Dermatologic adverse reactions to proton‐pump inhibitors: A synthetized review

2020 ◽  
Author(s):  
Antoine Salloum ◽  
Dayana Nasr ◽  
Diane Maalouf
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Adverse Reactions

Adverse reactions related to proton pump inhibitors in pediatric population: an analysis of spontaneous reporting data

2021 ◽  
Author(s):  
Valeria Dipasquale ◽  
Giuseppe Cicala ◽  
Francesca Laganà ◽  
Paola Cutroneo ◽  
Patrizia Felicetti ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Adverse Reactions ◽  
Spontaneous Reporting ◽  
Pediatric Population ◽  
Reporting Data

scholarly journals Proton Pump Inhibitor use in Hospitalized Patients: Is Overutilization Becoming a Problem?

2012 ◽  
Vol 5 ◽  
pp. CGast.S9588 ◽  
Author(s):  
Cheryl Durand ◽  
Kristine C. Willett ◽  
Alicia R. Desilets
Keyword(s):  
Clostridium Difficile ◽  
Proton Pump Inhibitor ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Clostridium Difficile Infection ◽  
Adverse Reactions ◽  
Recent Literature ◽  
Hospitalized Patients ◽  
Increased Risk ◽  
Appropriate Therapy

Proton pump inhibitors (PPIs) are among the most common classes of medications prescribed. Though they were previously thought of as safe, recent literature has shown risks associated with their use including increased risk for Clostridium difficile infection, pneumonia, and fractures. Due to these risks, it is important to determine if PPIs are being used appropriately. This review evaluates seven studies in hospitalized patients. Additionally, this review evaluates literature pertaining to recently discovered adverse reactions; all studies found PPIs are being overutilized. Findings highlight the importance of evaluating appropriate therapy with these agents and recommending discontinuation if a proper indication does not exist.

Proton Pump Inhibitors and the Risk of Community-Acquired Pneumonia: An Updated Meta-analysis

2021 ◽  
pp. 106002802110392
Author(s):  
Xuejiao Xun ◽  
Qifan Yin ◽  
Yuhao Fu ◽  
Xueru He ◽  
Zhanjun Dong
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Literature Search ◽  
Primary Outcome ◽  
Adverse Reactions ◽  
Meta Analysis ◽  
Community Acquired Pneumonia ◽  
Published Evidence ◽  
Increased Risk ◽  
Comprehensive Literature Search

Background: Some studies suggested an increased risk of community-acquired pneumonia (CAP) among proton pump inhibitors (PPI) users. However, the published evidence is inadequate to define the association between PPI use and the risk of CAP. Objective: The aims of our meta-analysis were to systematically assess the association between the risk of CAP and PPI use in adults to reduce the adverse effects of PPI and ensure the safety of medication for patients. Methods: A comprehensive literature search was conducted, published between January 1, 2004, and February 1, 2021. The primary outcome was the incidence of CAP. This meta-analysis was performed using odds ratios (ORs) with 95% CIs as effective measures; 13 studies including 2 098 804 patients were enrolled in our meta-analysis. Results: Our study revealed that the incidence of CAP was higher in PPI users than non -PPI users [OR = 1.37 (95% CI = 1.22–1.53)], especially for PPI duration < 30 days [OR = 1.49 (95% CI = 1.34–1.66)]. Compared with non-PPI use, PPI use increased the incidence of CAP in the stroke disease population [OR = 1.52 (95% CI = 1.33–1.75)], but not in the liver disease population [OR = 1.13 (95% CI = 0.98–1.30)]. Conclusions and Relevance: Using PPI could increase the risk of CAP when compared to not using PPI. PPI use increased the incidence of CAP in patients with stroke. Clinicians and clinical pharmacists should weigh the benefits before medication and strictly control the indication of the prescription, so as to reduce adverse reactions.

scholarly journals Adverse Reactions of Proton Pump Inhibitors: A Literature Review

2021 ◽  
Vol 13 (1) ◽  
pp. 25-27
Author(s):  
Dyêggo Carvalho Amorim ◽  
Matheus Pontes Parente Travassos ◽  
Igor Torres Dias ◽  
Hermano Queiroz Gurgel ◽  
Carlos Agusto Oliveira Meneses ◽  
...  
Keyword(s):  
Literature Review ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Adverse Reactions

Inhibitory effect of proton pump inhibitors against chemotaxis of Helicobacter pylori

2001 ◽  
Vol 120 (5) ◽  
pp. A655-A656
Author(s):  
H NAKAMURA ◽  
H YOSHIYAMA ◽  
H YANAI ◽  
M SHIRAL ◽  
T NAKAZAWA ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Inhibitory Effect

Abstract #728: Severe Hypomagnesemia and Breakthrough Seizure with Proton Pump Inhibitors Use

2015 ◽  
Vol 21 ◽  
pp. 139
Author(s):  
Muhammad Mahmood ◽  
Andrew Kinch ◽  
Woodall Brittany ◽  
Ayman Elkadry
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Breakthrough Seizure

Abstract #713 Proton Pump Inhibitors and Hypocalcemia: Does it Really Happen?

2018 ◽  
Vol 24 ◽  
pp. 157-158
Author(s):  
Franco Vallejo Garcia ◽  
Melissa Sum
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump

Erratum: Overutilization of Proton Pump Inhibitors: A Review of Cost-Effectiveness and Risk in PPI

2009 ◽  
Vol 104 (4) ◽  
pp. 1072-1072
Author(s):  
Joel J Heidelbaugh ◽  
Kathleen L Goldberg ◽  
John M Inadomi
Keyword(s):  
Cost Effectiveness ◽  
Proton Pump Inhibitors ◽  
Proton Pump
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