The role of oxidative stress in early-onset androgenetic alopecia

2016 ◽  
Vol 16 (4) ◽  
pp. 527-530 ◽  
Author(s):  
Hilal Kaya Erdogan ◽  
Isıl Bulur ◽  
Evin Kocaturk ◽  
Bahadir Yildiz ◽  
Zeynep Nurhan Saracoglu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Early Onset ◽  
Androgenetic Alopecia

Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Mahira Hamdy El Sayed ◽  
Marwa Yassin Soltan ◽  
Ahmed Sadek ◽  
Mohamed Abo Shabana Hussein Mohamed
Keyword(s):  
Side Effects ◽  
Hair Loss ◽  
Early Onset ◽  
University Hospital ◽  
Androgenetic Alopecia ◽  
Control Group ◽  
Terminal Hair ◽  
Reactive Oxygen Species Scavenger ◽  
Male Pattern

Abstract Background Androgenetic alopecia (AGA), the most common form of hair loss in men, involves the progressive loss of visible pigmented terminal hair on the scalp in response to circulating androgens. AGA is an autosomal disorder which begins in puberty in genetically predisposed individuals. Aim of the Work To study the effectiveness and safety of the reactive oxygen species scavenger Nacetyl-cysteine (NAC) as a single therapy and in combination with the topically applied minoxidil for treatment of the early-onset androgenetic alopecia in men. Patients and Methods The present study included 100 patients with male pattern hair loss whose age ranged from 18 to 30 years old, recruited from dermatology clinics in Ain Shams University Hospital and Kafr El Sheik University Hospital. Results Overall, all treatments could improve significantly some of the trichoscopic parameters as compared to the control group who did not receive any treatment. The number of terminal hair count increased and the vellus hair count decreased in response to either of treatments; minoxidil, NAC, or both as compared to control. These changes were noticed at both the vertex and frontotemporal sites. The treatment was generally tolerable and the side effects encountered did not necessitate stoppage of the treatment course. Conclusion On the basis of the findings of current study we can conclude that, the role of trichoscopy in increasing the accuracy for diagnosing hair disorders as well as to detect response or failure to treatment, N-acetylcysteine (NAC) improved significantly most of the trichoscopic features of AGA and it was was generally tolerable and the side effects encountered did not necessitate stoppage of the treatment course.

scholarly journals Evaluation of ischemia-modified albumin level and parameters related with oxidative stress in early onset androgenetic alopecia

TURKDERM ◽  
2017 ◽  
Vol 51 (4) ◽  
pp. 115-118
Author(s):  
Hülya Nazik ◽  
Selçuk Nazik ◽  
Zeynep Küskü Kiraz ◽  
Feride Çoban Gül ◽  
Betül Demir
Keyword(s):  
Oxidative Stress ◽  
Early Onset ◽  
Albumin Level ◽  
Androgenetic Alopecia ◽  
Ischemia Modified Albumin

792: Role of Oxidative Stress in Tumorigenic Potential of Bladder Cancer Cells

2005 ◽  
Vol 173 (4S) ◽  
pp. 214-215 ◽  
Author(s):  
Daniel Cho ◽  
Xiao Fang Ha ◽  
J. Andre Melendez ◽  
Louis J. Giorgi ◽  
Badar M. Mian
Keyword(s):  
Oxidative Stress ◽  
Bladder Cancer ◽  
Cancer Cells ◽  
Tumorigenic Potential ◽  
Bladder Cancer Cells

Gonadal profile in men with early-onset androgenetic alopecia: does a male PCOS-equivalent syndrome exist?

2017 ◽  
Author(s):  
Rossella Cannarella ◽  
Rosita A Condorelli ◽  
Sandro La Vignera ◽  
Laura M Mongioi ◽  
Enzo S Vicari ◽  
...  
Keyword(s):  
Early Onset ◽  
Androgenetic Alopecia
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