scholarly journals Reorganization of laryngeal motoneurons after crush injury in the recurrent laryngeal nerve of the rat

2013 ◽  
Vol 222 (4) ◽  
pp. 451-461 ◽  
Author(s):  
Ignacio Hernández-Morato ◽  
Francisco J. Valderrama-Canales ◽  
Gabriel Berdugo ◽  
Gonzalo Arias ◽  
Stephen McHanwell ◽  
...  
Keyword(s):  
Recurrent Laryngeal Nerve ◽  
Laryngeal Nerve ◽  
Crush Injury ◽  
Laryngeal Motoneurons

Nimodipine Improves Reinnervation and Neuromuscular Function after Injury to the Recurrent Laryngeal Nerve in the Rat

2007 ◽  
Vol 116 (8) ◽  
pp. 623-630 ◽  
Author(s):  
Jonas Hydman ◽  
Sten Remahl ◽  
Gunnar Björck ◽  
Mikael Svensson ◽  
Per Mattsson
Keyword(s):  
Recurrent Laryngeal Nerve ◽  
Motor Neurons ◽  
Neuromuscular Junctions ◽  
Neuromuscular Function ◽  
Nerve Fibers ◽  
Laryngeal Nerve ◽  
Crush Injury ◽  
Adult Rats ◽  
Somatotopic Organization ◽  
The Impact

Objectives: Injury of the recurrent laryngeal nerve (RLN) is associated with a high degree of neuronal survival, but leads to various levels of vocal fold motion impairment or laryngeal synkinesis, which has been attributed to misdirected reinnervation of the target muscles in the larynx or aberrant, competing reinnervation from adjacent nerve fibers. The aim of the present study was to evaluate the impact of the regeneration-promoting agent nimodipine on reinnervation and neuromuscular function following RLN crush injury. Methods: Sixty adult rats were randomized into nimodipine-treated or untreated groups and then underwent RLN crush injury. Reinnervation of the posterior cricoarytenoid muscle (PCA) was assessed by electrophysiological examination, retrograde tracing of lower motor neurons before and after injury, and quantification of neuromuscular junctions in the PCA muscle. Results: At 6 weeks after injury, the nimodipine-treated animals showed significantly enhanced neuromuscular function and also demonstrated a higher number of motor neurons in the brain stem that had reinnervated the PCA, compared to the untreated animals. The somatotopic organization of ambiguus motor neurons innervating the larynx was similar before injury and after reinnervation. Conclusions: Nimodipine improves regeneration and neuromuscular function following RLN injury in the adult rat, and could be of use in future strategies following RLN injury.

Erratum: Recurrent Laryngeal Nerve Dissection

1980 ◽  
Vol 45 (3) ◽  
Author(s):  
Frank B. Wilson ◽  
D. J. Oldring ◽  
Kathleen Mueller
Keyword(s):  
Case Report ◽  
Recurrent Laryngeal Nerve ◽  
Laryngeal Nerve ◽  
Long Period ◽  
Initial Surgery

On page 112 of the report by Wilson, Oldring, and Mueller ("Recurrent Laryngeal Nerve Dissection: A Case Report Involving Return of Spastic Dysphonia after Initial Surgery," pp. 112-118), the paraphrase from Cooper (1971), "if the patients are carefully selected and are willing to remain in therapy for a long period of time," was inadvertantly put in quotation marks.

The contribution of the recurrent laryngeal nerve in the motor innervation of the human cricopharyngeal muscle

1998 ◽  
Vol 23 (4) ◽  
pp. 377-377 ◽  
Author(s):  
Brok ◽  
Stroeve ◽  
Copper ◽  
B.W. Ongerboer De Visser ◽  
Schouwenburg
Keyword(s):  
Recurrent Laryngeal Nerve ◽  
Laryngeal Nerve ◽  
Motor Innervation ◽  
Cricopharyngeal Muscle

Short- and Long-Term Results of Total vs Subtotal Thyroid- ectomies in the Surgical Treatment of Graves' Disease

Swiss Surgery ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Robert ◽  
Mariéthoz ◽  
Pache ◽  
Bertin ◽  
Caulfield ◽  
...  
Keyword(s):  
Recurrent Laryngeal Nerve ◽  
Nerve Palsy ◽  
Recurrent Laryngeal Nerve Palsy ◽  
Laryngeal Nerve ◽  
Long Term Results ◽  
Graves Disease ◽  
Laryngeal Nerve Palsy ◽  
Short And Long Term

Objective: Approximately one out of five patients with Graves' disease (GD) undergoes a thyroidectomy after a mean period of 18 months of medical treatment. This retrospective and non-randomized study from a teaching hospital compares short- and long-term results of total (TT) and subtotal thyroidectomies (ST) for this disease. Methods: From 1987 to 1997, 94 patients were operated for GD. Thirty-three patients underwent a TT (mostly since 1993) and 61 a ST (keeping 4 to 8 grams of thyroid tissue - mean 6 g). All patients had received propylthiouracil and/or neo-mercazole and were in a euthyroid state at the time of surgery; they also took potassium iodide (lugol) for ten days before surgery. Results: There were no deaths. Transient hypocalcemia (< 3 months) occurred in 32 patients (15 TT and 17 ST) and persistent hypocalcemia in 8 having had TT. Two patients developed transient recurrent laryngeal nerve palsy after ST (< 3 months). After a median follow-up period of seven years (1-15) with five patients lost to follow-up, 41 patients having had a ST are in a hypothyroid state (73%), thirteen are euthyroid (23%), and two suffered recurrent hyperthyroidism, requiring completion of thyroidectomy. All 33 patients having had TT - with follow-ups averaging two years (0.5-8) - are receiving thyroxin substitution. Conclusions: There were no instances of persistent recurrent laryngeal nerve palsy in either group, but persistent hypoparathyroidism occurred more frequently after TT. Long after ST, hypothyroidism developed in nearly three of four cases, whereas euthyroidy was maintained in only one-fourth; recurrent hyperthyroidy was rare.

Technique of recurrent laryngeal nerve liberation for phonation recovery

2018 ◽  
Author(s):  
Radan Dzodic ◽  
Ivan Markovic ◽  
Nada Santrac ◽  
Marko Buta ◽  
Silvana Lukic
Keyword(s):  
Recurrent Laryngeal Nerve ◽  
Laryngeal Nerve

Causes of and Phonosurgical Treatment for Recurrent Laryngeal Nerve Paralysis.

2002 ◽  
Vol 53 (2) ◽  
pp. 107-112 ◽  
Author(s):  
Eiji Yumoto ◽  
Koji Nakano ◽  
Tetsuya Nakamoto ◽  
Takahiko Yamagata
Keyword(s):  
Recurrent Laryngeal Nerve ◽  
Laryngeal Nerve ◽  
Recurrent Laryngeal Nerve Paralysis ◽  
Nerve Paralysis ◽  
Laryngeal Nerve Paralysis
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