damage ◽  
Double Blind ◽  
Fatty Acid Binding ◽  
Double Blind Placebo ◽  
Intestinal Integrity ◽  
Acid Binding Protein

A pilot double-blind, placebo-controlled, randomized study The aim of this study was to evaluate the efficiency of perioperative administration of glutamine to preserve intestinal integrity in patients undergoing cardiac surgery. 24 patients scheduled for elective coronary artery bypass surgery under cardiopulmonary bypass were included in this prospective, randomized, double-blind placebo controlled pilot study. 12 patients were randomized to receive glutamine (20% solution of N(2)-L-alanyl-L-glutamine) 0.4 g/kg a day, while the remaining 12 patients received an equivalent placebo dose (0.9% solution of NaCl). Infusion of glutamine/placebo was started after the induction of anesthesia and was continued for 24 hours. The primary end-point was dynamics of plasma concentration of a specific marker of intestinal damage, intestinal fatty acid binding protein (I-FABP). The secondary end-points were liver fatty acid binding protein (L-FABP), alpha glutathione s-transferase (aGST), heat shock protein 70 (HSP 70). There were no between-group differences of all the studied biochemical parameters at any stage of the study. Plasma I-FABP levels (median [25-75 percentile]) were markedly elevated during CPB and remained the same postoperatively: 962 (577-2 067) and 883 (444-1 625) г/ml 5 min after un-clamping of aorta, 2203 (888-3 429) and 1 560 (506-2 657) г/ml <sup>2</sup> hours post-bypass, 897 (555-1 424) and 794 (505-951) г/ml 6 hours post-bypass in the GLN and control groups respectively. Perioperative administration of glutamine in dose of 0.4 g/kg a day does not appear to preserve intestinal integrity in low risk cardiac surgery patients.

scholarly journals Plasma and Urinary Levels of Heart Fatty Acid-Binding Protein in Patients Undergoing Cardiac Surgery

2000 ◽  
Vol 64 (1) ◽  
pp. 18-22 ◽  
Author(s):  
Nobuhiko Hayashida ◽  
Shingo Chihara ◽  
Koji Akasu ◽  
Takeshi Oda ◽  
Eiki Tayama ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Urinary Levels

scholarly journals Liver fatty acid-binding protein as a biomarker of acute kidney injury after cardiac surgery

2008 ◽  
Vol 73 (4) ◽  
pp. 465-472 ◽  
Author(s):  
D. Portilla ◽  
C. Dent ◽  
T. Sugaya ◽  
K.K. Nagothu ◽  
I. Kundi ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Cardiac Surgery ◽  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Kidney Injury ◽  
Liver Fatty Acid ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

scholarly journals Does heart-type fatty acid-binding protein predict clinical outcomes after pediatric cardiac surgery?

2017 ◽  
Vol 10 (3) ◽  
pp. 245 ◽  
Author(s):  
WardY Vanagt ◽  
EgmondS Evers ◽  
Varsha Walavalkar ◽  
Suresh Pujar ◽  
Latha Balasubramanian ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Fatty Acid ◽  
Clinical Outcomes ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Pediatric Cardiac Surgery ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

scholarly journals Perioperative heart-type fatty acid binding protein is associated with acute kidney injury after cardiac surgery

2015 ◽  
Vol 88 (3) ◽  
pp. 576-583 ◽  
Author(s):  
Jennifer A. Schaub ◽  
Amit X. Garg ◽  
Steven G. Coca ◽  
Jeffrey M. Testani ◽  
Michael G. Shlipak ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Cardiac Surgery ◽  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Kidney Injury ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

scholarly journals Perioperative heart-type fatty acid binding protein levels in atrial fibrillation after cardiac surgery

Heart Rhythm ◽  
2013 ◽  
Vol 10 (2) ◽  
pp. 153-157 ◽  
Author(s):  
Florian Rader ◽  
Akshat C. Pujara ◽  
Gregory Pattakos ◽  
Jeevanantham Rajeswaran ◽  
Liang Li ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cardiac Surgery ◽  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Protein Levels ◽  
Acid Binding Protein
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