Acute type A aortic dissection in‐hours versus out‐of‐hours: A systematic review and meta‐analysis

2020 ◽  
Vol 35 (12) ◽  
pp. 3432-3439 ◽  
Author(s):  
Steven Toh ◽  
Dominic Choon Men Yew ◽  
Jia Jin Choong ◽  
Tze Lin Chong ◽  
Amer Harky
Author(s):  
Holly N. Smith ◽  
Munir Boodhwani ◽  
Maral Ouzounian ◽  
Richard Saczkowski ◽  
Alexander J. Gregory ◽  
...  

2019 ◽  
Vol 29 (5) ◽  
pp. 766-775 ◽  
Author(s):  
Jinlin Wu ◽  
Yan Huang ◽  
Juntao Qiu ◽  
Bilal Saeed ◽  
Cuntao Yu

AbstractOBJECTIVESThere are conflicting views regarding the status of valve-sparing root replacement (VSRR) as a proper treatment for acute type A aortic dissection (AAAD). Our goal was to compare the early and late outcomes of VSRR versus those of the Bentall procedure in patients with AAAD.METHODSWe performed a systematic review and meta-analysis of 9 studies to compare the outcomes of VSRR with those of the Bentall procedure in patients with AAAD. We focused on the following issues: early and late mortality rates, re-exploration, thromboembolization/bleeding events, infective endocarditis and reintervention rates.RESULTSA total of 706 patients with AAAD who underwent aortic root surgery were analysed; 254 patients were treated with VSRR and 452 with the Bentall procedure. VSRR was associated with a reduced risk of early death [odds ratio (OR) 0.34; 95% confidence interval (CI) 0.21–0.57] and late death (OR 0.34; 95% CI 0.21–0.57) compared with the Bentall procedure. No statistically significant difference was observed between the VSRR and Bentall groups with pooled ORs (OR 0.77; 95% CI 0.47–1.27, OR 0.61; 95% CI 0.32–1.18 and OR 0.71; 95% CI 0.23–2.15) for re-exploration, thromboembolization/bleeding and postoperative infective endocarditis, respectively. An increased risk of reintervention was observed for the VSRR compared to the Bentall group (OR 3.79; 95% CI 1.27–11.30). The pooled rate of reintervention incidence was 1.6% (95% CI 0.0–3.7%) and 0.4% (95% CI 0.0–1.3%) for the VSRR and the Bentall groups, respectively.CONCLUSIONSVSRR in patients with AAAD can be performed in experienced centres with excellent short- and long-term outcomes compared to those with the Bentall procedure and thus should be recommended especially for active young patients.


2016 ◽  
Vol 32 (10) ◽  
pp. S189
Author(s):  
H.N. Smith ◽  
M. Boodhwani ◽  
R. Saczkowski ◽  
M. Ouzounian ◽  
A.J. Gregory ◽  
...  

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
S Toh ◽  
D C M Yew ◽  
J J Choong ◽  
T L Chong ◽  
A Harky

Abstract Introduction Acute type A aortic dissection (ATAAD) is a life-threatening medical emergency requiring immediate surgical intervention. We sought to compare clinical outcomes in patients with ATAAD that undergone surgical repair during in-hours (IH) versus out-of-hours (OOH). Method Electronic database search at PubMed, Ovid, Scopus, Cochrane and Embase was performed from inception till March 2020. Primary outcomes were 30-day mortality, stroke, and re-operation for bleeding; secondary outcomes were previous cardiac surgery and total arch replacement. Results Six articles with a total of 3,744 patients met the inclusion criteria. Re-operation for bleeding and stroke rate were similar, with 18% in IH vs 23% in OOH (RR 0.89, 95% CI [0.73, 1.08], p = 0.24), and 12% in IH vs 13% in OOH (RR 0.83, 95% CI [0.66, 1.03], p = 0.09) respectively. 30-day mortality was significantly lower in IH (26%) vs 24% in OOH (RR 0.81, 95% CI [0.72, 0.90], p = 0.0001). Previous cardiac surgery was higher in IH (5%) vs 4% in OOH patients (p = 0.005). Total arch replacement were similar in both cohorts, 29% in IH vs 32% in OOH (RR 0.96, 95% CI [0.89, 1.04], p = 0.37). Conclusions ATAAD operation during IH and OOH have comparable clinical outcomes. Therefore, operating on such cases should be decided on clinical priority without delay.


2018 ◽  
Vol 55 (2) ◽  
pp. 201-209 ◽  
Author(s):  
Selim Mosbahi ◽  
Dushaj Stak ◽  
Isaac Gravestock ◽  
Jakob M Burgstaller ◽  
Johann Steurer ◽  
...  

Author(s):  
Simon De Freitas ◽  
Matthew J. Rossi ◽  
Steven D. Abramowitz ◽  
Javairiah Fatima ◽  
Misaki M. Kiguchi ◽  
...  

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