Evaluation of epicardial fat thickness and the ankle‐brachial index in patients with rosacea: A case‐control study

Author(s):  
Aslı Aksu Çerman ◽  
Arzu Er Kara ◽  
Ezgi Aktaş Karabay ◽  
Hazel Ezgi Kaya ◽  
İlknur Kıvanç Altunay
2021 ◽  
Vol 34 ◽  
pp. 151-153
Author(s):  
KARLA C. ARANA-PAZOS ◽  
JORGE L. NARVAEZRIVERA ◽  
ALBERTO MACEDA-SERRANO ◽  
DANIEL R. BENITEZ-MALDONADO ◽  
ALBERTO FRANCISCO RUBIO-GUERRA

Background An increase in epicardial fat thickness (EFT) has been associated with increased cardiovascular risk and the development of atherosclerosis. Transthoracic echo-cardiography provides a reliable measurement of EFT. We evaluated the relationship of EFT with carotid intima–media thickness (CIMT) and ankle–brachial index (ABI), in patients with metabolic syndrome. Methods We assessed 80 patients with metabolic syndrome who underwent echocardiography; EFT was measured by two cardiologists. The CIMT (B-mode colour imaging of extracranial carotid arteries using high-resolution ultrasound) was also measured by a certified ultrasonographer, and ABI was measured by the main researcher. Results We did not find any correlation between ABI with EFT (r=0.0103, p=0.93) or with CIMT (r=–0.1625, p=0.15). However, we found a significant correlation between EFT and CIMT (r=0.2718, r2=0.074, p=0.015). When we evaluated the risk for a CIMT >0.9 mm in patients with an EFT >3 mm, we found a statistically significant association (p=0.039). Interestingly, only 1 patient with an EFT <3 mm had a CIMT >0.9 mm. Conclusion We found that the EFT correlates with CIMT in patients with metabolic syndrome, which explains, at least in part, the higher risk of atherosclerosis in them. Measurement of EFT should be part of the cardiovascular risk evaluation in patients with metabolic syndrome.


2019 ◽  
Vol 09 (12) ◽  
pp. 958-968
Author(s):  
Baïdy Sy Kane ◽  
Maïmouna Sow ◽  
Fatou Aw ◽  
Abdourahmane Samba ◽  
Ahmed Tall Lemrabott ◽  
...  

2016 ◽  
Vol 36 (suppl_1) ◽  
Author(s):  
Nelson A Lopez

Cardiovascular risk factors in patients with perpheral arterial disease: a case -control study in Popayan-Colombia. Nelson Lopez, Lorena Urbano, Wilson Muñoz, Carlos H. Sierra-Torres. Introduction: Peripheral arterial disease is the third cause of atherosclerotic cardiovascular disease and the prevalence is higher in countries with lower -middle income. Objetives: To identify cardiovascular risk factors associated with peripheral arterial disease in Popayan-Colombia. Materials and methods: Included 500 cases and 500 controls in a observacional, analytical, case-control (1-1) study, informed consent, epidemiological survey, screening through the ankle-brachial index, anthropometric and biomedical tests were performed. The statical anlizes with SPSS version 22. Results: The pathology study, increased significantly with age, ocurring more frequently (43.2%). in subjects between 70-79 years of age and increasing for both genres in each decade of life, the disease was more common in womwn (53.4%) subjcts from urban (63.8%). The third part of men and women were asymptomatic. 8.6% of reported ischemic pain, while 6.7% of women were ulceration or gangrene. Conclusios: The main risk factors associated with peripheral arterial disease in Popayan -Colombia- were identified indicating that there is need to develop strategies for effective detection and prevention, using the ankle-brachial index in primary care health. ABI measurement should be used as a screening test in patients with médium to high risk in Colombia to improve strategies to reduce mortality from cardiovascular disease.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhenhong Zhang ◽  
Qian Xu ◽  
Yanping Chen ◽  
Lun Sui ◽  
Lu Jiang ◽  
...  

Abstract Background Gestational diabetes mellitus (GDM) has become alarming public health concern. It is associated with adverse pregnancy outcomes and increased risk of postpartum type 2 diabetes. Pre-pregnant body mass index (BMI), waist circumference and other anthropometric parameters have been proposed to predict GDM. However, visceral fat thickness can better reflect the distribution of body fat, and may more accurately predict the risk of GDM. Visceral fat thickness may lead to insulin resistance by regulating the adipose-derived exosomes miRNA-148 family, which affect the development of GDM. Evidence from prospective cohort studies on visceral fat thickness as a predictor of GDM and the possible mechanisms is still insufficient. Methods In this prospective cohort study, we will recruit 3000 women at first antenatal visit between 4 and 12 weeks of gestation. Baseline socio-demographic factors and visceral fat thickness will be assessed by questionnaire form and the ultrasonic measurement, respectively. At 20 weeks of gestation, 10 ml blood samples will be drawn and we will extract adipose-derived exosomes miRNA on the basis of nested case-control study. GDM will be screened at 24–28 weeks’ gestation and the expression of miRNA-148 family between pregnant women with GDM and without GDM will be analyzed. Intermediary analysis will be used to investigate whether visceral fat thickness can predict GDM by regulating adipose-derived exosomes miRNA-148 family. Discussion We hypothesized that visceral fat thickness may predict GDM by regulating the miRNA-148 family of adipose-derived exosomes. The findings of the study will assist in further clarifying the pathophysiological mechanism of GDM, it will also provide technical support for effective screening of high-risk pregnant women with GDM.


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