The Visual Spatial Learning Test: Differential impairment during the premanifest and manifest stages of Huntington's disease

2013 ◽  
Vol 9 (1) ◽  
pp. 77-86 ◽  
Author(s):  
Eva Pirogovsky ◽  
Diane R. Nicoll ◽  
Dillon M. Challener ◽  
Elizabeth Breen ◽  
Shea Gluhm ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Spatial Learning ◽  
Visual Spatial ◽  
Learning Test

Odor detection, learning, and memory in Huntington's disease

1999 ◽  
Vol 5 (7) ◽  
pp. 609-615 ◽  
Author(s):  
JOANNE M. HAMILTON ◽  
CLAIRE MURPHY ◽  
JANE S. PAULSEN
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Verbal Learning ◽  
Detection Sensitivity ◽  
Similar Amount ◽  
Odor Recognition ◽  
Odor Detection ◽  
Odor Learning ◽  
Olfactory Testing ◽  
Learning Test

We compared 7 mildly affected Huntington's disease (HD) patients to 7 age- and education-matched healthy controls (NC) on an odor detection test, the California Odor Learning Test, and the California Verbal Learning Test. Results demonstrated that odor detection sensitivity, but not group membership, accounted for significant variance in total olfactory learning. Both groups learned fewer items in the olfactory modality compared to the verbal modality, but retained a similar amount following a delay. No group differences were demonstrated for verbal recognition discriminability, but the HD group demonstrated significantly impaired odor recognition discriminability. Finally, odor detection provided excellent classification sensitivity and specificity between the patients and controls, suggesting that olfactory testing may provide a sensitive measure of the early disease process in HD. (JINS, 1999, 5, 609–615.)

scholarly journals Rate of forgetting for visual spatial information in patients with Huntington's disease

1999 ◽  
Vol 14 (8) ◽  
pp. 635-636
Author(s):  
J.D. Davis ◽  
J.V. Filoteo ◽  
L.M. Rilling ◽  
J.W. Roberts
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Spatial Information ◽  
Visual Spatial

scholarly journals New Yes/No Recognition Memory Analysis on the California Verbal Learning Test-3: Clinical Utility in Alzheimer’s and Huntington’s Disease

2018 ◽  
Vol 24 (8) ◽  
pp. 833-841
Author(s):  
Lisa V. Graves ◽  
Heather M. Holden ◽  
Emily J. Van Etten ◽  
Lisa Delano-Wood ◽  
Mark W. Bondi ◽  
...  
Keyword(s):  
Recognition Memory ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Clinical Utility ◽  
Verbal Learning ◽  
California Verbal Learning Test ◽  
Semantic Interference ◽  
Memory Disorder ◽  
Comparison Groups ◽  
Learning Test

AbstractObjectives: The third edition of the California Verbal Learning Test (CVLT-3) includes a new index termed List A versus Novel/Unrelated recognition discriminability (RD) on the Yes/No Recognition trial. Whereas the Total RD index incorporates false positive (FP) errors associated with all distractors (including List B and semantically related items), the new List A versus Novel/Unrelated RD index incorporates only FP errors associated with novel, semantically unrelated distractors. Thus, in minimizing levels of source and semantic interference, the List A versus Novel/Unrelated RD index may yield purer assessments of yes/no recognition memory independent of vulnerability to source memory difficulties or semantic confusion, both of which are often seen in individuals with primarily frontal-system dysfunction (e.g., early Huntington’s disease [HD]). Methods: We compared the performance of individuals with Alzheimer’s disease (AD) and HD in mild and moderate stages of dementia on CVLT-3 indices of Total RD and List A versus Novel/Unrelated RD. Results: Although AD and HD subgroups exhibited deficits on both RD indices relative to healthy comparison groups, those with HD generally outperformed those with AD, and group differences were more robust on List A versus Novel/Unrelated RD than on Total RD. Conclusions: Our findings highlight the clinical utility of the new CVLT-3 List A versus Novel/Unrelated RD index, which (a) maximally assesses yes/no recognition memory independent of source and semantic interference; and (b) provides a greater differentiation between individuals whose memory disorder is primarily at the encoding/storage level (e.g., as in AD) versus at the retrieval level (e.g., as in early HD). (JINS, 2018, 24, 833–841)

Visual Spatial Learning Test: Normative data and further validation.

1992 ◽  
Vol 4 (4) ◽  
pp. 433-441 ◽  
Author(s):  
James F. Malec ◽  
Robert J. Ivnik ◽  
Glenn E. Smith ◽  
Eric G. Tangalos ◽  
et al
Keyword(s):  
Spatial Learning ◽  
Normative Data ◽  
Visual Spatial ◽  
Learning Test

Visual Spatial Learning Test.

1991 ◽  
Vol 3 (1) ◽  
pp. 82-88 ◽  
Author(s):  
James F. Malec ◽  
Robert J. Ivnik ◽  
Nancy S. Hinkeldey
Keyword(s):  
Spatial Learning ◽  
Visual Spatial ◽  
Learning Test

scholarly journals Treadmill exercise enhances spatial learning ability through suppressing hippocampal apoptosis in Huntington’s disease rats

2015 ◽  
Vol 11 (3) ◽  
pp. 133-139 ◽  
Author(s):  
Eun-Sang Ji ◽  
You-Mi Kim ◽  
Mal-Soon Shin ◽  
Chang-Ju Kim ◽  
Kwang-Sik Lee ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Spatial Learning ◽  
Treadmill Exercise ◽  
Learning Ability ◽  
Hippocampal Apoptosis
Sign in / Sign up

Export Citation Format

Share Document