A randomized, split‐face, double‐blind, comparative study of the safety and efficacy of small‐ and large‐particle hyaluronic acid fillers for the treatment of nasolabial folds

Author(s):  
Andreas Nikolis ◽  
Kaitlyn M. Enright ◽  
Åke Öhrlund ◽  
Per Winlöf ◽  
Sebastian Cotofana
2012 ◽  
Vol 38 (7pt2) ◽  
pp. 1143-1150 ◽  
Author(s):  
Welf Prager ◽  
Esther Wissmueller ◽  
Isabel Havermann ◽  
Eva K. Bee ◽  
David J. Howell ◽  
...  

1981 ◽  
Vol 95 (3) ◽  
pp. 251-259 ◽  
Author(s):  
Maurice C. Gydé

AbstractThis was a double-blind randomized study to compare the safety and efficacy of timethoprim-polymyxin B (TP) and trimethoprim-sulfacetamide-polymyxin B (TSP) drops in the treatment of otorrhea. The 68 cases treated suffered from external otitis, recurrent otitis, recurrent otitis media with tympanic membrance perforation, or infected mastoid cavities and post-operative tympanoplasties. The TP ototopical solution was successful in 60·6 per cent of cases compared to 88·6 per cent of cases with TSP. These rates were statistically different using the Chi Square with Yates' correction method.There were no sings of ototoxicity, fungal infection overgrowth or local sensitivity to either of the solutions.The study has shown that both drugs are equally safe and that TSP is significantly more effective in the treatment of otorrhea.


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