scholarly journals Distribution of androgen receptor mRNA in the prepubertal male and female mouse brain

2021 ◽  
Author(s):  
Alexandra L. Cara ◽  
Emily L. Henson ◽  
Bethany G. Beekly ◽  
Carol F. Elias
Keyword(s):  
Androgen Receptor ◽  
Mouse Brain ◽  
Female Mouse ◽  
Male And Female ◽  
Receptor Mrna

scholarly journals MicroRNA responses to focal cerebral ischemia in male and female mouse brain

2014 ◽  
Vol 7 ◽  
Author(s):  
Theresa A. Lusardi ◽  
Stephanie J. Murphy ◽  
Jay I. Phillips ◽  
Yingxin Chen ◽  
Catherine M. Davis ◽  
...  
Keyword(s):  
Cerebral Ischemia ◽  
Mouse Brain ◽  
Female Mouse ◽  
Focal Cerebral Ischemia ◽  
Male And Female

scholarly journals Characterization of Aromatase Expression in the Adult Male and Female Mouse Brain. I. Coexistence with Oestrogen Receptors α and β, and Androgen Receptors

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e90451 ◽  
Author(s):  
Davor Stanić ◽  
Sydney Dubois ◽  
Hui Kheng Chua ◽  
Bruce Tonge ◽  
Nicole Rinehart ◽  
...  
Keyword(s):  
Mouse Brain ◽  
Adult Male ◽  
Female Mouse ◽  
Androgen Receptors ◽  
Oestrogen Receptors ◽  
Aromatase Expression ◽  
Male And Female

Gene Expression Profile of the Neonatal Female Mouse Brain After Administration of Testosterone Propionate

2015 ◽  
Vol 12 (4) ◽  
pp. 887-896 ◽  
Author(s):  
Yutaka Nakachi ◽  
Mioko Iseki ◽  
Tomotaka Yokoo ◽  
Yosuke Mizuno ◽  
Yasushi Okazaki
Keyword(s):  
Gene Expression ◽  
Gene Expression Profile ◽  
Mouse Brain ◽  
Expression Profile ◽  
Female Mouse ◽  
Testosterone Propionate

Sex difference in the cytosolic and nuclear distribution of androgen receptor in mouse submandibular gland

1986 ◽  
Vol 108 (2) ◽  
pp. 267-273 ◽  
Author(s):  
S. Kyakumoto ◽  
R. Kurokawa ◽  
Y. Ohara-Nemoto ◽  
M. Ota
Keyword(s):  
Androgen Receptor ◽  
Nuclear Receptors ◽  
Binding Sites ◽  
Androgen Receptors ◽  
Dissociation Constants ◽  
Scatchard Analysis ◽  
Male And Female ◽  
Short Period ◽  
Almost All ◽  
Androgen Binding

ABSTRACT Cytosol and nuclear androgen receptors in submandibular glands of male and female mice were measured by an exchange assay at 0 °C. The binding of [3H]methyltrienolone to cytosol receptors in females was mostly saturated within a short period of incubation (3 h), whereas the saturation was much slower in males; suggesting that almost all of the cytosol receptors were unoccupied in females and the receptors were partially occupied in males. Nuclear receptors were extracted with pyridoxal 5′-phosphate (5 mmol/l) from nuclear fractions with 93–95% efficiency. The exchange of the bound steroids occurred by 24–48 h at 0 °C, suggesting that most of the nuclear androgen receptor was occupied. The binding was low at higher temperatures, probably due to inactivation of the receptor. Scatchard analysis showed that the apparent dissociation constants of cytosol and nuclear receptors were similar (0·8 and 0·9 nmol/l respectively) in both sexes. On the other hand, the number of androgen-binding sites in the nucleus was much higher in males than in females (1052 fmol/mg DNA and 32 fmol/mg DNA respectively), while the number in the cytosol was higher in females than in males (512 fmol/mg DNA and 368 fmol/mg DNA respectively). These observations show that androgen receptors exist mainly (74%) in the nuclei of males, while they exist mostly (94%) in the cytosol of females. J. Endocr. (1986) 108, 267–273

Age-related changes in ischemic tolerance in male and female mouse hearts

2005 ◽  
Vol 38 (2) ◽  
pp. 245-256 ◽  
Author(s):  
L WILLEMS ◽  
A ZATTA ◽  
K HOLMGREN ◽  
K ASHTON ◽  
J HEADRICK
Keyword(s):  
Female Mouse ◽  
Ischemic Tolerance ◽  
Male And Female ◽  
Age Related ◽  
Age Related Changes
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