Comparison of the effect of 80 vs 40 mg atorvastatin in patients with isolated coronary artery bypass graft surgery: A randomized clinical trial

2019 ◽  
Vol 34 (8) ◽  
pp. 670-675
Author(s):  
Arash Shekari ◽  
Seyed K. Forouzannia ◽  
Tahereh Davarpasand ◽  
Azita H. Talasaz ◽  
Arash Jalali ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Randomized Clinical Trial ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Artery Bypass Graft

scholarly journals Modifying Stressors Using Betty Neuman System Modeling in Coronary Artery Bypass Graft: a Randomized Clinical Trial

2020 ◽  
Vol 9 (1) ◽  
pp. 13-19
Author(s):  
Elham Akhlaghi ◽  
Sima Babaei ◽  
Shahla Abolhassani
Keyword(s):  
Clinical Trial ◽  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Randomized Clinical Trial ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Control Group ◽  
Artery Bypass Graft ◽  
Personal Factors

Introduction: Coronary artery disease (CAD) is one of the major causes of mortality all over the world. In this relation, coronary artery bypass grafting (CABG) is one of the most important treatments for CAD patients. However, it leads to a lot of stress in the patient. The aim of this study was to use the Neuman model to moderate the stressors in patients undergoing coronary artery bypass graft. Methods: This study was a randomized clinical trial of two groups performed on patients admitted to the coronary artery bypass graft; and the study completed with 64 patients. The intervention was performed by the researcher according to the format of the Neuman Model, which included the investigation of the stressors, and the determination of the goals and strategies for the actions. Intrapersonal, interpersonal, and extra personal factors were evaluated using a Revised Cardiac Surgery Stressor Scale (RCSSS). The intervention program was designed by the researcher based on prevention levels using scientific resources. The collected data were analyzed in SPSS ver. 13 using descriptive and inferential statistics. Results: Before the intervention, the mean score of the stressors was not significantly different between the two groups. But immediately after the intervention and before discharging the intervention group, it was significantly less than the control group. Conclusion: Using a Neuman-based program as an effective and low-cost intervention can moderate the stressors and reduce the stress of patients awaiting coronary artery bypass graft. This theory can be a good guide to offering the roles needed to provide health services in the community.

scholarly journals The effect of N-acetyl cysteine injection on renal function after coronary artery bypass graft surgery :  A randomized clinical trial

2021 ◽  
Author(s):  
Fatemeh Javaherforoosh Zadeh ◽  
Zahra Shaker ◽  
Mahboobeh Rashidi ◽  
Reza Akhondzadeh ◽  
Fatemeh Hayati
Keyword(s):  
Clinical Trial ◽  
Renal Function ◽  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Randomized Clinical Trial ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Artery Bypass Graft ◽  
Acetyl Cysteine

Abstract Objective: This study aimed to compare the effects of N-acetyl cysteine on renal function after coronary artery bypass graft surgery.Method: In this randomized clinical trial conducted in Golestan Hospital, Ahvaz, Iran, 60 candidates for coronary artery bypass graft surgery were selected and divided into two N-acetyl cysteine and control groups (30 people each).Intervention: Patients received 3 (2 intraoperative and 1 postoperative) doses of IV N-acetyl cysteine (100 mg/kg) (n=30) or placebo (n=30) over 24 hour. Prescription times were as follows: after induction of anesthesia, in the Next 4 hours, and in the 16 hours after on. Primary outcomes were serum levels of BUN and Cr, at baseline,4 and 48 hours after surgery. And also need renal replacement therapy (RRT). Secondary outcomes included the hemodynamic variables, Blood products transfusionResults: There were significant differences in BUN between groups at 4 h (P= 0.02) and 48h after surgery (P=0.001) There were significant differences in Cr level between groups at 4 h (P <0.001) and 48h after surgery (P=0.001). MAP at different times (at 4h p=0.002 and 48h after surgery P<0.001) were significantly different between the two groups. There was a significant difference between the two groups in terms of the unit of Packed cell transfusion (P=0.002) and FFP transfusion (P<0.001).Conclusion: In the present study, we found that administration of N-acetyl cysteine can reduce the incidence of acute kidney injury in patients undergoing coronary artery bypass graft surgery and improved kidney functions.Trial registry: IRCT20190506043492N3 Registered at 2020.06.07

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