scholarly journals Comparison of 2.5% agarose gel vs hyaluronic acid filler, for the correction of moderate to severe nasolabial folds

2021 ◽  
Author(s):  
Nicolò Scuderi ◽  
Benedetta Fanelli ◽  
Pasquale Fino ◽  
Brian M. Kinney
Keyword(s):  
Hyaluronic Acid ◽  
Agarose Gel ◽  
Nasolabial Folds

Heparin and sulfated mucopolysaccharides—a micro system for quantitative differentiation and determination

1977 ◽  
Vol 55 (5) ◽  
pp. 1179-1189 ◽  
Author(s):  
Louis B. Jaques ◽  
Tak K. Sue ◽  
Norman M. McDuffie ◽  
Sandra M. Wice
Keyword(s):  
Aqueous Solution ◽  
Hyaluronic Acid ◽  
Optical Density ◽  
Toluidine Blue ◽  
Linear Relation ◽  
Cetylpyridinium Chloride ◽  
Agarose Gel ◽  
Azure A ◽  
Tissue Extracts ◽  
The Individual

Heparin (Hep), hyaluronic acid, chondroitins (sulfate) A, B, and C, and heparitins (sulfate) A, B, C, and D were subjected to microelectrophoresis in barbital–agarose gel, fixed with cetylpyridinium chloride and stained with toluidine blue. The optical densities of the resulting bands were compared with optical densities obtained upon reaction with azure A in aqueous solution and with the carbazole reagent. A linear relation was obtained between optical density and concentration of purified sulfated mucopolysaccharide (SMP). Less than 1 μg of Hep and 2 μg of other SMPs are required for measurement by electrophoresis, while about 30 μg of each is required with the carbazole reagent. The optical density of a mixture of SMPs was equal to the sum of the densities for the individual SMPs upon microelectrophoresis. It was demonstrated that the individual SMPs in mixtures were distinguished by reaction with specific enzymes and by changes in migration in agarose with barbital, phthalate, ethylenediamine, or propane-diamine buffers, permitting ready demonstration and quantitation of various SMP species. Examples are shown of the application of the procedure to measure the total SMPs and individual SMPs in tissue extracts. The method is sensitive, reproducible, flexible, and measures quantities [Formula: see text] of those measured colorimetrically, yet is relatively unaffected by protein, carbohydrate, or inorganic electrolytes.

Hyaluronic Acid Gel With (HARRL) and Without Lidocaine (HAJU) for the Treatment of Moderate-to-Severe Nasolabial Folds

2018 ◽  
Vol 44 (4) ◽  
pp. 549-556 ◽  
Author(s):  
Steven Fagien ◽  
Gary Monheit ◽  
Derek Jones ◽  
David Bank ◽  
Neil Sadick ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Acid Gel ◽  
Nasolabial Folds ◽  
Hyaluronic Acid Gel
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