Efficacy and safety of two hyaluronic acid fillers with different injection depths for the correction of moderate‐to‐severe nasolabial folds: A 52‐week, prospective, randomized, double‐blinded study in a Chinese population

2022 ◽  
Author(s):  
Yifan Hu ◽  
Zhiyu Liu ◽  
Yao Wang ◽  
Qian Yu ◽  
Yu Gong ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Chinese Population ◽  
Efficacy And Safety ◽  
Blinded Study ◽  
Nasolabial Folds ◽  
Double Blinded

scholarly journals Fentanyl-sparing Effect of Acetaminophen as a Mixture of Fentanyl in Intravenous Parent-/Nurse-controlled Analgesia after Pediatric Ureteroneocystostomy

2010 ◽  
Vol 113 (3) ◽  
pp. 672-677 ◽  
Author(s):  
Jeong-Yeon Hong ◽  
Won Oak Kim ◽  
Bon Nyeo Koo ◽  
Jin Sun Cho ◽  
Eun H. Suk ◽  
...  
Keyword(s):  
Side Effects ◽  
Infusion Rate ◽  
Loading Dose ◽  
Efficacy And Safety ◽  
Pediatric Pain ◽  
Pain Scores ◽  
Blinded Study ◽  
Sparing Effect ◽  
Double Blinded ◽  
Fentanyl Group

Background Although acetaminophen has been used widely and is well tolerated in children, its efficacy and safety have not been clarified when combined with an opioid in intravenous parent-/nurse-controlled postoperative analgesia. Methods Sixty-three children (aged 6-24 months) who had undergone elective ureteroneocystostomies were enrolled in this prospective, randomized, double-blinded study. After the surgery, an analgesic pump was programmed to deliver fentanyl at a basal infusion rate of 0.25 microg.kg(-1).h(-1) and 0.25 microg/kg bolus after a loading dose of 0.5 microg/kg(-1). In the fentanyl-acetaminophen group, acetaminophen was coadministered as a solution mixture at a basal infusion rate of 1.5 mg.kg(-1).h(-1) and 1.5 mg/kg bolus after a loading dose of 15 mg/kg, whereas saline was administered to the fentanyl group. Results Postoperative pain scores were similar between the two groups. The total dose (micrograms per kilogram per day, mean+/-SD) of fentanyl at postoperative days 1 (8.3+/-3.7 vs. 18.1+/-4.6, P=0.021) and 2 (7.0+/-2.4 vs. 16.6, P=0.042) was significantly less in the fentanyl-acetaminophen group compared with that in the fentanyl group. The incidences of vomiting (16.1 vs. 56.3%, P=0.011) and sedation (9.7 vs. 46.9%, P=0.019) were significantly lower in the fentanyl-acetaminophen group than those in the fentanyl group. Conclusions Acetaminophen has significant fentanyl-sparing effects and reduces side effects when combined with fentanyl in intravenous parent-/nurse-controlled analgesia for postoperative pediatric pain management.

Efficacy and safety of a new monophasic hyaluronic acid filler in the correction of nasolabial folds: a randomized, evaluator-blinded, split-face study

2013 ◽  
Vol 25 (5) ◽  
pp. 448-452 ◽  
Author(s):  
Do Young Rhee ◽  
Chong Hyun Won ◽  
Sung Eun Chang ◽  
Tai Kyung Noh ◽  
Myoung Shin Kim ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Efficacy And Safety ◽  
Nasolabial Folds ◽  
Split Face

The efficacy and safety of a monophasic hyaluronic acid filler in the correction of nasolabial folds: A randomized, multicenter, single blinded, split-face study

2017 ◽  
Vol 17 (4) ◽  
pp. 584-589
Author(s):  
Hyun Jung Kwon ◽  
Eun Jung Ko ◽  
Sun Young Choi ◽  
Eun Ja Choi ◽  
Yu-Jin Jang ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Efficacy And Safety ◽  
Nasolabial Folds ◽  
Split Face
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