scholarly journals A single‐center blinded randomized clinical trial to evaluate the anti‐aging effects of a novel HSF™‐based skin care formulation

2020 ◽  
Vol 19 (11) ◽  
pp. 2936-2945
Author(s):  
Dominik Duscher ◽  
Zeshaan N. Maan ◽  
Michael S. Hu ◽  
Dominik Thor
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Skin Care ◽  
Single Center ◽  
Aging Effects

Early Skin-to-skin Care with a Polyethylene Bag for Neonatal Hypothermia: A Randomized Clinical Trial

2020 ◽  
Author(s):  
Colm P. Travers ◽  
Manimaran Ramani ◽  
Samuel J. Gentle ◽  
Amelia Schuyler ◽  
Catherine Brown ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Skin Care ◽  
Skin To Skin ◽  
Neonatal Hypothermia

Melatonin reduces the mortality of severely-infected COVID-19 patients

2021 ◽  
Vol 4 (4) ◽  
pp. 613-616
Author(s):  
Dun-Xian Tan ◽  
Russel J Reiter
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Mortality Rate ◽  
Randomized Clinical Trial ◽  
Control Group ◽  
Mortality Reduction ◽  
Single Center ◽  
Open Label ◽  
Melatonin Treatment ◽  
The World

SARS-CoV-2 has ravaged the population of the world for two years. Scientists have not yet identified an effective therapy to reduce the mortality of severe COVID-19 patients. In a single-center, open-label, randomized clinical trial, it was observed that melatonin treatment lowered the mortality rate by 93% in severely-infected COVID-19 patients compared with the control group (see below). This is seemingly the first report to show such a huge mortality reduction in severe COVID-19 infected individuals with a simple treatment. If this observation is confirmed by more rigorous clinical trials, melatonin could become an important weapon to combat this pandemic.

scholarly journals Efficacy and efficiency of a new therapeutic approach based on activity-oriented proprioceptive antiedema therapy (TAPA) for edema reduction and improved occupational performance in the rehabilitation of breast cancer-related arm lymphedema in women: a controlled, randomized clinical trial

BMC Cancer ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
María Nieves Muñoz-Alcaraz ◽  
Luis Ángel Pérula-de-Torres ◽  
Jesús Serrano-Merino ◽  
Antonio José Jiménez-Vílchez ◽  
María Victoria Olmo-Carmona ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Group Intervention ◽  
Skin Care ◽  
Stage I ◽  
Current Evidence ◽  
Link Type ◽  
Proprioceptive Neuromuscular Facilitation ◽  
Arm Lymphedema

Abstract Background Breast cancer (BC) is a major public health issue. More than one out of five women treated for breast cancer will develop lymphedema in an upper extremity. Current evidence advocates transdisciplinary oncological rehabilitation. Therefore, research in this area is necessary since limited consensus having been reached with regard to the basic essential components of this rehabilitation. Consensus has, however, been reached on the use of decongestive lymphedema therapy (DLT), but due to a lack of tests, the necessary dosages are unknown and its level is moderately strong. This study attempts to verify both the efficacy of activity-oriented proprioceptive antiedema therapy (TAPA), as compared to conventional treatments such as DLT or Complex Physical Therapy (CPT), as well as its efficiency in terms of cost-effectiveness, for patients affected by breast cancer-related arm lymphedema. Methods Controlled, randomized clinical trial with dual stratification, two parallel arms, longitudinal and single blind. 64 women with breast cancer-related arm lymphedema will take part in the study. The experimental group intervention will be the same for stage I and II, and will consist of neuro-dynamic exercises oriented to the activity, proprioceptive neuromuscular facilitation activities and proprioceptive anti-edema bandaging. The control group intervention, depending on the stage, will consist of preventive measures, skin care and exercise-prescribed training in the lymphedema workshop as well as compression garments (Stage I) or conservative Complex Decongestive Therapy treatment (skin care, multi-layer bandaging, manual lymphatic drainage and massage therapy) (Stage II). Results Sociodemographic and clinical variables will be collected for the measurement of edema volume and ADL performance. Statistical analysis will be performed on intent to treat. Discussion It has been recommended that patient training be added to DLT, as well as a re-designing of patient lifestyles and the promotion of health-related aspects. In addition, clinical trials should be undertaken to assess neural mobilization techniques and proprioceptive neuromuscular facilitation should be included in the therapy. Cohesive bandaging will also be performed as an early form of pressotherapy. The proposed study combines all of these aspects in order to increased comfort and promote the participation of individuals with lymphedema in everyday situations. Limitations The authors have proposed the assessment of the experimental treatment for stages I and II. One possible limitation is the lack of awareness of whether or not this treatment would be effective for other stages as well as the concern for proper hand cleansing during use of bandages, given the current COVID-19 pandemic situation. Trial registration This trial was registered in ClinicalTrials.gov (NCT03762044). Date of registration: 23 November 2018. Prospectively Registered.

scholarly journals Effect of individualized diabetes education for type 2 diabetes mellitus: a single-center randomized clinical trial

2017 ◽  
Vol 16 (4) ◽  
pp. 1157
Author(s):  
Min-Hua Fan ◽  
Bing-Tong Huang ◽  
Ying-Chun Tang ◽  
Xiu-Hua Han ◽  
Wei-Wei Dong ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Clinical Trial ◽  
Type 2 Diabetes Mellitus ◽  
Randomized Clinical Trial ◽  
Diabetes Education ◽  
Single Center
Sign in / Sign up

Export Citation Format

Share Document