scholarly journals Morphological pattern of intrinsic nerve plexus distributed on the rabbit heart and interatrial septum

2014 ◽  
Vol 224 (5) ◽  
pp. 583-593 ◽  
Author(s):  
Inga Saburkina ◽  
Ligita Gukauskiene ◽  
Kristina Rysevaite ◽  
Kieran E. Brack ◽  
Audrys G. Pauza ◽  
...  
Keyword(s):  
Interatrial Septum ◽  
Rabbit Heart ◽  
Nerve Plexus ◽  
Morphological Pattern ◽  
Intrinsic Nerve

Atrioventricular nodal conduction during atrial fibrillation in rabbit heart

1982 ◽  
Vol 243 (5) ◽  
pp. H754-H760 ◽  
Author(s):  
T. Mazgalev ◽  
L. S. Dreifus ◽  
J. Bianchi ◽  
E. L. Michelson
Keyword(s):  
Atrial Fibrillation ◽  
Action Potentials ◽  
Atrioventricular Node ◽  
Interatrial Septum ◽  
Rabbit Heart ◽  
Relative Timing ◽  
Crista Terminalis ◽  
His Bundle ◽  
Atrioventricular Nodal Conduction ◽  
Variable Interaction

Atrial fibrillation was induced in 15 superfused rabbit atrial-atrioventricular nodal preparations in which surface bipolar electrograms were recorded simultaneously from the crista terminalis, interatrial septum, and His bundle along with microelectrode action potentials from cells in the atrionodal (AN), nodal (N), and nodal-His (NH) regions of the atrioventricular node. Effective engagement of the atrioventricular node with propagation to the His bundle was critically dependent on the relative timing of activation at the crista terminalis and interatrial septal input regions of the atrioventricular node. Conduction through the AN and N regions appeared dependent on the relative timing of activation wave fronts emerging from the two input regions. Asynchronous engagement of AN and N regions resulted in both distortion of action potentials and concealed conduction, with delayed conduction and block to the NH region and His bundle. Successful engagement of the NH region always produced a 1:1 NH-to-His bundle relationship. It is concluded that during atrial fibrillation 1) activation of the AN region occurs as a result of the variable interaction of inputs from the crista terminalis and interatrial septum; 2) predictably, effective synchronous engagement of the AN and consequently the N region is responsible for conduction to the NH and His bundle regions; 3) conversely, asynchronous activation inputs from the crista terminalis and interatrial septum result in fragmented, asynchronous as well as concealed conduction within the AN and N regions with block in the atrioventricular node and variable conduction to the His bundle.

Effects of atrial pacing site on rate-dependent AV nodal function in rabbit hearts

1995 ◽  
Vol 269 (3) ◽  
pp. H934-H942 ◽  
Author(s):  
F. Amellal ◽  
J. Billette
Keyword(s):  
Reference Site ◽  
Interatrial Septum ◽  
Rabbit Heart ◽  
Atrial Pacing ◽  
Similar Data ◽  
Stimulation Protocol ◽  
Crista Terminalis ◽  
Rate Dependent ◽  
A Minor ◽  
Nodal Properties

The functional origin of the changes in atrioventricular (AV) nodal function with the atrial pacing site was studied in isolated rabbit heart preparations. The rate-dependent AV nodal properties of recovery, facilitation, and fatigue were characterized with premature stimulation protocols repeated for each of three atrial pacing sites (upper atrium, low crista terminalis, and low interatrial septum). The effects of the atrial pacing site, reference site from which the beginning of nodal activation is measured (low crista and low septum) and stimulation protocol on nodal conduction and refractory parameters, were assessed with multifactorial analyses of variance. The changes in nodal parameters with the stimulation protocol did not differ significantly with the pacing site, indicating that the rate-dependent nodal properties are not affected by the atrial origin of the impulse. Only the baseline value of nodal parameters varied with the atrial pacing and reference site. However, the comparison of data obtained while the low crista was the pacing and reference site to those obtained while the low septum was the pacing and reference site yield no statistically significant differences, thus indicating that changes in perinodal activation were largely responsible for the observed changes in baseline. Upper atrial and low crista pacing yielded very similar data. We conclude that 1) the atrial pacing site affects perinodal activation but not rate-dependent nodal function, 2) the two inputs are equally effective in activating the AV node, and 3) input summation is a minor factor in rate-dependent nodal function.

scholarly journals Morphological pattern of mouse intrinsic cardiac nerve plexus

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Dainius H. Pauza ◽  
Kristina Rysevaite ◽  
Inga Saburkina ◽  
Marius Jokubauskas ◽  
Neringa Pauziene
Keyword(s):  
Nerve Plexus ◽  
Morphological Pattern ◽  
Cardiac Nerve
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