scholarly journals Neurotransmitter release in motor nerve terminals of a mouse model of mild spinal muscular atrophy

2013 ◽  
Vol 224 (1) ◽  
pp. 74-84 ◽  
Author(s):  
Rocío Ruiz ◽  
Lucía Tabares
Keyword(s):  
Mouse Model ◽  
Spinal Muscular Atrophy ◽  
Neurotransmitter Release ◽  
Muscular Atrophy ◽  
Motor Nerve ◽  
Nerve Terminals ◽  
Motor Nerve Terminals

The role of integrins in the modulation of neurotransmitter release from motor nerve terminals by stretch and hypertonicity

2003 ◽  
Vol 32 (5-8) ◽  
pp. 489-503 ◽  
Author(s):  
Alan D. Grinnell ◽  
Bo-Ming Chen ◽  
Amir Kashani ◽  
Jennifer Lin ◽  
Kazuhiro Suzuki ◽  
...  
Keyword(s):  
Neurotransmitter Release ◽  
Motor Nerve ◽  
Nerve Terminals ◽  
Motor Nerve Terminals

Total ganglioside ablation at mouse motor nerve terminals alters neurotransmitter release level

Synapse ◽  
2010 ◽  
Vol 64 (4) ◽  
pp. 335-338 ◽  
Author(s):  
Femke M.P. Zitman ◽  
Boyan Todorov ◽  
Keiko Furukawa ◽  
Koichi Furukawa ◽  
Hugh J. Willison ◽  
...  
Keyword(s):  
Neurotransmitter Release ◽  
Motor Nerve ◽  
Nerve Terminals ◽  
Total Ganglioside ◽  
Motor Nerve Terminals

Kv3 voltage-gated potassium channels regulate neurotransmitter release from mouse motor nerve terminals

2004 ◽  
Vol 20 (12) ◽  
pp. 3313-3321 ◽  
Author(s):  
Ruth E. Brooke ◽  
Thomas S. Moores ◽  
Neil P. Morris ◽  
Simon H. Parson ◽  
Jim Deuchars
Keyword(s):  
Potassium Channels ◽  
Neurotransmitter Release ◽  
Motor Nerve ◽  
Nerve Terminals ◽  
Motor Nerve Terminals ◽  
Voltage Gated

Effects of intravesicular loading of a Ca2+ chelator and depolymerization of actin fibers on neurotransmitter release in frog motor nerve terminals

2019 ◽  
Vol 50 (1) ◽  
pp. 1700-1711
Author(s):  
Kazuhiko Narita ◽  
Naoya Suzuki ◽  
Naoyuki Himi ◽  
Takashi Murayama ◽  
Toshitaka Nakagawa ◽  
...  
Keyword(s):  
Neurotransmitter Release ◽  
Motor Nerve ◽  
Nerve Terminals ◽  
Motor Nerve Terminals

scholarly journals Imaging of Calcium in Drosophila Larval Motor Nerve Terminals

1997 ◽  
Vol 78 (6) ◽  
pp. 3465-3467 ◽  
Author(s):  
Shanker Karunanithi ◽  
John Georgiou ◽  
Milton P. Charlton ◽  
Harold L. Atwood
Keyword(s):  
Neurotransmitter Release ◽  
Abdominal Segment ◽  
Imaging Techniques ◽  
Motor Nerve ◽  
Stimulus Frequency ◽  
Presynaptic Terminal ◽  
Nerve Terminals ◽  
Motor Nerve Terminals ◽  
Longitudinal Muscles ◽  
Single Synapse

Karunanithi, Shanker, John Georgiou, Milton P. Charlton, and Harold L. Atwood. Imaging of calcium in Drosophila larval motor nerve terminals. J. Neurophysiol. 78: 3465–3467, 1997. Calcium measurements in the presynaptic terminal are essential in the investigation of mechanisms underlying neurotransmitter release. To enhance the genetic analysis of secretory mechanisms, we have developed Ca2+ imaging techniques for Drosophila larval motor nerve terminals. We studied Ca2+ signals in “big” (type Ib) and “small” (type Is) boutons that innervate ventral longitudinal muscles 6 and 7 in each abdominal segment of Canton-S (CS)-strain 3rd instar larvae. The indicator fluo-3 in conjunction with confocal microscopy was used to detect stimulus-dependent changes in [Ca2+]i. The Ca2+ signals were reliable and reproducible, and the resting fluorescence remained constant throughout the experiments. The Ca2+ signals increased with stimulus frequency from 5 to 20 Hz for both bouton types. No significant differences in the Ca2+ signals were seen between the two bouton types at 5 and 20 Hz, but there was a difference at 10 Hz. The decay of the Ca2+ signal was more prolonged after 20-Hz stimulation than after 5 and 10 Hz. At the single-synapse level, the secretory efficacy of Is synapses is greater than that of Ib synapses, but our data show that factors other than differences in Ca2+ entry may govern the strength of synaptic transmission.

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